Clinical factors associated with high-risk carotid plaque features as assessed by magnetic resonance imaging in patients with established vascular disease (from the AIM-HIGH Study)

American Journal of Cardiology

Volumn 114, Issue 9, 2014, Pages 1412-1419

  Zhao, Xue Qiao ^a   Hatsukami, Thomas S ^a   Hippe, Daniel S ^a   Sun, Jie ^a   Balu, Niranjan ^a   Isquith, Daniel A ^a   Crouse, John R ^b   Anderson, Todd ^c   Huston, John ^d   Polissar, Nayak ^b   O'Brien, Kevin ^a   Yuan, Chun ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c LIBIN CARDIOVASCULAR INSTITUTE OF ALBERTA   (Canada)

^d MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN A;

ADULT; AGED; ARTICLE; CAROTID ATHEROSCLEROSIS; CEREBROVASCULAR DISEASE; CORE LABORATORY; DIABETES MELLITUS; DISEASE ASSOCIATION; FEMALE; HIGH RISK PATIENT; HUMAN; IMAGE QUALITY; MAJOR CLINICAL STUDY; MALE; MEDICAL SOCIETY; METABOLIC SYNDROME X; NUCLEAR MAGNETIC RESONANCE IMAGING; VASCULAR DISEASE; VERY ELDERLY; CAROTID ARTERY; CAROTID ARTERY DISEASES; CLINICAL TRIAL; COMPARATIVE STUDY; FOLLOW UP; MIDDLE AGED; MULTICENTER STUDY; PATHOLOGY; PLAQUE, ATHEROSCLEROTIC; PROCEDURES; REPRODUCIBILITY; RETROSPECTIVE STUDY;

ADULT; AGED; AGED, 80 AND OVER; CAROTID ARTERIES; CAROTID ARTERY DISEASES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PLAQUE, ATHEROSCLEROTIC; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES;

EID: 84908077805     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2014.08.001     Document Type: Article

References (29)

1. M. Shinnar, J.T. Fallon, S. Wehrli, M. Levin, D. Dalmacy, Z.A. Fayad, J.J. Badimon, M. Harrington, E. Harrington, and V. Fuster The diagnostic accuracy of ex vivo MRI for human atherosclerotic plaque characterization Arterioscler Thromb Vasc Biol 19 1999 2756 2761
2. C. Yuan, L.M. Mitsumori, M.S. Ferguson, N.L. Polissar, D. Echelard, G. Ortiz, R. Small, J.W. Davies, W.S. Kerwin, and T.S. Hatsukami In vivo accuracy of multispectral magnetic resonance imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques Circulation 104 2001 2051 2056
3. L.M. Mitsumori, T.S. Hatsukami, M.S. Ferguson, W.S. Kerwin, J. Cai, and C. Yuan In vivo accuracy of multisequence MR imaging for identifying unstable fibrous caps in advanced human carotid plaques J Magn Reson Imaging 17 2003 410 420
4. V.C. Cappendijk, K.B. Cleutjens, A.G. Kessels, S. Heeneman, G.W. Schurink, R.J. Welten, W.H. Mess, M.J. Daemen, J.M. van Engelshoven, and M.E. Kooi Assessment of human atherosclerotic carotid plaque components with multisequence MR imaging: initial experience Radiology 234 2005 487 492
5. T. Saam, J.M. Cai, Y.Q. Cai, N.Y. An, A. Kampschulte, D. Xu, W.S. Kerwin, N. Takaya, N.L. Polissar, T.S. Hatsukami, and C. Yuan Carotid plaque composition differs between ethno-racial groups: an MRI pilot study comparing mainland Chinese and American Caucasian patients Arterioscler Thromb Vasc Biol 25 2005 611 616
6. S.E. Clarke, R.R. Hammond, J.R. Mitchell, and B.K. Rutt Quantitative assessment of carotid plaque composition using multicontrast MRI and registered histology Magn Reson Med 50 2003 1199 1208
7. J.M. Cai, T.S. Hatsukami, M.S. Ferguson, R. Small, N.L. Polissar, and C. Yuan Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging Circulation 106 2002 1368 1373
8. N. Takaya, J. Cai, M.S. Ferguson, V.L. Yarnykh, B. Chu, T. Saam, N.L. Polissar, J. Sherwood, R.C. Cury, R.J. Anders, K.O. Broschat, D. Hinton, K.L. Furie, T.S. Hatsukami, and C. Yuan Intra- and interreader reproducibility of magnetic resonance imaging for quantifying the lipid-rich necrotic core is improved with gadolinium contrast enhancement J Magn Reson Imaging 24 2006 203 210
9. J. Cai, T.S. Hatsukami, M.S. Ferguson, W.S. Kerwin, T. Saam, B. Chu, N. Takaya, N.L. Polissar, and C. Yuan In vivo quantitative measurement of intact fibrous cap and lipid rich necrotic core size in atherosclerotic carotid plaque: a comparison of high-resolution, contrast-enhanced magnetic resonance imaging and histology Circulation 112 2005 3437 3444
10. N. Takaya, C. Yuan, B. Chu, T. Saam, H. Underhill, J. Cai, N. Tran, N.L. Polissar, C. Isaac, M.S. Ferguson, G.A. Garden, S.C. Cramer, K.R. Maravilla, B. Hashimoto, and T.S. Hatsukami Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI - initial results Stroke 37 2006 818 823
11. N. Singh, A.R. Moody, D.J. Gladstone, G. Leung, R. Ravikumar, J. Zhan, and R. Maggisano Moderate carotid artery stenosis: MRI-imaging depicted intraplaque hemorrhage predicts risk of cerebrovascular ischemic events in asymptomatic men Radiology 252 2009 502 508
12. N. Altaf, L. Daniels, P.S. Morgan, D. Auer, S.T. MacSweeney, A.R. Moody, and J.R. Gladman Detection of intraplaque hemorrhage by magnetic resonance imaging in symptomatic patients with mild to moderate carotid stenosis predicts recurrent neurological events J Vasc Surg 47 2008 337 342
13. S.S. Virani, W. Sun, R. Dodge, V. Nambi, J. Coresh, T.H. Mosley, A. Sharrett, E. Boerwinkle, C.M. Ballantyne, and B.A. Wasserman Carotid Artery Plaque Burden and Characteristics and Subsequent Risk of Incident Cardiovascular Events: The Atherosclerosis Risk in Communities (ARIC) Carotid Magnetic Resonance Imaging Study. Reported at AHA 2013
14. The AIM-HIGH Investigators The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol Rationale and study design. The Atherothrombosis Intervention in Metabolic syndrome with low HDL/high triglycerides: Impact on Global Health outcomes (AIM-HIGH) Am Heart J 161 2011 471 477
15. The AIM-HIGH Investigators Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy N Engl J Med 365 2011 2255 2267
16. H. Underhill, V. Yarnykh, T. Hatsukami, J. Wang, N. Balu, C. Hayes, M. Oikawa, W. Yu, D. Xu, B. Chu, B.T. Wyman, N.L. Polissar, and C. Yuan Carotid plaque morphology and composition: initial comparison between 1.5- and 3.0-T magnetic field strengths Radiology 248 2008 550 560
17. W.S. Kerwin, C. Han, B. Chu, D. Xu, Y. Luo, J.N. Hwang, T.S. Hatsukami, and C. Yuan A quantitative vascular analysis system for evaluation of atherosclerotic lesions by MRI Medical Image Computing and Computer-Assisted Intervention-MICCAI 2001 2001 Springer Berlin, Germany 786 794
18. H.R. Underhill, T.S. Hatsukami, J. Cai, W. Yu, J.K. DeMarco, N.L. Polissar, H. Ota, X. Zhao, L. Dong, M. Oikawa, and C. Yuan A noninvasive imaging approach to assess plaque severity: the carotid atherosclerosis score AJNR Am J Neuroradiol 31 2010 1068 1075
19. D. Xu, D.S. Hippe, H.R. Underhill, M. Oikawa-Wakayama, L. Dong, K. Yamada, C. Yuan, and T.S. Hatsukami Prediction of high-risk plaque development and plaque progression with the carotid atherosclerosis score JACC Cardiovasc Img 7 2014 366 373
20. R Core Team Version 2.14.1. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria.
21. L. Dong, H.R. Underhill, W. Yu, H. Ota, T.S. Hatsukami, T.L. Gao, Z. Zhang, M. Oikawa, X. Zhao, and C. Yuan Geometric and compositional appearance of atheroma in an angiographically normal carotid artery in patients with atherosclerosis AJNR Am J Neuroradiol 31 2010 311 316
22. E. Arbustini, B. Dal Bello, P. Morbini, A.P. Burke, M. Bocciarelli, G. Specchia, and R. Virmani Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction Heart 82 1999 269 272
23. A. Farb, A.P. Burke, A.L. Tang, T.Y. Liang, P. Mannan, J. Smialek, and R. Virmani Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death Circulation 93 1996 1354 1363
24. H. Ota, M.J. Reeves, D.C. Zhu, A. Majid, A. Collar, C. Yuan, and J.K. DeMarco Sex differences in patients with asymptomatic carotid atherosclerotic plaque: in vivo 3.0-T magnetic resonance study Stroke 41 2010 1630 1635
25. J.J. Albers, A. Slee, K.D. O'Brien, J.G. Robinson, M.L. Kashyap, P.O. Kwiterovich Jr., P. Xu, and S.M. Marcovina Relationship of apolipoproteins A-1 and B, and lipoprotein(a) to cardiovascular outcomes: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes) J Am Coll Cardiol 62 2013 1575 1579
26. B.A. Wasserman, A.R. Sharrett, S. Lai, A.S. Gomes, M. Cushman, A.R. Folsom, D.E. Bild, R.A. Kronmal, S. Sinha, and D.A. Bluemke Risk factor associations with the presence of a lipid core in carotid plaque of asymptomatic individuals using high-resolution MRI: the Multi-Ethnic Study of Atherosclerosis (MESA) Stroke 39 2008 329 335
27. L. Wagenknecht, B.A. Wasserman, L. Chambless, J. Coresh, A. Folsom, T. Mosley, C. Ballantyne, R. Sharrett, and E. Boerwinkle Correlates of carotid plaque presence and composition as measured by MRI: the atherosclerosis risk in communities study Circ Cardiovasc Imaging 2 2009 314 322
28. M.Y. Desai, A. Rodriguez, B.A. Wasserman, G. Gerstenblith, S. Agarwal, M. Kennedy, D.A. Bluemke, and J.A. Lima Association of cholesterol subfractions and carotid lipid core measured by MRI Arterioscler Thromb Vasc Biol 25 2005 e110 e111
29. B.A. Phan, B. Chu, N. Polissar, T.S. Hatsukami, C. Yuan, and X.Q. Zhao Association of high-density lipoprotein levels and carotid atherosclerotic plaque characteristics by magnetic resonance imaging Int J Cardiovasc Imaging 23 2007 337 342