CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo

Blood

Volumn 124, Issue 15, 2014, Pages 2431-2441

  Alshahrani, Musaed M ^a   Yang, Eunice ^a   Yip, Jana ^a   Ghanem, Simona S ^b   Abdallah, Simon L ^b   De Angelis, Anthony M ^b   O'Malley, Cindy J ^a   Moheimani, Fatemeh ^a   Najjar, Sonia M ^b   Jackson, Denise E ^a  

^a RMIT UNIVERSITY   (Australia)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TYPE LECTIN LIKE RECEPTOR 2; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 2; CELL SURFACE PROTEIN; COLLAGEN; COLLAGEN RELATED PEPTIDE; FC RECEPTOR; FERRIC CHLORIDE; FIBRILLAR COLLAGEN; GLYCOPROTEIN VI; LECTIN RECEPTOR; LIGAND; PEPTIDE; PROTEIN KINASE SYK; UNCLASSIFIED DRUG; CARRIER PROTEIN; CD66 ANTIGENS; CELL ADHESION MOLECULE; CLEC-2 PROTEIN, MOUSE; COLLAGEN TYPE 1; COLLAGEN-RELATED PEPTIDE; FIBRINOGEN RECEPTOR; LECTIN; LEUKOCYTE ANTIGEN; PHOSPHOLIPASE C GAMMA; PLATELET MEMBRANE GLYCOPROTEIN VI; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLE; ARTERY BLOOD FLOW; ARTICLE; BLOOD CLOTTING; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; CREMASTER MUSCLE; FEMALE; HEMATOPOIESIS; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; IN VITRO STUDY; IN VIVO STUDY; MALE; MESENTERY; MICROSCOPY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STIMULATION; THROMBOCYTE; THROMBUS; WILD TYPE; ANIMAL; BLOOD FLOW; C57BL MOUSE; CELL GRANULE; CELL MEMBRANE; DEFICIENCY; DRUG EFFECTS; INTRACELLULAR SPACE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; THROMBOSIS;

ANIMALS; ANTIGENS, CD; BLOOD PLATELETS; CARRIER PROTEINS; CELL ADHESION; CELL ADHESION MOLECULES; CELL MEMBRANE; COLLAGEN TYPE I; CYTOPLASMIC GRANULES; HEMATOPOIESIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SPACE; LECTINS, C-TYPE; MICE, INBRED C57BL; PEPTIDES; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN-TYROSINE KINASES; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; THROMBOSIS;

EID: 84907612583     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-04-569707     Document Type: Article

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