Reproductive toxicology and clastogenic evaluation in mice of a phytotherapeutic formulation obtained from Cinchona calisaya Weddel (Rubiaceae) used in Brazilian folk medicine as female fertility stimulant

Journal of Ethnopharmacology

Volumn 155, Issue 3, 2014, Pages 1508-1512

  Do Amaral, Vera Lucia Langaro ^a   Frajbat, Marcel ^a   Petreanu, Marcel ^a   Zermiani, Tailyn ^a   De Freitas, Rilton Alves ^b   Maistro, Edson Luis ^c   Niero, Rivaldo ^a   Bresolin, Tania Mari Bellé ^a   Filho, Valdir Cechinel ^a   De Andrade, Sérgio Faloni ^a  

^a UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Inglesa ; Micronucleus; Reproductive toxicology; gua

Indexed keywords

AGUA INGLESA; CINCHONA EXTRACT; CLASTOGEN; MESYLIC ACID ETHYL ESTER; QUININE DERIVATIVE; UNCLASSIFIED DRUG; FERTILITY PROMOTING AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MARROW SUPPRESSION; CELL PROLIFERATION; CINCHONA; CINCHONA CALISAYA WEDDEL; CONTROLLED STUDY; CORPUS LUTEUM; DRUG MEGADOSE; EMBRYO; ESTRUS CYCLE; FEMALE; FEMALE FERTILITY; FETUS; FETUS WEIGHT; GENOTOXICITY; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MOUSE; NIDATION; NONHUMAN; PCE/NCE (ERYTHROCYTE); REPRODUCTIVE TOXICITY; RUBIACEAE; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; BRAZIL; DRUG EFFECTS; FETUS DEVELOPMENT; PHYTOTHERAPY; PREGNANCY; REPRODUCTION; TRADITIONAL MEDICINE;

ANIMALS; BONE MARROW CELLS; BRAZIL; CINCHONA; FEMALE; FERTILITY AGENTS; FETAL DEVELOPMENT; MALE; MEDICINE, TRADITIONAL; MICE, INBRED BALB C; MICRONUCLEUS TESTS; PHYTOTHERAPY; PREGNANCY; REPRODUCTION;

EID: 84907848673     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.07.038     Document Type: Article

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