A novel mouse model for Down syndrome that harbor a single copy of human artificial chromosome (HAC) carrying a limited number of genes from human chromosome 21.

Transgenic research

Volumn 23, Issue 2, 2014, Pages 317-329

  Miyamoto, Kenichi ^a   Suzuki, Nobutaka ^b   Sakai, Kosuke ^b   Asakawa, Shuichi ^b   Okazaki, Tsuneko ^b   Kudoh, Jun ^b   Ikeno, Masashi ^b   Shimizu, Nobuyoshi ^b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; CHROMOSOME 21; CROSS BREEDING; DISEASE MODEL; DOWN SYNDROME; EMBRYONIC STEM CELL; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DOSAGE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; HUMAN ARTIFICIAL CHROMOSOME; METABOLISM; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENE;

ANIMALS; CHROMOSOMES, ARTIFICIAL, HUMAN; CHROMOSOMES, HUMAN, PAIR 21; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; DOWN SYNDROME; EMBRYONIC STEM CELLS; GENE DOSAGE; GENE EXPRESSION PROFILING; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSGENES;

EID: 84907811821     PISSN: None     EISSN: 15739368     Source Type: Journal    
DOI: 10.1007/s11248-013-9772-x     Document Type: Article

References (0)