Neonatal sepsis is mediated by maternal fever in labour epidural analgesia

Journal of Obstetrics and Gynaecology

Volumn 34, Issue 8, 2014, Pages 679-683

  Wassen, M M L H ^a   Winkens, B ^b   Dorssers, E M I ^a   Marcus, M A ^c   Moonen, R M J ^a   Roumen, F J M E ^a  

^a Zuyderland Medical Centre   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Epidural analgesia; Fever; Labour; Neonatal sepsis

Indexed keywords

C REACTIVE PROTEIN;

ADULT; ANALGESIA; ANTHROPOMETRIC PARAMETERS; ARTICLE; BLOOD CULTURE; CASE CONTROL STUDY; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE ASSOCIATION; EPIDURAL ANESTHESIA; FEMALE; FETUS OUTCOME; FEVER; HIGH RISK INFANT; HUMAN; INCIDENCE; LABOR; MAJOR CLINICAL STUDY; MATERNAL DISEASE; NEWBORN; NEWBORN SEPSIS; OUTCOME ASSESSMENT; PARITY; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; VAGINAL DELIVERY; ADVERSE EFFECTS; NETHERLANDS; PREGNANCY; PREGNANCY COMPLICATIONS; SEPSIS;

ANALGESIA, EPIDURAL; FEMALE; FEVER; HUMANS; INFANT, NEWBORN; NETHERLANDS; PREGNANCY; PREGNANCY COMPLICATIONS; RETROSPECTIVE STUDIES; SEPSIS;

EID: 84907979618     PISSN: 01443615     EISSN: 13646893     Source Type: Journal    
DOI: 10.3109/01443615.2014.925858     Document Type: Article

References (31)

1. Agakidis C, Agakidou E, Philip Th omas S, Murthy P, John Lloyd D. 2011. Labor epidural analgesia is independent risk factor for neonatal pyrexia. Journal of Maternal and Fetal Neonatal Medicine 24: 1128-1132.
2. Alexander JM. 2005. Epidural analgesia for labor pain and its relationship to fever. Clinical Perinatology 32: 777-787.
3. Andres Camacho-Gonzalez A, Spearman PW, Stoll BJ. 2013. Neonatal infectious diseases. Evaluation of neonatal sepsis. Pediatric Clinics of North America 60: 367-389.
4. Camann WR, Hortvet LA, Hughes N, Bader AM, Datta S. 1991. Maternal temperature regulation during extradural analgesia for labor. British Journal of Anaesthesia 67: 565-568.
5. Connell TG, Rele M, Cowley D, Buttery JP, Curtis N. 2007. How reliable is a negative blood culture result? Volume of blood submitted for culture in routine practice in a children ' s hospital. Pediatrics 119: 891-896.
6. De Jongh RF, Bosmans EP, Puylaert MJ, Ombelet WU, Vandeput HJ, Berghmans RA. 1997. Th e infl uence of anaesthetic techniques and type of delivery on peripartum serum interleukin-6 concentrations. Acta Anaesthesiologica Scandinavica 41: 853-860.
7. Fusi L, Steer PJ, Maresh MJ, Beard RW. 1989. Maternal pyrexia associated with the use of epidural analgesia in labor. Lancet 1: 1250-1252.
8. Goetz L, Cohen A, Frigoletto F Jr, Ringer SA, Lang JM, Lieberman E. 2001. Maternal epidural use and neonatal sepsis evaluation in afebrile mothers. Pediatrics 108: 1099-1102.
9. Goetz L, Evans T, Rivers J, Suresh MS, Lieberman E. 2002. Elevated maternal and fetal serum interleukin-6 levels are associated with epidural fever. American Journal of Obstetrics and Gynecology 187: 834-838.
10. Gonen R, Korobochka R, Degani S, Gaitini L. 2000. Association between epidural analgesia and intrapartum fever. American Journal of Perinatology 17: 127-130.
11. Greenwell EA, Wyshak G, Ringer SA, Johnson LC, Rivkin MJ, Lieberman E. 2012. Intrapartum temperature elevation, epidural use, and adverse outcome in term infants. Pediatrics 129: e447-e454.
12. Haque KN, Radford P. 2002. Epidural analgesia and fever. Pediatrics 110: 196-197.
13. Heesen M, Klö hr S, Rossaint R, Straube S, Van de Velde M. 2012. Labor epidural analgesia and anti-infectious management of the neonate: a meta-analysis. Journal of Perinatal Medicine 40: 625-630.
14. Herbst A, W ø lner-Hanssen P, Ingemarsson I. 1995. Risk factors for fever in labor. Obstetrics and Gynecology 86: 790-794.
15. Impey L, Greenwood C, MacQuillan K, Reynolds M, Sheil O. 2001. Fever in labor and neonatal encephalopathy: a prospective cohort study. British Journal of Obstetrics and Gynaecology 108: 594-597.
16. Kaul B, Vallejo M, Ramanathan S, Mandell G. 2001. Epidural labor analgesia and neonatal sepsis evaluation rate: a quality improvement study. Anesthesia and Analgesia 93: 986-990.
17. Lieberman E, Eichenwald E, Mathur G, Richardson D, Heffner L, Cohen A. 2000b. Intrapartum fever and unexplained seizures in term infants. Pediatrics 106: 983-988.
18. Lieberman E, Lang J, Richardson DK, Frigoletto FD, Heffer LJ, Cohen A. 2000a. Intrapartum maternal fever and neonatal outcome. Pediatrics 105: 8-13.
19. Lieberman E, Lang JM, Frigoletto F Jr., Richardson DK, Ringer SA, Cohen A. 1997. Epidural analgesia, intrapartum fever, and neonatal sepsis evaluation. Pediatrics 99: 415-419.
20. Neal PR, Kleiman MB, Reynolds JK, Allen SD, Lemons JA, Yu PL. 1986. Volume of blood submitted for culture from neonates. Journal of Clinical Microbiology 24: 353-356.
21. Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR. 1996. A simulation study of the number of events per variable in logistic regression analysis. Journal of Clinical Epidemiology 49: 1373-1379.
22. Petrova A, Demissie K, Rhoadss GG, Smulian JC, Marcella S, Ananth CV. 2001. Association of maternal fever during labor with neonatal and infant morbidity and mortality. Obstetrics and Gynecology 98: 20-27.
23. Philip J, Alexander JM, Sharma SK, Leveno KJ, McIntire DD, Wiley J. 1999. Epidural analgesia during labor and maternal fever. Anesthesiology 90: 1271-1275.
24. Polin RA, Committee on Fetus and Newborn. 2012. Management of neonates with suspected or proven early-onset bacterial sepsis. Pediatrics 129: 1006-1015.
25. Ramin SM, Gambling DR, Lucas MJ, Sharma SK, Sidawi JE, Leveno KJ. 1997. Randomized trial of epidural versus intravenous analgesia during labor. Anesthesiology 87: 487-494.
26. Riley LE, Celi AC, Onderdonk AB, Roberts DJ, Johnson LC, Tsen LC et al. 2011. Association of epidural-related fever and non-infectious infl ammation in term labor. Obstetrics and Gynecology 117: 588-595.
27. Segal S. Labor epidural analgesia and maternal fever. 2010. Anesthesia and Analgesia 111: 1467-1475.
28. Smulian JC, Bhandari V, Vintzileos AM, Shen-Schwarz S, Quashie C, Lai-Lin YL et al. 2003. Intrapartum fever at term: serum and histologic markers of infl ammation. American Journal of Obstetrics and Gynecology 188: 269-274.
29. Van der Ham DP, van der Heyden JL, Opmeer BC, Mulder AL, Moonen RM, van Beek JH et al. 2012. Management of late-preterm premature rupture of membranes: the PPROMEXIL-2 trial. American Journal of Obstetrics and Gynecology 207: 276.e1-10.
30. Viscomi CM, Manullang T. 2000. Maternal fever, neonatal sepsis evaluation, and epidural labor analgesia. Regional Anesthesia and Pain Medicine 25: 549-553.
31. Yancey MK, Zhang J, Schwars J, Dietrich CS 3rd, KlebanoffM. 2001. Labor epidural analgesia and intrapartum maternal hyperthermia. Obstetrics and Gynecology 98: 763-770.