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Volumn 5, Issue 10, 2014, Pages 1555-1562
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Design, synthesis and molecular docking of novel bipyrazolyl thiazolone scaffold as a new class of antibacterial agents
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Author keywords
[No Author keywords available]
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Indexed keywords
2 [3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H(3,4' BIPYRAZOLE) 2 YL ] THIAZOL 4(5H) ONE;
2 [3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 5, (1H 1,2,4 TRIAZOL 1 YL) 3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL]5 (THIOPHEN 2 YLMETHYLENE)THIAZOL 4(5H) ONE;
2 [5' (1H BENZO[D]IMIDAZOL 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL] 5 (FURAN 2 YLMETHYLENE)THIAZOL 4 (5H) ONE;
2 [5' (1H BENZO[D]IMIDAZOL1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL] 5 (THIOPHEN 2 YLMETHYLENE)THIAZOL 4 (5H) ONE;
2 [5' (1H BENZO[D][1,2,3]TRIAZOL 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL] 5 (FURAN 2 YLMETHYLENE)THIAZOL 4 (5H) ONE;
2 [5' (1H BENZO[D][1,2,3]TRIAZOL 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL] 5 (THIOPHEN 2 YLMETHYLENE)THIAZOL 4 (5H) ONE;
2 [5' (1H IMIDAZOL 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL] 5 (FURAN 2 YLMETHYLENE)THIAZOL 4 (5H) ONE;
2 [5' (1H IMIDAZOL 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL] 5 (THIOPHEN 2 YLMETHYLENE)THIAZOL 4 (5H) ONE;
3 (3 METHYL 1 PHENYL 1H PYRAZOL 4 YL) 1 (THIOPHEN 2 YL)PROP 2 EN 1 ONE DERIVATIVE;
3 METHYL 1 PHENYL 5 (1H 1,2,4 TRIAZOL 1 YL) 1H PYRAZOLE 4 CARBALDEHYDE;
3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H[3,4' BIPYRAZOLE] 2 CARBOTHIOAMIDE;
5 (1H BENZO[D]IMIDAZOL 1 YL) 3 METHYL 1 PHENYL 1H PYRAZOLE 4 CARBALDEHYDE;
5 (1H BENZO[D][1,2,3,]IMIDAZOL 1 YL) 3 METHYL 1 PHENYL 1H PYRAZOLE 4 CARBALDEHYDE;
5 (1H IMIDAZOL 1 YL) 3 METHYL 1 PHENYL 1H PYRAZOLE 4 CARBALDEHYDE;
5 (FURAN 2 YLMETHYLENE) 2 (3,4 DIHYDRO 1'H,2H [3,4' BIPYRAZOL] 2 YL)THIAZOL 4(5H) ONE;
5 (HETEROARYL) 3 METHYL 1 PHENYL 1H PYRAZOLE 4 CARBALDEHYDE;
5 [(1H BENZO[D]IMIDAZOL 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4 BIPYRAZOL] 2 YL] 5 [(1H INDOL 3 YL)METHYLENE]THIAZOL 4(5H) ONE;
5 [(1H BENZO[D][1,2,3]TRIAZOL 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4 BIPYRAZOL] 2 YL] 5 [(1H INDOL 3 YL)METHYLENE]THIAZOL 4(5H) ONE;
5 [(1H IMIDAZOLE 1 YL) 3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H [3,4 BIPYRAZOL] 2 YL] 5 [(1H INDOL 3 YL)METHYLENE]THIAZOL 4(5H) ONE;
5 [(1H INDOL 3 YL)METHYLENE] 2 [3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO 1'H,2H[3,4' BIPYRAZOL] 2 YL] THIAZOL 4 (5H) ONE;
5 [(1H INDOL 3 YL)METHYLENE] 2 [3' METHYL 1' PHENYL 5 (THIOPHEN 2 YL) 3,4 DIHYDRO1'H,2H[3,4' BIPYRAZOL] 2 YL] 5 [(1H INDOL 3 YL)METHYLENE]THIAZOL 4(5H) ONE;
ANTIINFECTIVE AGENT;
BENZIMIDAZOLE;
BIPYRAZOLYL THIAZOLONE;
IMIDAZOLE;
KANAMYCIN B;
PENICILLIN G;
TRIAZOLE;
UNCLASSIFIED DRUG;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
DRUG DESIGN;
DRUG SYNTHESIS;
ESCHERICHIA COLI;
GRAM NEGATIVE BACTERIUM;
GRAM POSITIVE BACTERIUM;
HYDROGEN BOND;
IC50;
IN VITRO STUDY;
MOLECULAR DOCKING;
MOLECULAR HYBRIDIZATION;
SPECTROSCOPY;
STRUCTURE ACTIVITY RELATION;
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EID: 84907811028
PISSN: 20402503
EISSN: 20402511
Source Type: Journal
DOI: 10.1039/c4md00238e Document Type: Article |
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Times cited : (35)
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References (40)
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