Nanoparticle encapsidation of Flock House virus by auto assembly of Tobacco Mosaic virus coat protein

International Journal of Molecular Sciences

Volumn 15, Issue 10, 2014, Pages 18540-18556

  Maharaj, Payal D ^a   Mallajosyula, Jyothi K ^a   Lee, Gloria ^a   Thi, Phillip ^a   Zhou, Yiyang ^b   Kearney, Christopher M ^b   McCormick, Alison A ^a  

^a TOURO UNIVERSITY CALIFORNIA   (United States)

^b BAYLOR UNIVERSITY   (United States)

Author keywords

Encapsidation; Flock House virus; Nanoparticle; Self assembly; Tobacco Mosaic virus; Transgene expression; Viral vector

Indexed keywords

COAT PROTEIN; NANOPARTICLE; VIRUS RNA; CAPSID PROTEIN; GREEN FLUORESCENT PROTEIN;

AGAR GEL ELECTROPHORESIS; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLOCK HOUSE VIRUS; FLUORESCENCE IMAGING; GENE EXPRESSION; GENETIC TRANSFECTION; IN VITRO STUDY; NODAVIRUS; NONHUMAN; PROTEIN EXPRESSION; TOBACCO MOSAIC VIRUS; TRANSGENE; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS GENE; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMISTRY; GENE VECTOR; GENETICS; HAMSTER; NODAVIRIDAE;

FLOCK HOUSE VIRUS; TOBACCO MOSAIC VIRUS;

ANIMALS; CAPSID; CAPSID PROTEINS; CELL LINE; CRICETINAE; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; NANOPARTICLES; NODAVIRIDAE; RNA, VIRAL; TOBACCO MOSAIC VIRUS; TRANSFECTION;

EID: 84907834015     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms151018540     Document Type: Article

References (38)

1. Fraenkel-Conrat, H.; Williams, C. R. Reconstitution of active Tobacco Mosaic virus from its inactive protein and nucleic acid components. Proc. Natl. Acad. Sci. USA 1955, 41, 690-698.
2. Butler, P. J. G. Self-assembly of Tobacco Mosaic virus: The role of an intermediate aggregate in generating both specificity and speed. Philos. Trans. R. Soc. B Biol. Sci. 1999, 354, 537-550.
3. Turner, D. R.; Joyce, L. E.; Butler, P. J. G. The Tobacco Mosaic virus assembly origin RNA: Functional characteristics defined by directed mutagenesis. J. Mol. Biol. 1988, 203, 531-547.
4. Gallie, D. R.; Sleat, D. E.; Watts, J. W.; Turner, P. C.; Wilson, T. M. A. In vivo uncoating and efficient expression of foreign mrnas packaged in tmv-like particles. Science 1987, 236, 1122-1124.
5. Smith, M. L.; Corbo, T.; Bernales, J.; Lindbo, J. A.; Pogue, G. P.; Palmer, K. E.; McCormick, A. A. Assembly of trans-encapsidated recombinant viral vectors engineered from Tobacco Mosaic virus and semliki forest virus and their evaluation as immunogens. Virology 2007, 358, 321-333.
6. Lindenbach, B. D.; Sgro, J. Y.; Ahlquist, P. Long-distance base pairing in Flock House virus rna1 regulates subgenomic RNA3 synthesis and RNA2 replication. J. Virol. 2002, 76, 3905-3919.
7. Annamalai, P.; Rofail, F.; DeMason, D. A.; Rao, A. L. N. Replication-coupled packaging mechanism in positive-strand RNA viruses: Synchronized coexpression of functional multigenome rna components of an animal and a plant virus in nicotiana benthamiana cells by agroinfiltration. J. Virol. 2008, 82, 1484-1495.
8. Johnson, K. L.; Ball, L. A. Induction and maintenance of autonomous Flock House virus RNA1 replication. J. Virol. 1999, 73, 7933-7942.
9. Price, B. D.; Ahlquist, P.; Ball, L. A. DNA-directed expression of an animal virus RNA for replication-dependent colony formation in saccharomyces cerevisiae. J. Virol. 2002, 76, 1610-1616.
10. Li, H.; Li, W. X.; Ding, S. W. Induction and suppression of rna silencing by an animal virus. Science 2002, 296, 1319-1321.
11. Scotti, P. D.; Dearing, S.; Mossop, D. W. Flock House virus: A nodavirus isolated fromcostelytra zealandica (white) (coleoptera: Scarabaeida). Arch. Virol. 1983, 75, 181-189.
12. Selling, B. H.; Allison, R. F.; Kaesberg, P. Genomic RNA of an insect virus directs synthesis of infectious virions in plants. Proc. Natl. Acad. Sci. USA 1990, 87, 434-438.
13. Dasgupta, R.; Garcia, B. H.; Goodman, R. M. Systemic spread of an RNA insect virus in plants expressing plant viral movement protein genes. Proc. Natl. Acad. Sci. USA 2001, 98, 4910-4915.
14. Dasgupta, R.; Selling, B.; Rueckert, R. Flock House virus: A simple model for studying persistent infection in cultured drosophila cells. Arch. Virol. Suppl. 1994, 9, 121-132.
15. Dasgupta, R.; Free, H. M.; Zietlow, S. L.; Paskewitz, S. M.; Aksoy, S.; Shi, L.; Fuchs, J.; Hu, C.; Christensen, B. M. Replication of Flock House virus in three genera of medically important insects. J. Med. Entomol. 2007, 44, 102-110.
16. Price, B. D.; Rueckert, R. R.; Ahlquist, P. Complete replication of an animal virus and maintenance of expression vectors derived from it in saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 1996, 93, 9465-9470.
17. Dasmahapatra, B.; Dasgupta, R.; Ghosh, A.; Kaesberg, P. Structure of the black beetle virus genome and its functional implications. J. Mol. Biol. 1985, 182, 183-189.
18. Singh, G.; Popli, S.; Hari, Y.; Malhotra, P.; Mukherjee, S.; Bhatnagar, R. K. Suppression of RNA silencing by Flock House virus b2 protein is mediated through its interaction with the paz domain of dicer. FASEB J. 2009, 23, 1845-1857.
19. Friesen, P. D.; Rueckert, R. R. Synthesis of black beetle virus proteins in cultured drosophila cells: Differential expression of RNAs 1 and 2. J. Virol. 1981, 37, 876-886.
20. Zhong, W.; Rueckert, R. R. Flock House virus: Down-regulation of subgenomic RNA3 synthesis does not involve coat protein and is targeted to synthesis of its positive strand. J. Virol. 1993, 67, 2716-2722.
21. Dasmahapatra, B.; Dasgupta, R.; Saunders, K.; Selling, B. H.; Gallagher, T.; Kaesberg, P. Infectious rna derived by transcription from cloned cDNA copies of the genomic RNA of an insect virus. Proc. Natl. Acad. Sci. USA 1986, 83, 63-66.
22. Ball, L. A. Cellular expression of a functional nodavirus RNA replicon from vaccinia virus vectors. J. Virol. 1992, 66, 2335-2345.
23. Price, B. D.; Roeder, M.; Ahlquist, P. DNA-directed expression of functional Flock House virus RNA1 derivatives in saccharomyces cerevisiae, heterologous gene expression, and selective effects on subgenomic mRNA synthesis. J. Virol. 2000, 74, 11724-11733.
24. Wu, S. X.; Kaesberg, P. Synthesis of template-sense, single-strand flockhouse virus RNA in a cell-free replication system. Virology 1991, 183, 392-396.
25. Fournier, C.; Helle, F.; Descamps, V.; Morel, V.; Francois, C.; Dedeurwaerder, S.; Wychowski, C.; Duverlie, G.; Castelain, S. Natural selection of adaptive mutations in non-structural genes increases trans-encapsidation of hepatitis C virus replicons lacking envelope protein genes. J. Gen. Virol. 2013, 94, 996-1008.
26. Zhong, W.; Dasgupta, R.; Rueckert, R. Evidence that the packaging signal for nodaviral RNA2 is a bulged stem-loop. Proc. Natl. Acad. Sci. USA 1992, 89, 11146-11150.
27. Seo, J. K.; Kwon, S. J.; Rao, A. L. A physical interaction between viral replicase and capsid protein is required for genome-packaging specificity in an RNA virus. J. Virol. 2012, 86, 6210-6221.
28. Schneemann, A.; Zhong, W.; Gallagher, T. M.; Rueckert, R. R. Maturation cleavage required for infectivity of a nodavirus. J. Virol. 1992, 66, 6728-6734.
29. Ball, L. A. Requirements for the self-directed replication of Flock House virus RNA 1. J. Virol. 1995, 69, 720-727.
30. Ball, L. A.; Li, Y. Cis-acting requirements for the replication of Flock House virus RNA2. J. Virol. 1993, 67, 3544-3551.
31. Dasgupta, R.; Cheng, L. L.; Bartholomay, L. C.; Christensen, B. M. Flock House virus replicates and expresses green fluorescent protein in mosquitoes. J. Gen. Virol. 2003, 84, 1789-1797.
32. Hwang, D. J.; Roberts, I. M.; Wilson, T. M. Expression of Tobacco Mosaic virus coat protein and assembly of pseudovirus particles in Escherichia coli. Proc. Natl. Acad. Sci. USA 1994, 91, 9067-9071.
33. Sleat, D. E.; Gallie, D. R.; Watts, J. W.; Deom, C. M.; Turner, P. C.; Beachy, R. N.; Wilson, T. M. A. Selective recovery of foreign gene transcripts as virus-like particles in TMV-infected transgenic tobaccos. Nucleic Acids Res. 1988, 16, 3127-3140.
34. Kadri, A.; Wege, C.; Jeske, H. In vivo self-assembly of TMV-like particles in yeast and bacteria for nanotechnological applications. J. Virol. Methods 2013, 189, 328-340.
35. Kemnade, J. O.; Seethammagari, M.; Collinson-Pautz, M.; Kaur, H.; Spencer, D. M.; McCormick, A. A. Tobacco Mosaic virus efficiently targets DC uptake, activation and antigen-specific T cell responses in vivo. Vaccine 2014, 32, 4228-4233.
36. Mallajosyula, J. K.; Hiatt, E.; Hume, S.; Johnson, A.; Jeevan, T.; Chikwamba, R.; Pogue, G. P.; Bratcher, B.; Haydon, H.; Webby, R. J.; et al. Single-dose monomeric ha subunit vaccine generates full protection from influenza challenge. Hum. Vaccines Immunother. 2014, 10, 586-595.
37. Kim, J. H.; Lee, S. R.; Li, L. H.; Park, H. J.; Park, J. H.; Lee, K. Y.; Kim, M. K.; Shin, B. A.; Choi, S. Y. High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice. PLoS One 2011, 6, e18556.
38. McCormick, A. A.; Corbo, T. A.; Wykoff-Clary, S.; Nguyen, L. V.; Smith, M. L.; Palmer, K. E.; Pogue, G. P. Tmv-peptide fusion vaccines induce cell-mediated immune responses and tumor protection in two murine models. Vaccine 2006, 24, 6414-6423.