Reflux pattern and role of impedance-pH variables in predicting PPI response in patients with suspected GERD-related chronic cough

Alimentary Pharmacology and Therapeutics

Volumn 40, Issue 8, 2014, Pages 966-973

  Ribolsi, M ^a   Savarino, E ^b   De Bortoli, N ^c   Balestrieri, P ^a   Furnari, M ^d   Martinucci, I ^c   Casale, M ^a   Greco, F ^a   Salvinelli, F ^a   Savarino, V ^d   Marchi, S ^c   Cicala, M ^a  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ESOMEPRAZOLE; PROTON PUMP INHIBITOR;

ACID EXPOSURE TIME; ADULT; AGED; ARTICLE; CHRONIC COUGH; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE ACTIVITY; DISEASE ASSOCIATION; DRUG RESPONSE; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; IMPEDANCE; IMPEDANCE BASELINE; MAJOR CLINICAL STUDY; MALE; MULTICHANNEL INTRALUMINAL IMPEDANCE; PATHOLOGY; PATIENT MONITORING; PH MEASUREMENT; PREDICTIVE VALUE; PREDICTOR VARIABLE; PROBABILITY; PROSPECTIVE STUDY; SCORING SYSTEM; SYMPTOMATOLOGY; CHRONIC DISEASE; COMPLICATION; CONTROLLED CLINICAL TRIAL; COUGH; ESOPHAGEAL PH MONITORING; MIDDLE AGED; PH; YOUNG ADULT;

ADULT; AGED; CHRONIC DISEASE; COUGH; ELECTRIC IMPEDANCE; ESOPHAGEAL PH MONITORING; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; PROTON PUMP INHIBITORS; YOUNG ADULT;

EID: 84907904628     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/apt.12919     Document Type: Article

References (29)

1. Chang AB, Lasserson TJ, Kiljander TO, et al,. Systematic review and meta-analysis of randomized controlled trials of gastro-esophageal reflux interventions for chronic cough associated with gastro-oesophageal reflux. BMJ 2006; 332: 11-7.
2. French CL, Irwin RS, Curley FJ, et al,. Impact of chronic cough on quality of life. Arch Intern Med 1998; 158: 1657-61.
3. Irwin RS, Corrao WM, Pratter MR,. Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of specific therapy. Am Rev Respir Dis 1981; 123: 413-7.
4. Poe RH, Kallay MC,. Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment. Chest 2003; 123: 679-84.
5. Baldi F, Cappiello R, Cavoli C, et al,. Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole. World J Gastroenterol 2006; 12: 82-8.
6. Blondeau K, Dupont LJ, Mertens V, et al,. Improved diagnosis of gastro-oesophageal reflux in patients with unexplained chronic cough. Aliment Pharmacol Ther 2007; 15: 723-32.
7. Sifrim D, Dupont L, Blondeau K, et al,. Weakly acidic reflux in patients with chronic unexplained cough during 24 hour pressure, pH, and impedance monitoring. Gut 2005; 54: 49-54.
8. Decalmer S, Stovold R, Houghton LA, et al,. Chronic cough: relationship between microaspiration, gastroesophageal reflux, and cough frequency. Chest 2012; 142: 958-64.
9. Kessing BF, Bredenoord AJ, Weijenborg PW, et al,. Esophageal acid exposure decreases intraluminal baseline impedance levels. Am J Gastroenterol 2011; 106: 2093-7.
10. Ribolsi M, Emerenziani S, Borrelli O, et al,. Impedance baseline and reflux perception in responder and non-responder non-erosive reflux disease patients. Scand J Gastroenterol 2012; 47: 1266-73.
11. Borrelli O, Salvatore S, Mancini V, et al,. Relationship between baseline impedance levels and esophageal mucosal integrity in children with erosive and non-erosive reflux disease. Neurogastroenterol Motil 2012; 24: 828-e394.
12. Kahrilas PJ, Howden CW, Hughes N, et al,. Response of chronic cough to acid-suppressive therapy in patients with gastroesophageal reflux disease. Chest 2013; 143: 605-12.
13. Ours TM, Kavuru MS, Schilz RJ, et al,. A prospective evaluation of esophageal testing and a double-blind, randomized study of omeprazole in a diagnostic and therapeutic algorithm for chronic cough. Am J Gastroenterol 1999; 94: 3131-8.
14. Fisman EZ, Shapira I, Motro M, et al,. The combined cough frequency/severity scoring: a new approach to cough evaluation in clinical settings. J Med 2001; 32: 181-7.
15. Shaw MJ, Talley NJ, Beebe TJ, et al,. Initial validation of a diagnostic questionnaire for gastroesophageal reflux disease. Am J Gastroenterol 2001; 96: 52-7.
16. Savarino E, de Bortoli N, Zentilin P, et al,. Alginate controls heartburn in patients with erosive and nonerosive reflux disease. World J Gastroenterol 2012; 18: 4371-8.
17. Ribolsi M, Emerenziani S, Petitti T, et al,. Increased frequency and enhanced perception of reflux in non-erosive reflux disease patients non-responders to proton pump inhibitors. Dig Liver Dis 2012; 44: 549-54.
18. Dent J, Holloway RH, Toouli J, et al,. Mechanisms of lower oesophageal sphincter incompetence in patients with symptomatic gastro-oesophageal reflux. Gut 1988; 29: 1020-8.
19. Ing AJ, Ngu MC, Breslin AB,. Chronic persistent cough and gastro-oesophageal reflux. Thorax 1991; 46: 479-83.
20. Jafari J, Kuo P, Yazaki E, et al,. Comparing objective methods of cough detection for assessment of gastroesophageal reflux-associated cough. Gastroenterology 2012; 142 (Suppl. 1): S412-3.
21. De Bortoli N, Nacci A, Savarino E, et al,. How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related? World J Gastroenterol 2012; 18: 4363-70.
22. Farré R, Blondeau K, Clement D, et al,. Evaluation of oesophageal mucosa integrity by the intraluminal impedance technique. Gut 2011; 60: 885-92.
23. Savarino E, Zentilin P, Savarino V,. NERD: an umbrella term including heterogeneous subpopulations. Nat Rev Gastroenterol Hepatol 2013; 10: 371-80.
24. Martinucci I, de Bortoli N, Savarino E, et al,. Esophageal baseline impedance levels in patients with pathophysiological characteristics of functional heartburn. Neurogastroenterol Motil 2014; 26: 546-55.
25. Caviglia R, Ribolsi M, Gentile M, et al,. Dilated intercellular spaces and acid reflux at the distal and proximal oesophagus in patients with non-erosive gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2007; 25: 629-36.
26. Savarino E, Zentilin P, Mastracci L, et al,. Microscopic esophagitis distinguishes patients with non-erosive reflux disease from those with functional heartburn. J Gastroenterol 2013; 48: 473-82.
27. Kiljander TO, Salomaa ER, Hietanen EK, et al,. Chronic cough and gastro-oesophageal reflux: a double-blind placebo controlled study with omeprazole. Eur Respir J 2000; 16: 633-8.
28. Noordzij JP, Khidr A, Evans BA, et al,. Evaluation of omeprazole in the treatment of reflux laryngitis: a prospective, placebo-controlled, randomized, double-blind study. Laryngoscope 2001; 111: 2147-51.
29. Shaheen NJ, Crockett SD, Bright SD, et al,. Randomised clinical trial: high-dose acid suppression for chronic cough-a double-blind, placebo-controlled study. Aliment Pharmacol Ther 2011; 33: 225-34.