MiR-219 inhibits the growth and metastasis of TSCC cells by targeting PRKCI

International Journal of Clinical and Experimental Medicine

Volumn 7, Issue 9, 2014, Pages 2957-2965

  Song, Kai Bin ^a   Liu, Wen Juan ^b   Jia, Shen Shan ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Growth; Metastasis; MiR 219; PRKCI; TSCC

Indexed keywords

MICRORNA; MICRORNA 219; PROTEIN KINASE C IOTA; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CELL INVASION ASSAY; CELL MIGRATION ASSAY; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUCIFERASE ASSAY; METASTASIS; MTT ASSAY; PLASMID; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SPECTROPHOTOMETRY; TONGUE CARCINOMA; TUMOR INVASION; WESTERN BLOTTING;

EID: 84907819351     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.
2. Siegel R, Naishadham D and Jemal A. Cancer statistics, 2012. CA Cancer J Clin 2012; 62: 10-29.
3. Sano D and Myers JN. Metastasis of squamous cell carcinoma of the oral tongue. Cancer Metastasis Rev 2007; 26: 645-662.
4. Xie B, Ding Q, Han H and Wu D. miRCancer: a microRNA-cancer association database constructed by text mining on literature. Bioinformatics 2013; 29: 638-644.
5. Kong W, He L, Richards EJ, Challa S, Xu CX, Permuth-Wey J, Lancaster JM, Coppola D, Sellers TA, Djeu JY and Cheng JQ. Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene 2014; 33: 679-689.
6. Majid S, Dar AA, Saini S, Shahryari V, Arora S, Zaman MS, Chang I, Yamamura S, Tanaka Y, Chiyomaru T, Deng G and Dahiya R. miRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications, and AKT pathways. Clin Cancer Res 2013; 19: 73-84.
7. Liu X, Wang A, Heidbreder CE, Jiang L, Yu J, Kolokythas A, Huang L, Dai Y and Zhou X. MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma. FEBS Lett 2010; 584: 4115-4120.
8. Jia LF, Wei SB, Gan YH, Guo Y, Gong K, Mitchelson K, Cheng J and Yu GY. Expression, regulation and roles of miR-26a and MEG3 in tongue squamous cell carcinoma. Int J Cancer 2013; [Epub ahead of print].
9. Lahdaoui F, Delpu Y, Vincent A, Renaud F, Messager M, Duchene B, Leteurtre E, Mariette C, Torrisani J, Jonckheere N and Van Seuningen I. miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer. Oncogene 2014; 0: 1-9.
10. Rao SA, Arimappamagan A, Pandey P, Santosh V, Hegde AS, Chandramouli BA and Somasundaram K. miR-219-5p inhibits receptor tyrosine kinase pathway by targeting EGFR in glioblastoma. PLoS One 2013; 8: e63164.
11. Huang N, Lin J, Ruan J, Su N, Qing R, Liu F, He B, Lv C, Zheng D and Luo R. MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3. FEBS Lett 2012; 586: 884-891.
12. Lei H, Zou D, Li Z, Luo M, Dong L, Wang B, Yin H, Ma Y, Liu C, Wang F, Zhang J, Yu J and Li Y. MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation. PLoS One 2013; 8: e60369.
13. Zhou B, Chen H, Wei D, Kuang Y, Zhao X, Li G, Xie J and Chen P. A novel miR-219-SMC4-JAK2/Stat3 regulatory pathway in human hepatocellular carcinoma. J Exp Clin Cancer Res 2014; 33: 55.
14. Fields AP and Regala RP. Protein kinase C iota: human oncogene, prognostic marker and therapeutic target. Pharmacol Res 2007; 55: 487-497.
15. Regala RP, Weems C, Jamieson L, Khoor A, Edell ES, Lohse CM and Fields AP. Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer. Cancer Res 2005; 65: 8905-8911.
16. Campa D, Canzian F and Kaaks R. Genetic variability in the PRKCI gene and prostate cancer risk. Cell Cycle 2012; 11: 209.
17. Yang YL, Chu JY, Luo ML, Wu YP, Zhang Y, Feng YB, Shi ZZ, Xu X, Han YL, Cai Y, Dong JT, Zhan QM, Wu M and Wang MR. Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma. Genes Chromosomes Cancer 2008; 47: 127-136.
18. Frederick LA, Matthews JA, Jamieson L, Justilien V, Thompson EA, Radisky DC and Fields AP. Matrix metalloproteinase-10 is a critical effector of protein kinase Ciota-Par6alpha-mediated lung cancer. Oncogene 2008; 27: 4841-4853.
19. Justilien V and Fields AP. Ect2 links the PKCiota-Par6alpha complex to Rac1 activation and cellular transformation. Oncogene 2009; 28: 3597-3607.
20. Regala RP, Weems C, Jamieson L, Copland JA, Thompson EA and Fields AP. Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity. J Biol Chem 2005; 280: 31109-31115.
21. Justilien V, Walsh MP, Ali SA, Thompson EA, Murray NR and Fields AP. The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma. Cancer Cell 2014; 25: 139-151.