Lgg4 immunostaining and its implications in orbital inflammatory disease

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Wong, Amanda J ^a   Planck, Stephen R ^a,b   Choi, Dongseok ^a,c   Harrington, Christina A ^c   Troxell, Megan L ^a   Houghton, Donald C ^a   Stauffer, Patrick ^a   Wilson, David J ^a   Grossniklaus, Hans E ^d   Dailey, Roger A ^a   Ng, John D ^a   Steele, Eric A ^a   Harris, Gerald J ^e   Czyz, Craig ^f   Foster, Jill A ^g   White, Valerie A ^h   Dolman, Peter J ^h   Kazim, Michael ⁱ   Patel, Payai J ⁱ   Edward, Deepak P ^j   Katan, Hind Al ^j   Hussain, Hailah Al ^j   Selva, Dinesh ^k   Yeatts, R Patrick ^l   Korn, Bobby S ^m   Kikkawa, Don O ^m   Rosenbaum, James T ⁿ   more..

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b DEVERS EYE INSTITUTE   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

^f OHIO UNIVERSITY   (United States)

^g OHIO STATE UNIVERSITY   (United States)

^h UNIVERSITY OF BRITISH COLUMBIA   (Canada)

ⁱ Division of Ophthalmology Ohio University ^*  (United States)

^j KING KHALED EYE SPECIALIST HOSPITAL   (Saudi Arabia)

^k ROYAL ADELAIDE HOSPITAL   (Australia)

^l WAKE FOREST SCHOOL OF MEDICINE   (United States)

^m UNIVERSITY OF CALIFORNIA   (United States)

ⁿ Ophthalmology Network Royal Adelaide Hospital ^*

more..

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECANASE 1; ALPHA4 INTEGRIN; BETA6 INTEGRIN; CD22 ANTIGEN; CD28 ANTIGEN; CHEMOKINE RECEPTOR CXCR2; COLLAGEN TYPE 6; CXCL13 CHEMOKINE; CYTOGLOBIN; DISHEVELLED 2; EARLY GROWTH RESPONSE FACTOR 1; FAS ANTIGEN; FC RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; INTERFERON REGULATORY FACTOR 4; LOW DENSITY LIPOPROTEIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MUCIN 5AC; NUCLEAR RECEPTOR RELATED FACTOR 1; PER1 PROTEIN; POLYCOMB GROUP PROTEIN; PREDNISONE; RING FINGER PROTEIN; SPECTRIN; TENSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ADIPOSE TISSUE; ADULT; AGED; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENDOCRINE OPHTHALMOPATHY; EYE BIOPSY; FEMALE; GENE EXPRESSION; GRANULOMATOSIS; GRANULOMATOSIS WITH POLYANGIITIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LACRIMAL GLAND; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MICROSCOPIC POLYANGIITIS; ORBIT INFLAMMATION; PLASMA CELL; PREVALENCE; RNA EXTRACTION; RNA TRANSCRIPTION; SARCOIDOSIS; SYSTEMIC DISEASE; AUTOIMMUNE DISEASE; EYE DISEASE; IMMUNOLOGY; LACRIMAL APPARATUS; METABOLISM; MIDDLE AGED; ORBIT; PATHOLOGY; PROCEDURES;

ADULT; AGED; AUTOIMMUNE DISEASES; EYE DISEASES; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; LACRIMAL APPARATUS; MALE; MIDDLE AGED; ORBIT;

EID: 84907841722     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109847     Document Type: Article

References (32)

1. Hamano H, Kawa S, Horiuchi A, Unno H, Furuya N, et al. (2001) High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med 344: 732-738.
2. Kamisawa T, Funata N, Hayashi Y, Eishi Y, Koike M, et al. (2003) A new clinicopathological entity of IgG4-related autoimmune disease. J Gastroenterol 38: 982-984.
3. Hamed G, Tsushima K, Yasuo M, Kubo K, Yamazaki S, et al. (2007) Inflammatory lesions of the lung, submandibular gland, bile duct and prostate in a patient with IgG4-associated multifocal systemic fibrosclerosis. Respirology 12: 455 -457.
4. Cornell LD, Chicano SL, Deshpande V, Collins AB, Selig MK, et al. (2007) Pseudotumors due to IgG4 immune-complex tubulointerstitial nephritis associated with autoimmune pancreatocentric disease. Am J Surg Pathol 31: 1586-1597.
5. Zen Y, Kitagawa S, Minato H, Kurumaya H, Katayanagi K, et al. (2005) IgG4positive plasma cells in inflammatory pseudotumor (plasma cell granuloma) of the lung. Hum Pathol 36: 710-717.
6. Khosroshahi A, Carruthers MD, Deshpande V, Leb L, Reed JI, et al. (2011) Cutaneous immunoglobulin G4-related systemic disease. Am J Med 124: e7-8.
7. Sato Y, Ohshima K, Ichimura K, Sato M, Yamadori I, et al. (2008) Ocular adnexal IgG4-related disease has uniform clinicopathology. Pathol Int 58: 465 -470.
8. Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, et al. (2012) Consensus statement on the pathology of IgG4-related disease. Mod Pathol 25: 1181-1192.
9. Stone JH (2012) IgG4-related disease: nomenclature, clinical features, and treatment. Semin Diagn Pathol 29: 177-190.
10. Andrew N, Kearney D, Selva D (2013) IgG4-related orbital disease: a metaanalysis and review. Acta Ophthalmol 91: 694-700.
11. Cheuk W, Yuen HK, Chan JK (2007) Chronic sclerosing dacryoadenitis: part of the spectrum of IgG4-related Sclerosing disease? Am J Surg Pathol 31: 643-645.
12. Wallace ZS, Khosroshahi A, Jakobiec FA, Deshpande V, Hatton MP, et al. (2012) IgG4-related systemic disease as a cause of "idiopathic" orbital inflammation, including orbital myositis, and trigeminal nerve involvement. Surv Ophthalmol 57: 26-33.
13. Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, et al. (2012) Consensus statement on the pathology of IgG4-related disease. Mod Pathol 25: 1181-1192.
14. Stone JH, Khosroshahi A, Deshpande V, Chan JK, Heathcote JG, et al. (2012) Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis Rheum 64: 3061-3067.
15. Rispens T, Ooievaar-De Heer P, Vermeulen E, Schuurman J, van der Neut Kolfschoten M, et al. (2009) Human IgG4 binds to IgG4 and conformationally altered IgGl via Fc-Fc interactions. J Immunol 182: 4275-4281.
16. van de Stadt LA, de Vrieze H, Derksen NI, Brouwer M, Wouters D, et al. (2013) Antibodies to IgG4 hinge can be found in Rheumatoid Arthritis patients during all stages of disease and may exacerbate chronic antibody-mediated inflammation. Arthritis Rheum.
17. Karamchandani JR, Younes SF, Warnke RA, Natkunam Y (2012) IgG4-related systemic sclerosing disease of the ocular adnexa: a potential mimic of ocular lymphoma. Am J Clin Pathol 137: 699-711.
18. Plaza JA, Garrity JA, Dogan A, Ananthamurthy A, Witzig TE, et al. (2011) Orbital inflammation with IgG4-positive plasma cells: manifestation of IgG4 systemic disease. Arch Ophthalmol 129: 421-428.
19. Khosroshahi A, Bloch DB, Deshpande V, Stone JH (2010) Rituximab therapy leads to rapid decline of serum IgG4 levels and prompt clinical improvement in IgG4-related systemic disease. Arthritis Rheum 62: 1755-1762.
20. Khosroshahi A, Carruthers MN, Deshpande V, Unizony S, Bloch DB, et al.
21. Rituximab for the treatment of IgG4-related disease: lessons from 10 consecutive patients. Medicine (Baltimore) 91: 57-66.
22. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, et al. (2003) Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 31: el5.
23. Lehman JS, Smyrk TC, Pittelkow MR (2014) Increased immunoglobulin (Ig) G4-positive plasma cell density and IgG4/IgG ratio are not specific for IgG4related disease in the skin. Am J Clin Pathol 141: 234-238.
24. Wallace ZS, Carruthers MN, Khosroshahi A, Carruthers R, Shinagare S, et al. (2013) IgG4-related disease and hypertrophic pachymeningitis. Medicine (Baltimore) 92: 206-216.
25. Strehl JD, Hartmann A, Agaimy A (2011) Numerous IgG4-positive plasma cells are ubiquitous in diverse localised non-specific chronic inflammatory conditions and need to be distinguished from IgG4-related systemic disorders. J Clin Pathol 64: 237-243.
26. Japanese study group of Ig Grod (2013) A prevalence study of IgG4-related ophthalmic disease in Japan. JpnJ Ophthalmol 57: 573-579.
27. Chang SY, Keogh KA, Lewis JE, Ryu JH, Cornell LD, et al. (2013) IgG4positive plasma cells in granulomatosis with polyangiitis (Wegener's): a clinicopathologic and immunohistochemical study on 43 granulomatosis with polyangiitis and 20 control cases. Hum Pathol 44: 2432-2437.
28. Houghton DC, Troxell ML (2011) An abundance of IgG4+ plasma cells is not specific for IgG4-related tubulointerstitial nephritis. Mod Pathol 24: 1480-1487.
29. Mehta M, Jakobiec F, Fay A (2009) Idiopathic fibroinflammatory disease of the face, eyelids, and periorbital membrane with immunoglobulin G4-positive plasma cells. Arch Pathol Lab Med 133: 1251-1255.
30. Lindfield D, Attfield K, McElvanney A (2012) Systemic immunoglobulin G4 (IgG4) disease and idiopathic orbital inflammation; removing 'idiopathic' from the nomenclature? Eye (Lond) 26: 623-629.
31. Matsuo T, Ichimura K, Sato Y, Tanimoto Y, Kiura K, et al. (2010) Immunoglobulin G4 (IgG4)-positive or -negative ocular adnexal benign lymphoid lesions in relation to systemic involvement. J Clin Exp Hematop 50: 129-142.
32. Suhler EB, Lim LL, Beardsley RM, Giles TR, Pasadhika S, et al. (2014) Rituximab therapy for refractory orbital inflammation: results of a phase 1/2 dose-ranging, randomized clinical trial. JAMA Ophthalmology: 572-578.