The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines

Cancer medicine

Volumn 3, Issue 1, 2014, Pages 36-46

  Stratford, Eva W essel ^a   Daffinrud, Jeanette ^a   Munthe, Else ^a   Castro, Russell ^a   Waaler, Jo ^a   Krauss, Stefan ^a   Myklebost, Ola ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Differentiation; JW74; let 7; osteosarcoma; tankyrase; TNKS inhibitior; Wnt; catenin

Indexed keywords

ANTINEOPLASTIC AGENT; AXIN; JW74 COMPOUND; OXADIAZOLE DERIVATIVE; TANKYRASE; TNKS PROTEIN, HUMAN; TRIAZOLE DERIVATIVE;

ANTAGONISTS AND INHIBITORS; APOPTOSIS; BONE DEVELOPMENT; BONE NEOPLASMS; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; HUMAN; OSTEOSARCOMA; PATHOLOGY; TUMOR CELL LINE; WNT SIGNALING PATHWAY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AXIN SIGNALING COMPLEX; BONE NEOPLASMS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; OSTEOGENESIS; OSTEOSARCOMA; OXADIAZOLES; TANKYRASES; TRIAZOLES; WNT SIGNALING PATHWAY;

EID: 84907659517     PISSN: None     EISSN: 20457634     Source Type: Journal    
DOI: 10.1002/cam4.170     Document Type: Article

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