ALK-positive inflammatory myofibroblastic tumor of the abdomen with widespread microscopic multifocality

International Journal of Surgical Pathology

Volumn 22, Issue 7, 2014, Pages 640-644

  Lorenzi, Luisa ^a   Cigognetti, Marta ^a   Medicina, Daniela ^a   Pellegrini, Vilma ^a   Balzarini, Piera ^a   Cestari, Renzo ^a   Facchetti, Fabio ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

ALK; inflammatory myofibroblastic tumor; microscopic multifocality; omentum

Indexed keywords

CRIZOTINIB; ANAPLASTIC LYMPHOMA KINASE; ONCOPROTEIN; ONCOPROTEIN CLTCL-ALK; PROTEIN TYROSINE KINASE; TUMOR MARKER;

ABDOMINAL TUMOR; ADULT; ARTICLE; BILIARY TRACT DRAINAGE; CASE REPORT; CLTC ALK FUSION GENE; COLON; COMPUTER ASSISTED TOMOGRAPHY; FINE NEEDLE ASPIRATION BIOPSY; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; JAUNDICE; LAPAROSCOPY; LIVER; MALE; MESOTHELIUM; MYOFIBROBLAST; NUCLEAR MAGNETIC RESONANCE IMAGING; OMENTECTOMY; OMENTUM; PLASMA CELL GRANULOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINDLE CELL; SURGICAL APPROACH; TUMOR NECROSIS; YOUNG ADULT; BIOSYNTHESIS; COLON TUMOR; GENETICS; LIVER TUMOR; MUSCLE TUMOR; PATHOLOGY; SECONDARY;

ABDOMINAL NEOPLASMS; BIOMARKERS, TUMOR; COLONIC NEOPLASMS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LIVER NEOPLASMS; MALE; NEOPLASMS, MUSCLE TISSUE; OMENTUM; ONCOGENE PROTEINS, FUSION; RECEPTOR PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84907630427     PISSN: 10668969     EISSN: 19402465     Source Type: Journal    
DOI: 10.1177/1066896914525232     Document Type: Article

References (24)

1. Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F WHO Classification of Tumours of Soft Tissue and Bone. 4 th ed.Lyon, France: IARC Press; 2013. Lyon, France: IARC Press ; 2013 :
2. Coffin CM, Watterson J, Priest JR, Dehner LP. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). A clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol. 1995 ; 19: 859-872
3. Coffin CM, Patel A, Perkins S, Elenitoba-Johnson KS, Perlman E, Griffin CA. ALK1 and p80 expression and chromosomal rearrangements involving 2p23 in inflammatory myofibroblastic tumor. Mod Pathol. 2001 ; 14: 569-576
4. Su LD, Atayde-Perez A, Sheldon S, Fletcher JA, Weiss SW. Inflammatory myofibroblastic tumor: cytogenetic evidence supporting clonal origin. Mod Pathol. 1998 ; 11: 364-368
5. Chan JK, Cheuk W, Shimizu M. Anaplastic lymphoma kinase expression in inflammatory pseudotumors. Am J Surg Pathol. 2001 ; 25: 761-768
6. Cook JR, Dehner LP, Collins MH, et al. Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study. Am J Surg Pathol. 2001 ; 25: 1364-1371
7. Lawrence B, Perez-Atayde A, Hibbard MK, et al. TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. Am J Pathol. 2000 ; 157: 377-384
8. Marino-Enriquez A, Wang WL, Roy A, et al. Epithelioid inflammatory myofibroblastic sarcoma: an aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. Am J Surg Pathol. 2011 ; 35: 135-144
9. Vermi W, Lonardi S, Morassi M, et al. Cutaneous distribution of plasmacytoid dendritic cells in lupus erythematosus. Selective tropism at the site of epithelial apoptotic damage. Immunobiology. 2009 ; 214: 877-886
10. Gatta LB, Incardona P, Cadei M, Grigolato P, Simoncelli S, Balzarini P. Simultaneous fluorescence immunophenotyping and Her-2/neu genotyping (FICTION) in breast carcinoma candidates to target therapy. Appl Immunohistochem Mol Morphol. 2012 ; 20: 413-420
11. Camidge DR, Kono SA, Flacco A, et al. Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment. Clin Cancer Res. 2010 ; 16: 5581-5590
12. Yamamoto H, Kohashi K, Oda Y, et al. Absence of human herpesvirus-8 and Epstein-Barr virus in inflammatory myofibroblastic tumor with anaplastic large cell lymphoma kinase fusion gene. Pathol Int. 2006 ; 56: 584-590
13. Singhal M, Ramanathan S, Das A, Singh G, Bagga R, Khandelwal N. Omental inflammatory myofibroblastic tumour mimicking peritoneal carcinomatosis. Cancer Imaging. 2011 ; 11: 19-22
14. Kye BH, Kim HJ, Kang SG, Yoo C, Cho HM. A case of inflammatory myofibroblastic tumor originated from the greater omentum in young adult. J Korean Surg Soc. 2012 ; 82: 380-384
15. Griffin CA, Hawkins AL, Dvorak C, Henkle C, Ellingham T, Perlman EJ. Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. Cancer Res. 1999 ; 59: 2776-2780
16. Cole B, Zhou H, McAllister N, Afify Z, Coffin CM. Inflammatory myofibroblastic tumor with thrombocytosis and a unique chromosomal translocation with ALK rearrangement. Arch Pathol Lab Med. 2006 ; 130: 1042-1045
17. Shi H, Wei L, Sun L, Guo A. Primary gastric inflammatory myofibroblastic tumor: a clinicopathologic and immunohistochemical study of 5 cases. Pathol Res Pract. 2010 ; 206: 287-291
18. Bjelovic M, Micev M, Spica B, et al. Primary inflammatory myofibroblastic tumor of the stomach in an adult woman: a case report and review of the literature. World J Surg Oncol. 2013 ; 11: 35
19. Arslan D, Gunduz S, Tural D, et al. Inflammatory myofibroblastic tumor: a rarely seen submucosal lesion of the stomach. Case Rep Oncol Med. 2013 ; 2013: 328108
20. Milne AN, Sweeney KJ, O'Riordain DS, et al. Inflammatory myofibroblastic tumor with ALK/TPM3 fusion presenting as ileocolic intussusception: an unusual presentation of an unusual neoplasm. Hum Pathol. 2006 ; 37: 112-116
21. Zhou X, Luo C, Lv S, Gan M. Inflammatory myofibroblastic tumor of the rectum in a 13-month-old girl: a case report. J Pediatr Surg. 2011 ; 46 (7). E1 - E4
22. Paik JH, Choi CM, Kim H, et al. Clinicopathologic implication of ALK rearrangement in surgically resected lung cancer: a proposal of diagnostic algorithm for ALK-rearranged adenocarcinoma. Lung Cancer. 2012 ; 76: 403-409
23. Thunnissen E, Bubendorf L, Dietel M, et al. EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations. Virchows Arch. 2012 ; 461: 245-257
24. Butrynski JE, D'Adamo DR, Hornick JL, et al. Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor. N Engl J Med. 2010 ; 363: 1727-1733