Identification of an MLL4-GPS2 fusion as an oncogenic driver of undifferentiated spindle cell sarcoma in a child

Genes Chromosomes and Cancer

Volumn 53, Issue 12, 2014, Pages 991-998

  O'Meara, Elaine ^a   Stack, Deirdre ^a   Phelan, Susan ^a   Mcdonagh, Naomi ^a   Kelly, Lorna ^a   Sciot, Raf ^b   Debiec Rychter, Maria ^b   Morris, Thomas ^c   Cochrane, Doug ^d   Sorensen, Poul ^e   O'Sullivan, Maureen J ^a,c,f  

^a National Children's Research Centre   (Ireland)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^d BC CHILDREN S HOSPITAL   (Canada)

^e BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^f TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CHILD; CHILDHOOD CANCER; CHROMOSOME TRANSLOCATION 17; CHROMOSOME TRANSLOCATION 19; CONTROLLED STUDY; GENE EXPRESSION; GENE FUSION; GENE IDENTIFICATION; GENE REARRANGEMENT; GLIOBLASTOMA; HEPATITIS B VIRUS; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; MLL4 GPS2 GENE; PROSTATE CANCER CELL LINE; PROSTATE CARCINOMA; SPINDLE CELL SARCOMA; UNDIFFERENTIATED SPINDLE CELL SARCOMA; 3T3 CELL LINE; ANIMAL; BRAIN NEOPLASMS; CASE REPORT; CHROMOSOME 17; CHROMOSOME 19; COHORT ANALYSIS; FEMALE; GENE TRANSLOCATION; GENETICS; HEK293 CELL LINE; METABOLISM; MIDDLE AGED; MOUSE; PATHOLOGY; SARCOMA; VERY ELDERLY; YOUNG ADULT;

DNA BINDING PROTEIN; MLL4-GPS2 FUSION PROTEIN, HUMAN; ONCOPROTEIN; SIGNAL PEPTIDE;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BRAIN NEOPLASMS; CHILD; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 19; COHORT STUDIES; DNA-BINDING PROTEINS; FEMALE; GENE FUSION; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MIDDLE AGED; NIH 3T3 CELLS; ONCOGENE PROTEINS, FUSION; SARCOMA; TRANSLOCATION, GENETIC; YOUNG ADULT;

EID: 84907974571     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.22208     Document Type: Article

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