Kruidenier et al. reply

Nature

Volumn 514, Issue 7520, 2014, Pages E2-

  Kruidenier, Laurens ^a   Chung, Chun Wa ^a   Cheng, Zhongjun ^b   Liddle, John ^a   Che, KaHing ^c   Joberty, Gerard ^a   Bantscheff, Marcus ^a   Bountra, Chas ^c   Bridges, Angela ^a   Diallo, Hawa ^a   Eberhard, Dirk ^a   Hutchinson, Sue ^a   Jones, Emma ^a   Katso, Roy ^a   Leveridge, Melanie ^a   Mander, Palwinder K ^a   Mosley, Julie ^a   Ramirez Molina, Cesar ^a   Rowland, Paul ^a   Schofield, Christopher J ^c   Sheppard, Robert J ^a   Smith, Julia E ^a   Swales, Catherine ^c   Tanner, Robert ^a   Thomas, Pamela ^a   Tumber, Anthony ^c   Drewes, Gerard ^a   Oppermann, Udo ^c   Patel, Dinshaw J ^b   Lee, Kevin ^a,d   Wilson, David M ^a   more..

^a GLAXOSMITHKLINE   (United Kingdom)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; GSK J1; GSK J2; GSK J3; GSK J4; HISTONE DEMETHYLASE; UNCLASSIFIED DRUG;

ASSAY; CHEMICAL ANALYSIS; DATA PROCESSING; INHIBITION;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG POTENCY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; IC50; IN VITRO STUDY; INFLAMMATION; ISOMER; MACROPHAGE; MASS SPECTROMETRY; PRIORITY JOURNAL; TISSUE CULTURE; U2OS CELL LINE; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IMMUNOLOGY; NOTE;

ANIMALS; ENZYME INHIBITORS; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; MACROPHAGES;

EID: 84908046721     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13689     Document Type: Article

References (2)

1. Heinemann, B. et al. Inhibition of demethylases by GSK-J1/J4. Nature 514, http://dx.doi.org/10.1038/nature13688 (2014).
2. Kruidenier, L. et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488, 404-408 (2012).