Prognostic value and staging classification of retropharyngeal lymph node metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiotherapy

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Tang, Ling Long ^a   Guo, Rui ^a   Zhou, Guanqun ^a   Sun, Ying ^a   Liu, Li Zhi ^a   Lin, Ai Hua ^b   Mai, Haiqiang ^a   Shao, Jianyong ^a   Li, Li ^a   Ma, Jun ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER PATIENT; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER STAGING; DISEASE FREE SURVIVAL; DISTANT METASTASIS FREE SURVIVAL; FEMALE; HUMAN; INCIDENCE; INTENSITY MODULATED RADIATION THERAPY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NASOPHARYNX CARCINOMA; RETROPHARYNGEAL LYMPH NODE METASTASIS; RETROSPECTIVE STUDY; SURVIVAL RATE; COHORT ANALYSIS; LYMPH NODE; LYMPHATIC METASTASIS; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; NEOPLASM RECURRENCE, LOCAL; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PHARYNX; PROGNOSIS;

COHORT STUDIES; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PHARYNX; PROGNOSIS; RADIOTHERAPY, INTENSITY-MODULATED; RETROSPECTIVE STUDIES;

EID: 84907811064     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108375     Document Type: Article

References (28)

1. Parkin DM, Whelan SL, Ferlay J, Raymond L, Young J (1997) Cancer incidence in five continents. IARC, Lyon France, 143: 814-815.
2. Sham JST, Choy D, Wei WI (1990) Nasopharyngeal carcinoma: orderly neck node spread. Int J Radiat Oncol Biol Phys 19: 929-933.
3. Ng SH, Chang TC, Ko SF, Yen PS, Wan YL, et al. (1997) Nasopharyngeal carcinoma: MRI and CT assessment. Neuroradiology 39: 741-746.
4. Olmi P, Fallai C, Colagrande S, Giannardi G (1995) Staging and follow-up of nasopharyngeal carcinoma: magnetic resonance imaging versus computerized tomography. Int J Radiat Oncol Biol Phys 32: 795-800.
5. Liao XB, Mao YP, Liu LZ, Tang LL, Sun Y, et al. (2008) How does magnetic resonance imaging influence staging according to AJCC staging system for nasopharyngeal carcinoma compared with computed tomography? Int J RadiatOncolBiol Phys 72: 1368-1377.
6. Ng SH, Chang JT, Chan SC, Ko SF, Wang HM, et al. (2004) Nodal metastases of nasopharyngeal carcinoma: patterns of disease on MRI and FDG-PET. Eur J Nucl Med Mol Imaging 31: 1073-1080.
7. Ma J, Liu L, Tang L, Zong J, LinA, et al. (2007) Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma: prognostic value and staging categories. Clin Cancer Res 13: 1445-152.
8. Edge SB, Fritz AG, Byrd DR, Greene FL, Compton CC, et al. (2010) AJCC cancer staging manual. Springer, Berlin Heidelberg New York, 41-56.
9. Lai SZ, Li WF, Chen L, Luo W, Chen YY, et al. (2011) How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients? Int J Radiat Oncol Biol Phys 80: 661-668.
10. Van den Brekel MW, Castelijns JA, Snow GB (1990) Cervical lymph node metastasis: Assessment of radiologic criteria. Radiology 177: 379-384.
11. Lam WW, Chan YL, Leung SF, Metreweli C (1997) Retropharyngeal lymphadenopathy in nasopharyngeal carcinoma. Head Neck 19: 176-181
12. King AD, Tse GM, Ahuja AT, Yuen EH, Vlantis AC, et al. (2004) Necrosis in metastatic neck nodes: Diagnostic accuracy of CT, MR imaging, and US. Radiology 230: 720-726.
13. King AD, Tse GM, Yuen EH, To EW, Vlantis AC, et al.(2004) Comparison of CT and MR imaging for the detection of extranodal neoplastic spread in metastatic neck nodes. Eur J Radiol 52: 264-70.
14. Kaplan EL, Meier P (1958) Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association. 53: 457-481.
15. Cox DR (1972) Regression Models and Life-Tables. Journal of the Royal Statistical Society. Series B (Methodological). 34: 187-220.
16. Groome PA, Schulze K, Boysen M, Hall SF, Mackillop WJ (2001) A comparison of published head and neck stage groupings in carcinomas of the oral cavity. Head Neck 23: 613-624.
17. Ng WT, Lee MC, Hung WM, Choi CW, Lee KC, et al. (2011) Clinical outcomes and patterns of failure after intensity-modulated radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 79: 420-428.
18. Xia P, Fu KK, Wong GW, Akazawa C, Verhey LJ (2000) Comparison of treatment plans involving intensity-modulated radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 48: 329-337.
19. Sham JST, Choy D, Wei WI (1990) Nasopharyngeal carcinoma: orderly neck node spread. Int J Radiat Oncol Biol Phys 19: 929-933.
20. Tang L, Mao Y, Liu L, Liang SB, Chen Y, et al. (2009) The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma: analysis of the spread patterns in lymph nodes by magnetic resonance imaging. Cancer 115: 680-688.
21. King AD, Ahuja AT, Leung SF, Lam WW, Teo P, et al. (2000) Neck node metastases from nasopharyngeal carcinoma: MR imaging of patterns of disease. Head Neck 22: 275-281.
22. Kong F, Ying H, Huang S, Du C, Zhou J, et al. (2014) Preliminary results of nasopharyngeal carcinoma treated with intensity-modulated radiotherapy: a retrospective study of 364 patients. Eur Arch Otorhinolaryngol DOI 10.1007/s00405-014-2900-2. In press.
23. Som P (1987) Lymph nodes of the neck. Radiology 165: 593-600.
24. Don DM, Anzai Y, Lufkin RB, Fu YS, Calcaterra TC (1995) Evaluation of cervical lymph node metastases in squamous cell carcinoma of the head and neck. Laryngoscope 105: 669-674.
25. Rischin D, Hicks RJ, Fisher R, Binns D, Corry J, et al. (2006) Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: a substudy of Trans-Tasman Radiation Oncology Group Study 98.02. J Clin Oncol 24: 2098-2104.
26. Toustrup K, Sorensen BS, Lassen P, Wiuf C, Alsner J, et al. (2012) Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck. Radiother Oncol 102: 122-129.
27. Toustrup K, Sorensen BS, Nordsmark M, Busk M, Wiuf C, et al. (2011) Development of a hypoxia gene expression classifier with predictive impact for hypoxic modification of radiotherapy in head and neck cancer. Cancer Res 71: 5923-5931.
28. Tang L, Li L, Mao Y, Liu LZ, Liang SB, et al. (2008) Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma detected by magnetic resonance imaging: prognostic value and staging categories. Cancer 113: 347-354.