Investigation of the stabilizing effects of antioxidants and benzophenone-3 on desonide photostability

AAPS PharmSciTech

Volumn 15, Issue 5, 2014, Pages 1155-1162

  Rosa, Priscila ^a   Snovarski Salla, Ana Paula ^a   De Bona Da Silva, Cristiane ^a   Bueno Rolim, Clarice Madalena ^a   Horn Adams, Andréa Inês ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

antioxidants; benzophenone 3; desonide; photostability; stability

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; BUTYLATED HYDROXYANISOLE; BUTYLCRESOL; DESONIDE; OXYBENZONE; BENZOPHENONE DERIVATIVE; DERMATOLOGICAL AGENT; EXCIPIENT;

ARTICLE; CONTROLLED STUDY; DEGRADATION KINETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; PHOTOCHEMISTRY; PHOTODEGRADATION; PHOTOLYSIS; ROOM TEMPERATURE; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; VALIDATION STUDY; CHEMISTRY; MEDICINAL CHEMISTRY; RADIATION RESPONSE; TEMPERATURE; ULTRAVIOLET RADIATION; ULTRAVIOLET SPECTROPHOTOMETRY;

ANTIOXIDANTS; BENZOPHENONES; CHEMISTRY, PHARMACEUTICAL; DERMATOLOGIC AGENTS; DESONIDE; EXCIPIENTS; PHOTOCHEMISTRY; SPECTROPHOTOMETRY, ULTRAVIOLET; TEMPERATURE; ULTRAVIOLET RAYS;

EID: 84907866035     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-014-0149-0     Document Type: Article

References (26)

1. Grau PS. Corticoides tópicos: actualización. Med Cutan Iber Lat Am. 2006;34(1):33-8.
2. Ross TC, Geuer S, Ross S, Brost H. Recent advances in treatment strategies for atopic dermatitis. Drugs. 2004;64(23):2639-66.
3. Wyatt EL, Sutter SH, Drake LA. Farmacologia dermatológica. In: Goodman LS, editor. Goodman & Gilman: as bases farmacológicas da terapêutica. Seção XIV: dermatologia. 10th ed. Rio de Janeiro: McGraw-Hill; 2004. p. 1351-2.
4. Nichols WK. Hormônios e antagonistas hormonais. In: Gennaro AR, editor. A ciência e a prática da farmácia. 20th ed. Rio de Janeiro: Guanabara Koogan; 2004. p. 421.
5. Gelbard CM, Hebert AA. Desonide hydrogel: advances in vehicle technology. Expert Rev Dermatol. 2009;4(1):23-7.
6. DEF, 2012/13. Dicionário de especialidades farmacêuticas. 41st ed. Rio de Janeiro: EPUC; 2013.
7. Albini A, Fasani E. Drugs: photochemistry and photostability. Cambridge: The Royal Society of Chemistry; 1998. p. 11-4.
8. Iqbal J, Husain A, Gupta A. Photochemistry of desonide, a non fluorinated steroidal anti-inflammatory drug. Chem Pharm Bull. 2006;54(6):836-8.
9. Moore DE. Photophysical and photochemical aspects of drug stability. In: TØnessen HH, editor. Photostability of drugs and drug formulations. 2nd ed. Boca Raton: CRC Press LLC; 2004. p. 10-40.
10. Polefka TG, Meyer TA, Agin PP, Bianchini RJ. Effects of solar radiation on the skin. J Cosm Dermatol. 2011;11:134-43.
11. Dalla Santa F, Sperotto LE, Braga MP, Dalcin TCS, Codevilla CS, Meneghini LZ, et al. Development and validation of a simple stability-indicating LC-method and UVA phostability study of desonide hair lotion. Curr Anal Chem. 2013;9:659-67.
12. TØnessen HH. Photostability testing of drugs and drug formulations - why and how? In: TØnessen HH, editor. Photostability of drugs and drug formulations. 2nd ed. Boca Raton: CRC Press LLC; 2004. p. 1-7.
13. Yoshioka S, Stella VJ. Stability of drugs and dosage forms. New York: Kluwer Academic Publishers; 2002. p. 61-78. 135-7.
14. Rowe RC, Sheskey PJ, Owen SC. Handbook of pharmaceutical excipients. 5th ed. London: Pharmaceutical Press; 2006. p. 8. 32, 48, 79, 81, 371, 466, 629.
15. Watson DG. Pharmaceutical analysis. A textbook for pharmacy students and pharmaceutical chemists. Edinburgh: Elsevier Churchill Livingstone; 2005. p. 250-3.
16. ICH. International conference on harmonisation of technical requirements for registration of pharmaceuticals for human use. ICH harmonised tripartite guideline: guideline on validation of analytical procedure Q2R1 methodology; 2005. p. 9-10.
17. Khattak RS, Shaikh D, Ahmad I, Usmanghani K, Sheraz MA, Ahmed S. Photodegradation and stabilization of bethametasone-17 valerate in aqueous/organic solvents and topical formulations. AAPS PharmSciTech. 2012;14(1):177-82.
18. CDER. Center for drug evaluation and research. Reviewer guidance: Validation of chromatographic methods; 1994 p. 8-26.
19. Thoma K, Klimeck R. Photostabilization of drugs in dosage forms without protection from packaging materials. Int J Pharm. 1991;67:169-75.
20. Brisaert M, Vercarmmen PJ. Investigation on the photostability of a tretinoin lotion and stabilization with additives. Int J Pharm. 2000;199:49-57.
21. Gaspar LR, Maia Campos PMBG. Photostability and efficacy studies of topical formulations containing UV filters combination and vitamin A, C and E. Int J Pharm. 2007;343:189-91.
22. The MERCK. Index. 14th ed. Rahway: Merck & Co; 2006. p. 182.
23. Braga MP, Dalcin TCS, Rosa P, Codevilla CS, Silva CB, Rolim CMB, et al. Assay and photodegradation kinetics of desonide lotion by an LC-UV stability-indicating method. J Liq Chromatogr R T. 2014;37:1968-84.
24. Ricci A, Fasani E, Mella M, Albini A. General patterns in the photochemistry of pregna-1,4-dien-3,20-diones. J Org Chem. 2003;68:4361-6.
25. Carstensen JT, Rhodes CT. Drug stability. Principles and practices. New York: Informa Healthcare; 2007. p. 3-17.
26. Lachman L, Deluca P, Akers AJ. Testes de estabilidade e fundamentos de cinética química. In: Lachman L, Lieberman HA, Kanig JL, editors. Teoria e prática na indústria farmacêutica, v.2. Lisboa: Fundação Lacouste Gulbenkian; 2001. p. 1277-355.