Multidrug-resistant organism infections in US nursing homes: A national study of prevalence, onset, and transmission across care settings, October 1, 2010–December 31, 2011

Infection Control and Hospital Epidemiology

Volumn 35, Issue , 2014, Pages S48-S55

  Kahvecioglu, Daver ^a   Ramiah, Kalpana ^b   McMaughan, Darcy ^c   Garfinkel, Steven ^b   McSorley, Veronica E ^b   Nguyen, Quy Nhi ^b   Yang, Manshu ^b   Pugliese, Christopher ^b   Mehr, David ^d   Phillips, Charles D ^c  

^a FANNIE MAE   (United States)

^b AMERICAN INSTITUTES FOR RESEARCH   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

^d University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE; AGED; ARTICLE; DISEASE TRANSMISSION; FEMALE; GENDER; GEOGRAPHIC DISTRIBUTION; HEALTH CARE COST; HOSPICE; HUMAN; INTELLECTUAL IMPAIRMENT; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MENTAL HOSPITAL; MULTIDRUG RESISTANCE; NURSING HOME; PREVALENCE; RURAL AREA; URBAN AREA; VERY ELDERLY; BACTERIAL INFECTIONS; CROSS INFECTION; MICROBIOLOGY; MIDDLE AGED; STATISTICS AND NUMERICAL DATA; TRANSMISSION; UNITED STATES; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL INFECTIONS; CROSS INFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NURSING HOMES; PREVALENCE; UNITED STATES; YOUNG ADULT;

EID: 84907997988     PISSN: 0899823X     EISSN: 15596834     Source Type: Journal    
DOI: 10.1086/677835     Document Type: Article

References (31)

1. Scott RD II. The direct medical costs of healthcare-associated infections in U.S. hospitals and the benefits of prevention. Atlanta: Centers for Disease Control and Prevention, 2009. http://www.cdc.gov/HAI/pdfs/hai/Scott_CostPaper.pdf. Accessed May 20, 2014.
2. Blumenstock J, Buchanan A, Cairns C, et al. Eliminating healthcare-associated infections: state policy options. Arlington, VA: Association of State and Territorial Health Officials, 2011. http://www.cdc.gov/hai/pdfs/toolkits/toolkit-hai-policy-final_01–2012.pdf.Accessed May 20, 2014.
3. Fenton T. Healthcare reformpressures hospitals to control HAIs. Lenexa, KS: Thermo Fisher Scientific, 2010. http://www.remel.com/hai/Article.aspx?IDp1. Accessed June 28, 2013.
4. Boucher HW, Talbot GH, Bradley JS, et al. Bad bugs, no drugs: no ESKAPE! an update from the Infectious Diseases Society of America. Clin Infect Dis 2009;48(1):1–12.
5. Gaynes R, Edwards JR. Overview of nosocomial infections caused by gram-negative bacilli. Clin Infect Dis 2005;41(6):848–854.
6. Denkinger CM, Grant AD, Denkinger M, Gautam S, D’Agata EM. Increased multi-drug resistance among the elderly on admission to the hospital—a 12-year surveillance study. Arch Gerontol Geriatr 2013;56(1):227–230.
7. Bonomo RA, Rice LB. Emerging issues in antibiotic resistant infections in long-term care facilities. J Gerontol A Biol Sci Med Sci 1999;54(6):B260–B267.
8. Raz R. The clinical impact of multiresistant gram-positive microorganisms in long-term care facilities. J Am Med Dir Assoc 2003;4(3 suppl):S100–S104.
9. Papia G, Louie M, Tralla A, Johnson C, Collins V, Simor AE. Screening high-risk patients for methicillin-resistant Staphylococcus aureus on admission to the hospital: is it cost effective. Infect Control Hosp Epidemiol 1999;20(7):473–477.
10. Huang SS1, Rifas-Shiman SL, Warren DK, et al. Improving methicillin-resistant Staphylococcus aureus surveillance and reporting in intensive care units. J Infect Dis 2007;195(3):330–338.
11. Lucet JC, Chevret S, Durand-Zaleski I, Chastang C, Regnier B; Multicenter Study Group. Prevalence and risk factors for carriage of methicillin-resistant Staphylococcus aureus at admission to the intensive care unit: results of a multicenter study. Arch Intern Med 2003;163(2):181–188.
12. Pop-Vicas AE, D’Agata EM. The rising influx of multidrugresistant gram-negative bacilli into a tertiary care hospital. Clin Infect Dis 2005;40(12):1792–1798.
13. Pop-Vicas A, Mitchell SL, Kandel R, Schreiber R, D’Agata EM. Multidrug-resistant gram-negative bacteria in a long-term care facility: prevalence and risk factors. J Am Geriatr Soc 2008;56(7): 1276–1280.
14. O’Fallon E, Pop-Vicas A, D’Agata E. The emerging threat of multidrug-resistant gram-negative organisms in long-term care facilities. J Gerontol A Biol Sci Med Sci 2009;64(1):138–141.
15. Loeb MB, Craven S, McGeer AJ, et al. Risk factors of resistance to antimicrobial agents among nursing home residents. Am J Epidemiol 2003;157(1):40–47.
16. Smith PW, Bennett G, Bradley S, et al. SHEA/APIC guideline: infection prevention and control in the long-term care facility. Am J Infect Control 2008;36(7):504–535.
17. Drinka PJ, Crnich CJ. An approach to endemic multi-drugresistant bacteria in nursing homes. J Am Med Dir Assoc 2005; 6(2):132–136.
18. Brennen C, Wagener MM, Muder RR. Vancomycin-resistant Enterococcus faecium in a long-term care facility. J Am Geriatr Soc 1998;46(2):157–160.
19. Strausbaugh LJ, Crossley KB, Nurse BA, Thrupp LD. Antimicrobial resistance in long-term-care facilities. Infect Control Hosp Epidemiol 1996;17(2):129–140.
20. Bradley SF. Issues in the management of resistant bacteria in long-term-care facilities. Infect Control Hosp Epidemiol 1999; 20(5):362–366.
21. Bradley SF. Methicillin-resistant Staphylococcus aureus: longterm care concerns. Am J Med 1999;106(5A):2S–10S; discussion 48S–52S.
22. Wiener J, Quinn JP, Bradford PA, et al. Multiple antibiotic–resistant Klebsiella and Escherichia coli in nursing homes. JAMA 1999;281(6):517–523.
23. McNeil SA, Mody L, Bradley SF. Methicillin-resistant Staphylococcus aureus: management of asymptomatic colonization and outbreaks of infection in long-term care. Geriatrics 2002; 57(6): 16-18, 21-24, 27.
24. Pacio GA, Visintainer P, Maguire G, Wormser GP, Raffalli J, Montecalvo MA. Natural history of colonization with vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus, and resistant gram-negative bacilli among long-termcare facility residents. Infect Control Hosp Epidemiol 2003;24(4): 246–250.
25. Rahimi AR. Prevalence and outcome of methicillin-resistant Staphylococcus aureus colonization in two nursing centers in Georgia. J Am Geriatr Soc 1998;46(12):1555–1557.
26. Trick WE, Weinstein RA, DeMarais PL, et al. Comparison of routine glove use and contact-isolation precautions to prevent transmission of multidrug-resistant bacteria in a long-term care facility. J Am Geriatr Soc 2004;52(12):2003–2009.
27. Ben-Ami R1, Schwaber MJ, Navon-Venezia S, et al. Influx of extended-spectrum beta-lactamase-producing enterobacteriaceae into the hospital. Clin Infect Dis 2006;42(7):925–934.
28. Elizaga ML, Weinstein RA, Hayden MK. Patients in long-term care facilities: a reservoir for vancomycin-resistant enterococci. Clin Infect Dis 2002;34(4):441–446.
29. Siegel JD, Rhinehart E, Jackson M, Chiarello L; Healthcare Infection Control Practices Advisory Committee. Management of multidrug-resistant organisms in health care settings, 2006. Am J Infect Control 2007;35(10 suppl 2):S165–S193.
30. Department of Health and Human Services Office of the Assistant Secretary for Planning and Evaluation; Centers for Medicare and Medicaid Services; Health Resource and Services Administration; Department of Labor’s Office of the Assistant Secretary for Policy, Bureau of Labor Statistics and Employment and Training. The future supply of long-term care workers in relation to the aging baby boom generation: report to Congress. 2003. http://aspe.hhs.gov/daltcp/reports/ltcwork.pdf. Accessed May 20, 2014.
31. Centers for Medicare and Medicaid Services. Nursing home quality initiative. MDS 3.0 for nursing homes and swing bed providers. Updated September 10, 2013. http://www.cms.gov/Medicare/Quality-Initiatives-Patient-Assessment-Instruments/NursingHomeQualityInits/NHQIMDS30.html. Accessed May 20, 2014.