In vitro evaluation of three-dimensional single-walled carbon nanotube composites for bone tissue engineering

Journal of Biomedical Materials Research - Part A

Volumn 102, Issue 11, 2014, Pages 4118-4126

  Gupta, Ashim ^a   Main, Benjamin J ^a,b   Taylor, Brittany L ^c   Gupta, Manu ^d   Whitworth, Craig A ^a   Cady, Craig ^e   Freeman, Joseph W ^c   El Amin, Saadiq F ^a,f  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT SPRINGFIELD   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d MANIPAL COLLEGE OF DENTAL SCIENCES   (India)

^e BRADLEY UNIVERSITY   (United States)

^f Southern Illinois University at Carbondale   (United States)

Author keywords

Bone tissue engineering; PLAGA; SWCNT; SWCNT PLAGA composites; SWCNT PLAGA microspheres

Indexed keywords

BIOCOMPATIBILITY; BONE; CARBON; CELL ADHESION; CELL ENGINEERING; CELL PROLIFERATION; CELLS; COMPRESSIVE STRENGTH; GENE EXPRESSION; MECHANICAL TESTING; MICROSPHERES; TISSUE; TISSUE REGENERATION; YARN;

BONE TISSUE ENGINEERING; CELL PROLIFERATION RATE; GENE EXPRESSION ANALYSIS; ORTHOPEDIC APPLICATIONS; PLAGA; SINGLEWALLED CARBON NANOTUBE (SWCNT); SWCNT; ULTIMATE COMPRESSIVE STRENGTH;

SINGLE-WALLED CARBON NANOTUBES (SWCN);

ALKALINE PHOSPHATASE; BONE SIALOPROTEIN; COLLAGEN TYPE 1; OSTEOCALCIN; OSTEOPONTIN; POLYVINYL ALCOHOL; SINGLE WALLED NANOTUBE; TRANSCRIPTION FACTOR RUNX2; CARBON NANOTUBE; LACTIC ACID; MICROSPHERE; NANOCOMPOSITE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ARTICLE; BONE REGENERATION; BONE TISSUE; CELL ADHESION; CELL GROWTH; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CELL SURVIVAL; COMPRESSIVE STRENGTH; GENE EXPRESSION; IMMUNOFLUORESCENCE; OSTEOBLAST; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; YOUNG MODULUS; ANIMAL; BONE; CELL LINE; CHEMISTRY; MOUSE;

ANIMALS; BONE AND BONES; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; LACTIC ACID; MICE; MICROSPHERES; NANOCOMPOSITES; NANOTUBES, CARBON; POLYGLYCOLIC ACID; TISSUE ENGINEERING;

EID: 84908068292     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35088     Document Type: Article

References (27)

1. Giannoudis PV, Dinopoulos H, Tsiridis E. Bone substitutes: An update. Injury 2005;36:S20-S27.
2. Greenwald AS, Boden SD, Goldberg VM, Khan Y, Laurencin CT, Rosier RN. Bone-graft substitutes: Facts, fictions, and applications. J Bone Joint Surg Am 2001;83 (Suppl 2, Part 2):98-103.
3. Thein-Han WW, Misra RD. Biomimetic chitosan-nanohydroxyapatite composite scaffolds for bone tissue engineering. Acta Biomater 2009;5:1182-1197.
4. Laurencin CT, Ambrosio AM, Borden MD, Cooper JA Jr. Tissue engineering: Orthopedic applications. Annu Rev Biomed Eng 1999;1:19-46.
5. Mistry AS, Mikos AG. Tissue engineering strategies for bone regeneration. Adv Biochem Eng Biotechnol 2005;94:1-22.
6. Pellegrini G, Seol YJ, Gruber R, Giannobile WV. Pre-clinical models for oral and periodontal reconstructive therapies. J Dent Res 2009;88:1065-1076.
7. Petite H, Viateau V, Bensäd W, Meunier A, de Pollak C, Bourguignon M, Oudina K, Sedel L, Guillemin G. Tissue-engineered bone regeneration. Nat Biotechnol 2000;18:959-963.
8. Gupta A, Woods MD, Illingworth KD, Niemeier R, Schafer I, Cady C, Filip P, El-Amin SF III. Single walled carbon nanotube composites for bone tissue engineering. J Orthop Res 2013;31:1374-1381.
9. Athanasiou KA, Niederauer GG, Agrawal CM. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/ polyglycolic acid copolymers. Biomaterials 1996;17:93-102.
10. Lu L, Garcia CA, Mikos AG. In vitro degradation of thin poly (DL-lactic-co-glycolic acid) films. J Biomed Mater Res 1999;46: 236-244.
11. Laurencin CT, Nair LS. Nanotechnology and Tissue Engineering: The Scaffold: CRC Press, Boca Raton, FL; 2008.
12. Cui FZ, Li DJ. A review of investigations on biocompatibility of diamond-like carbon and carbon nitride films. Surf Coat Technol 2000;131:481-487.
13. Smart SK, Cassady AI, Lu GQ, Martin DJ. The biocompatibility of carbon nanotubes. Carbon 2006;44:1034-1047.
14. Sinha N, Yeow JT. Carbon nanotubes for biomedical applications. IEEE Trans Nanobiosci 2005;4:180-195.
15. Armentano I, Dottori M, Puglia D, Kenny JM. Effects of carbon nanotubes (CNTs) on the processing and in-vitro degradation of poly(DL-lactide-co-glycolide)/CNT films. J Mater Sci Mater Med 2008;19:2377-2387.
16. Saito N, Usui Y, Aoki K, Narita N, Shimizu M, Hara K, Ogiwara N, Nakamura K, Ishigaki N, Kato H, Taruta S, Endo M. Carbon nanotubes: Biomaterial applications. Chem Soc Rev 2008;38:1897-1903.
17. Hu H, Ni Y, Montana V, Haddon RC, Parpura V. Chemically functionalized carbon nanotubes as substrates for neuronal growth. Nano Lett 2004;4:507-511.
18. Zanello LP, Zhao B, Hu H, Haddon RC. Bone cell proliferation on carbon nanotubes. Nano Lett 2006;6:562-567.
19. Dias MR, Fernandes PR, Guedes JM, Hollister SJ. Permeability analysis of scaffolds for bone tissue engineering. J Biomech 2012;45:938-944.
20. Zhang Q, Mochalin VN, Neitzel I, Hazeli K, Niu J, Kontsos A, Zhou JG, Lelkes PI, Gogotsi Y. Mechanical properties and biomineralization of multifunctional nanodiamond-PLLA composites for bone tissue engineering. Biomaterials 2012;33:5067-5075.
21. Igwe JC, Mikael PE, Nukavarapu SP. Design, fabrication and in vitro evaluation of a novel polymer-hydrogel hybrid scaffold for bone tissue engineering. J Tissue Eng Regen Med 2012; DOI: 10.1002/term.1506.
22. Rho JY, Kuhn-Spearing L, Zioupos P. Mechanical properties and the hierarchical structure of bone. Med Eng Phys 1998;20:92-102.
23. Borden M, Attawia M, Khan Y, Laurencin CT. Tissue engineered microsphere-based matrices for bone repair: Design and evaluation. Biomaterials 2002;23:551-559.
24. Ajayan PM, Schadler LS, Giannaris C, Rubio A. Single-walled carbon nanotube-polymer composites: Strength and weakness. Adv Mater 2000;12:750-753.
25. Cheng Q, Rutledge K, Jabbarzadeh E. Carbon nanotube-poly(lactide- co-glycolide) composite scaffolds for bone tissue engineering applications. Ann Biomed Eng 2013;41:904-916.
26. Ambrose CG, Clyburn TA, Louden K, Joseph J, Wright J, Gulati P, Gogola GR, Mikos AG. Effective treatment of osteomyelitis with biodegradable microspheres in a rabbit model. Clin Orthop Relat Res 2004;421:293-299.
27. Fei Z, Hu Y, Wu D, Wu H, Lu R, Bai J, Song H. Preparation and property of a novel bone graft composite consisting of rhBMP-2 loaded PLGA microspheres and calcium phosphate cement. J Mater Sci Mater Med 2008;19:1109-1116.