Individualizing the use of medications in children: Making goldilocks happy

Clinical Pharmacology and Therapeutics

Volumn 96, Issue 3, 2014, Pages 304-306

  Leeder, J S ^a   Brown, J T ^a   Soden, S E ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; ARIPIPRAZOLE; ATOMOXETINE; CENTRAL NERVOUS SYSTEM AGENTS; CITALOPRAM; CYTOCHROME P450 2C19; CYTOCHROME P450 3A4; ESCITALOPRAM; FLUOXETINE; HALOPERIDOL; IBUPROFEN; INDOMETACIN; LISDEXAMFETAMINE; METHYLPHENIDATE; OLANZAPINE; PIMOZIDE; QUETIAPINE; RISPERIDONE; SERTRALINE; SILDENAFIL; TRAZODONE;

ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; BIPOLAR DISORDER; CLINICAL PRACTICE; DRUG CLEARANCE; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; ERECTILE DYSFUNCTION; FOOD AND DRUG ADMINISTRATION; GENOTYPE; GILLES DE LA TOURETTE SYNDROME; GOLD STANDARD; HEALTH CARE COST; HEALTH INSURANCE; HEREDITY; HUMAN; INDIVIDUALIZATION; INTESTINE PERFORATION; IRRITABILITY; KNOWLEDGE; MENTAL DISEASE; MENTAL HEALTH SERVICE; OFF LABEL DRUG USE; PERSISTENT PULMONARY HYPERTENSION; PERSONALIZED MEDICINE; PHENOTYPE; PRACTICE GUIDELINE; PREMATURITY; PRESCRIPTION; PRIORITY JOURNAL; PUBLIC HEALTH;

AGE FACTORS; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DOSAGE CALCULATIONS; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; PATIENT SAFETY; PHARMACEUTICAL PREPARATIONS; PHARMACOGENETICS; PHARMACOKINETICS; PHENOTYPE; RISK ASSESSMENT; RISK FACTORS;

EID: 84907875737     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2014.130     Document Type: Article

References (5)

1. American Academy of Pediatrics Committee on Drugs. Off-label use of drugs in children. Pediatrics 133, 563-567 (2014).
2. Children's Health Spending Report (2009-2012). Health Care Cost Institute. (2014). Accessed 12 May 2014.
3. Moore, T.J., Furberg, C.D., Mattison, D.R. & Cohen, M.R. QuarterWatch Special Report on Children: Adverse Drug Events in Children Under Age 18. Institute for Safe Medication Practices. (2014). Accessed 12 May 2014.
4. Dunne, J. et al. Extrapolation of adult data and other data in pediatric drugdevelopment programs. Pediatrics 128, e1242-e1249 (2011).
5. Khalil, F. & Läer, S. Physiologically based pharmacokinetic modeling: Methodology, applications, and limitations with a focus on its role in pediatric drug development. J. Biomed. Biotechnol. 2011, 907461 (2011).