Effect of ECRG2 in combination with cisplatin on the proliferation and apoptosis of EC9706 cells

Experimental and Therapeutic Medicine

Volumn 8, Issue 5, 2014, Pages 1484-1488

  Song, Hai Yan ^a   Deng, Xiao Hui ^a   Hou, Xin Fang ^b   Yuan, Guo Yan ^c   Zhu, Zhen Dong ^a   Ren, Ming Xin ^a  

^a XINXIANG MEDICAL UNIVERSITY   (China)

^b ZHENGZHOU UNIVERSITY   (China)

^c The Third Hospital of Xinxiang Medical University   (China)

Author keywords

Apoptosis; Bcl 2 associated X protein; Cisplatin; Esophageal cancer related gene 2; Proliferation

Indexed keywords

CISPLATIN; ESOPHAGEAL CANCER RELATED GENE 2 PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTEIN; PROTEIN BAX; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVITY; ESOPHAGUS CANCER; FLUORESCENCE MICROSCOPE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

EID: 84907842197     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.1972     Document Type: Article

References (19)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin 61: 69-90, 2011.
2. Kollarova H, Machova L, Horakova D, Janoutova G and Janout V: Epidemiology of esophageal cancer - an overview article. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 151: 17-20, 2007.
3. Ilson DH: Esophageal cancer chemotherapy: recent advances. Gastrointest Cancer Res 2: 85-92, 2008.
4. Sjoquist KM, Burmeister BH, Smithers BM, et al: Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis. Lancet Oncol 12: 681-692, 2011.
5. van Hagen P, Hulshof MC, van Lanschot JJ, et al: Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med 366: 2074-2084, 2012.
6. Wheate NJ, Walker S, Craig GE and Oun R: The status of platinum anticancer drugs in the clinic and in clinical trials. Dalton Trans 39: 8113-8127, 2010.
7. Ando N, Kato H, Igaki H, et al: A randomized trial comparing postoperative adjuvant chemotherapy with cisplatin and 5-fluorouracil versus preoperative chemotherapy for localized advanced squamous cell carcinoma of the thoracic esophagus (JCOG9907). Ann Surg Oncol 19: 68-74, 2012.
8. Su T, Liu H and Lu S: Cloning and identification of cDNA fragments related to human esophageal cancer. Zhonghua Zhong Liu Za Zhi 20: 254-257, 1998 (In Chinese).
9. Cui Y, Wang J, Zhang X, et al: ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis. Biochem Biophys Res Commun 302: 904-915, 2003.
10. Li MN, Huang G, Guo LP and Lu SH: Inhibitory effects of esophageal cancer related gene 2 on proliferation of human esophageal cancer cell EC9706. Zhonghua Yi Xue Za Zhi 85: 2785-2788, 2005 (In Chinese).
11. Song HY, Deng XH, Yuan GY, et al: Expression of bcl-2 and p53 in induction of esophageal cancer cell apoptosis by ECRG2 in combination with cisplatin. Asian Pac J Cancer Prev 15: 1397-1401, 2014.
12. Tanaka T, Ishiguro H, Kuwabara Y, et al: Vascular endothelial growth factor C (VEGF-C) in esophageal cancer correlates with lymph node metastasis and poor patient prognosis. J Exp Clin Cancer Res 29: 83, 2010.
13. Pasetto LM, D'Andrea MR, Brandes AA, Rossi E and Monfardini S: The development of platinum compounds and their possible combination. Crit Rev Oncol Hematol 60: 59-75, 2006.
14. Yue CM, Bi MX, Tan W, et al: Short tandem repeat polymorphism in a novel esophageal cancer-related gene (ECRG2) implicates susceptibility to esophageal cancer in Chinese population. Int J Cancer 108: 232-236, 2004.
15. Song H, Song C, Wang H, et al: Suppression of hepatocarcinoma model in vitro and in vivo by ECRG2 delivery using adenoviral vector. Cancer Gene Ther 19: 875-879, 2012.
16. Tan TT and White E: Therapeutic targeting of death pathways in cancer: mechanisms for activating cell death in cancer cells. Adv Exp Med Biol 615: 81-104, 2008.
17. Qiu Y, Zou YB, Li K, et al: Effect of altered WIG-1 expression on DDP sensitivity in a DDP-resistant esophageal squamous cancer cell line. Curr Cancer Drug Targets 12: 950-961, 2012.
18. Ismail N, Pihie AH and Nallapan M: Xanthorrhizol induces apoptosis via the up-regulation of bax and p53 in HeLa cells. Anticancer Res 25: 2221-2227, 2005.
19. Wu W, Zheng Y, Wang R, et al: Antitumor activity of folate-targeted, paclitaxel-loaded polymeric micelles on a human esophageal EC9706 cancer cell line. Int J Nanomedicine 7: 3487-3502, 2012.