Karyotype stability of human umbilical cord‑derived mesenchymal stem cells during in vitro culture

Experimental and Therapeutic Medicine

Volumn 8, Issue 5, 2014, Pages 1508-1512

  Ruan, Zhong Bao ^a   Zhu, Li ^a   Yin, Yi Gang ^a   Chen, Ge Cai ^a  

^a TAIZHOU PEOPLE S HOSPITAL   (China)

Author keywords

Human umbilical cord derived mesenchymal stem cells; Karyotyping; Serial passage

Indexed keywords

BETA1 INTEGRIN; CD31 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; CELL SURFACE MARKER; ENDOGLIN; HERMES ANTIGEN; HLA DR ANTIGEN; MICROSOMAL AMINOPEPTIDASE; THY 1 ANTIGEN;

ARTICLE; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMAN UMBILICAL CORD DERIVED MESENCHYMAL STEM CELL; IMMUNOPHENOTYPING; INFANT; KARYOTYPING; MALE; MESENCHYMAL STEM CELL; NORMAL HUMAN; STEM CELL CULTURE; UMBILICAL CORD;

EID: 84907845360     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.1977     Document Type: Article

References (16)

1. Tong CK, Vellasamy S, Tan BC, Abdullah M, Vidyadaran S, Seow HF and Ramasamy R: Generation of mesenchymal stem cell from human umbilical cord tissue using a combination and mechanical disassociation method. Cell Biol Int 35: 221-226, 2011.
2. Arufe MC, De la Fuente A, Fuentes I, Toro FJ and Blanco FJ: Umbilical cord as a mesenchymal stem cell source for treating joint pathologies. World J Orthop 2: 43-50, 2011.
3. Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN and Frenette PS: Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466: 829-834, 2010.
4. Montanucci P, Basta G, Pescara T, Pennoni I, Di Giovanni F and Calafiore R: New simple and rapid method for purification of mesenchymal stem cells from the human umbilical cord Wharton jelly. Tissue Eng Part A 17: 2651-2661, 2011.
5. Stewart MC and Stewart AA: Mesenchymal stem cells: characteristics, sources, and mechanisms of action.Vet Clin N Am Equine Pract 27: 243-261, 2011.
6. Ringden O and Le Blanc K: Mesenchymal stem cells for treatment of acute and chronic graft-versus-host disease, tissue toxicity and hemorrhages. Best Pract Res Clin Haematol 24: 65-72, 2011.
7. Kern S, Eichler H, Stoeve J, Klüter H and Bieback K: Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24: 1294-1301, 2006.
8. Cho H, Seo YK, Jeon S, Yoon HH, Choi YK and Park JK: Neural differentiation of umbilical cord mesenchymal stem cells by sub-sonic vibration. Life Sci 90: 591-599, 2012.
9. Matsuzuka T, Rachakatla RS, Doi C, Maurya DK, Ohta N, Kawabata A, Pyle MM, Pickel L, Reischman J, Marini F, Troyer D and Tamura M: Human umbilical cord matrix-derived stem cells expressing interferon-beta gene significantly attenuate bronchioloalveolar carcinoma xenografts in SCID mice. Lung Cancer 70: 28-36, 2010.
10. Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PC, Szuhai K, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, Prockop DJ, Fibbe WE and Blazar BR:Sarcoma derived from cultured mesenchymal stem cells. Stem Cells 25: 371-379, 2007.
11. Bagley RG, Weber W, Rouleau C, Yao M, Honma N, Kataoka S, Ishida I, Roberts BL and Teicher BA: Human mesenchymal stem cells from bone marrow express tumor endothelial and stromal markers. Int J Oncol 34: 619-627, 2009.
12. Fotino C, Ricordi C, Lauriola V, Alejandro R and Pileggi A: Bone marrow-derived stem cell transplantation for the treatment of insulin dependent diabetes. Rev Diabet Stud 7: 144-157, 2010.
13. Tolar J, Nauta AJ, Osborn MJ, Panoskaltsis Mortari A, McElmurry RT, Bell S, Xia L, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PC, Szuhai K, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, Prockop DJ, Fibbe WE and Blazar BR: Sarcoma derived from cultured mesenchymal stem cells.Stem Cells 25: 371-379, 2007.
14. Tasso R, Augello A, Carida' M, Postiglione F, Tibiletti MG, Bernasconi B, Astigiano S, Fais F, Truini M, Cancedda R and Pennesi G: Development of sarcomas in mice implanted with mesenchymal stemcells seeded onto bioscaffolds. Carcinogenesis 30: 150-157, 2009.
15. Li Q, Hisha H, Takaki T, Adachi Y, Li M, Song CH, Feng W, Okazaki S, Mizokami T, Kato J, Inaba M, Hosaka N, Maki M and Ikehara S: Trabsformation potential of bone marrow stromal cells into undifferentiated high-grade pleomorphic sarcoma. J Canc Res Clin Oncol 136: 829-838, 2010.
16. Chabannes D, Hill M, Merieau E, Rossignol J, Brion R, Soulillou JP, Anegon I and Cuturi CM: A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells. Blood 110: 3691-3694, 2007.