Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: An RCT

Burns

Volumn 40, Issue 7, 2014, Pages 1300-1307

  Pretto, Giorgio ^a,b   Westphal, Glauco Adrieno ^c   Silva, Eliezer ^d,e  

^a São José Municipal Hospital at Joinville   (Brazil)

^b Serviço de Anestesiologia de Joinville   (Brazil)

^c Pharmacy School   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

Author keywords

Adrenergic alpha agonists; Analgesia; Anesthesia; Burns; Clonidine; Debridement; Hemodynamics; Ketamine; Psychological symptoms; Randomized controlled trial

Indexed keywords

CLONIDINE; ESKETAMINE; MIDAZOLAM; PLACEBO; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ANESTHETIC AGENT; ANXIOLYTIC AGENT; KETAMINE;

ABNORMAL DREAMING; ADULT; ANESTHESIA COMPLICATION; ANESTHESIA INDUCTION; ANESTHESIA MECHANISM; ANXIETY; ARTERIAL PRESSURE; ARTICLE; BURN; BURN DRESSING; BURN PATIENT; CLINICAL ARTICLE; CLINICAL EVALUATION; CONSCIENCE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEART RATE; HEMODYNAMICS; HUMAN; INTERVENTION STUDY; INTRAOPERATIVE AWARENESS; MALE; MENTAL DISEASE; NAUSEA AND VOMITING; POSTOPERATIVE ANALGESIA; POSTOPERATIVE DELIRIUM; PROSPECTIVE STUDY; PSYCHOLOGICAL ASPECT; PSYCHOPHARMACOTHERAPY; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; SURGICAL PATIENT; ANESTHESIA; BANDAGE; BURNS; DEBRIDEMENT; DISSOCIATIVE DISORDER; MIDDLE AGED; PROCEDURES; PSYCHOLOGY; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ADULT; ANESTHESIA; ANESTHETICS, DISSOCIATIVE; ANTI-ANXIETY AGENTS; BANDAGES; BURNS; CLONIDINE; DEBRIDEMENT; DISSOCIATIVE DISORDERS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; KETAMINE; MALE; MIDAZOLAM; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84908082421     PISSN: 03054179     EISSN: 18791409     Source Type: Journal    
DOI: 10.1016/j.burns.2014.07.022     Document Type: Article

References (20)

1. A.M. Al-Mousawi, G.A. Mecott-Rivera, M.G. Jeschke, and D.N. Herndon Burn teams and burn centers: the importance of a comprehensive team approach to burn care Clin Plast Surg 36 4 2009 547 554 [Epub 2009/10/02]
2. Z.P. Khan, C.N. Ferguson, and R.M. Jones Alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role Anaesthesia 54 2 1999 146 165 [Epub 1999/04/24]
3. N. MacLennan, D.M. Heimbach, and B.F. Cullen Anesthesia for major thermal injury Anesthesiology 89 3 1998 749 770 [Epub 1998/09/22]
4. T.A. Spanholtz, P. Theodorou, P. Amini, and G. Spilker Severe burn injuries: acute and long-term treatment Dtsch Arztebl Int 106 38 2009 607 613 [Epub 2009/11/06]
5. R.L. Sheridan Burns Crit Care Med 30 Suppl. 11 2002 S500 S514 [Epub 2003/01/17]
6. S.K. McGuinness, J. Wasiak, H. Cleland, J. Symons, L. Hogan, and T. Hucker A systematic review of ketamine as an analgesic agent in adult burn injuries Pain Med 12 10 2011 1551 1558 [Epub 2011/09/02]
7. G. Hocking, and M.J. Cousins Ketamine in chronic pain management: an evidence-based review Anesth Analg 97 6 2003 1730 1739 [Epub 2003/11/25]
8. M.T. Taittonen, O.A. Kirvela, R. Aantaa, and J.H. Kanto The effect of clonidine or midazolam premedication on perioperative responses during ketamine anesthesia Anesth Analg 87 1 1998 161 167 [Epub 1998/07/14]
9. N.S. Piccolo, C.M. Amaral, C.R. Leonardi, D.F. Novaes, F.N. Prestes, and M.A. Serra Sociedade Brasileira de Cirurgia Plástica 2002 Projeto Diretrizes Associação Médica Brasileira Conselho Federal de Medicina Disponível em http://www.projetodiretrizes.org.br/
10. G.C.R. Albornoz, C.J. Villegas, Y.I. Bravo, and M.V. Peña El GES promueve la equidad en el tratamiento del gran quemado de la tercera edad Revista médica de Chile 139 2011 1465 1470
11. T.L. Wachtel, C.C. Berry, E.E. Wachtel, and H.A. Frank The inter-rater reliability of estimating the size of burns from various burn area chart drawings Burns 26 2 2000 156 170 [Epub 2000/03/15]
12. J. Levanen, M.L. Makela, and H. Scheinin Dexmedetomidine premedication attenuates ketamine-induced cardiostimulatory effects and postanesthetic delirium Anesthesiology 82 5 1995 1117 1125 [Epub 1995/05/01]
13. F. Zor, S. Ozturk, F. Bilgin, S. Isik, and A. Cosar Pain relief during dressing changes of major adult burns: ideal analgesic combination with ketamine Burns 36 4 2010 501 505 [Epub 2009/10/13]
14. B. Maldini Ketamine anesthesia in children with acute burns and scalds Acta Anaesthesiol Scand 40 9 1996 1108 1111 [Epub 1996/10/01]
15. N. Elia, and M.R. Tramer Ketamine and postoperative pain - a quantitative systematic review of randomised trials Pain 113 1-2 2005 61 70 [Epub 2004/12/29]
16. R. Kohrs, and M.E. Durieux Ketamine: teaching an old drug new tricks Anesth Analg 87 5 1998 1186 1193 [Epub 1998/11/07]
17. T.A. Bowdle, A.D. Radant, D.S. Cowley, E.D. Kharasch, R.J. Strassman, and P.P. Roy-Byrne Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations Anesthesiology 88 1 1998 82 88 [Epub 1998/02/03]
18. S.C. Somashekara, D. Govindadas, G. Devashankaraiah, R. Mahato, S. Deepalaxmi, and V. Srinivas Midazolam premedication in attenuating ketamine psychological sequelae J Basic Clin Pharm 1 4 2010 209 213
19. R.F. Grace The effect of variable-dose diazepam on dreaming and emergence phenomena in 400 cases of ketamine-fentanyl anaesthesia Anaesthesia 58 9 2003 904 910 [Epub 2003/08/13]
20. H. Smith, and J. Elliott Alpha(2) receptors and agonists in pain management Curr Opin Anaesthesiol 14 5 2001 513 518 [Epub 2006/10/05]