Neurodevelopmental disorders and prenatal residential proximity to agricultural pesticides: The charge study

Environmental Health Perspectives

Volumn 122, Issue 10, 2014, Pages 1103-1109

  Shelton, Janie F ^a   Geraghty, Estella M ^b   Tancredi, Daniel J ^a   Delwiche, Lora D ^a   Schmidt, Rebecca J ^a   Ritz, Beate ^c,d   Hansen, Robin L ^a,e   Hertz Picciotto, Irva ^a,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEPHATE; CARBAMIC ACID; CHLORPYRIFOS; CYHALOTHRIN; CYPERMETHRIN; DIMPYLATE; FENVALERATE; PERMETHRIN; PESTICIDE; PYRETHROID; TAU FLUVALINATE; UNCLASSIFIED DRUG; CARBAMIC ACID DERIVATIVE; CHLORINATED HYDROCARBON; ORGANOPHOSPHATE;

ARTICLE; AUTISM; BRAIN DEVELOPMENT; CASE CONTROL STUDY; CHILD; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DISEASE ASSOCIATION; ENVIRONMENTAL EXPOSURE; FEMALE; GESTATION PERIOD; HUMAN; MAJOR CLINICAL STUDY; MALE; POPULATION EXPOSURE; POPULATION RESEARCH; PREGNANCY; PREGNANCY OUTCOME; PRENATAL EXPOSURE; PRESCHOOL CHILD; QUESTIONNAIRE; RESIDENTIAL AREA; ADULT; ADVERSE EFFECTS; CALIFORNIA; CHILD DEVELOPMENT DISORDERS, PERVASIVE; DEMOGRAPHY; DEVELOPMENTAL DISABILITIES; ODDS RATIO; STATISTICS AND NUMERICAL DATA;

ADULT; CALIFORNIA; CARBAMATES; CASE-CONTROL STUDIES; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CHILD, PRESCHOOL; DEVELOPMENTAL DISABILITIES; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; HYDROCARBONS, CHLORINATED; MALE; ODDS RATIO; ORGANOPHOSPHATES; PESTICIDES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PYRETHRINS; RESIDENCE CHARACTERISTICS;

EID: 84907611637     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1307044     Document Type: Article

References (51)

1. Agency for Toxic Substances and Disease Registry. 2003. Toxicological Profile for Pyrethrins and Pyrethroids. Available: http://www.atsdr.cdc.gov/toxprofiles/tp155.pdf [accessed 22 February 2014].
2. American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders-IV-TR. Washington, DC:American Psychiatric Association.
3. Bouchard MF, Bellinger DC, Wright RO, Weisskopf MG. 2010. Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides. Pediatrics 125(6):e1270–e1277.
4. Bouchard MF, Chevrier J, Harley KG, Kogut K, Vedar M, Calderon N, et al. 2011. Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. Environ Health Perspect 119:1189–1195; doi:10.1289/ehp.1003185.
5. Boyle CA, Boulet S, Schieve LA, Cohen RA, Blumberg SJ, Yeargin-Allsopp M, et al. 2011. Trends in the prevalence of developmental disabilities in US children, 1997–2008. Pediatrics 127(6):1034–1042.
6. Breckenridge CB, Holden L, Sturgess N, Weiner M, Sheets L, Sargent D, et al. 2009. Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticides. Neurotoxicology 30(suppl 1):S17–S31.
7. California Department of Food and Agriculture. 2010. California Agricultural Production Statistics. Available: http://www.cdfa.ca.gov/statistics/ [accessed 12 February 2012].
8. Casida JE. 2009. Pest toxicology: the primary mechanisms of pesticide action. Chem Res Toxicol 22(4):609–619.
9. CDPR (California Department of Pesticide Regulation). 2014. Pesticide Use Reporting (PUR). Available: http://www.cdpr.ca.gov/docs/pur/purmain.htm [accessed 22 May 2014].
10. Centers for Disease Control and Prevention. 2012. Prevalence of Autism Spectrum Disorders—Autism and Developmental Disabilities Monitoring Network, 14 Sites, United States, 2008. Available: http://www.cdc.gov/mmwr/preview/mmwrhtml/ss6103a1.htm [accessed 27 May 2014].
11. Costa LG, Cole TB, Vitalone A, Furlong CE. 2005. Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clin Chim Acta 352(1–2):37–47.
12. Croen LA, Grether JK, Hoogstrate J, Selvin S. 2002. The changing prevalence of autism in California. J Autism Dev Disord 32(3):207–215.
13. D’Amelio M, Ricci I, Sacco R, Liu X, D’Agruma L, Muscarella LA, et al. 2005. Paraoxonase gene variants are associated with autism in North America, but not in Italy: possible regional specificity in gene–environment interactions. Mol Psychiatry 10(11):1006–1016.
14. Engel SM, Berkowitz GS, Barr DB, Teitelbaum SL, Siskind J, Meisel SJ, et al. 2007. Prenatal organophosphate metabolite and organochlorine levels and performance on the Brazelton Neonatal Behavioral Assessment Scale in a multiethnic pregnancy cohort. Am J Epidemiol 165(12):1397–1404.
15. Eskenazi B, Marks AR, Bradman A, Fenster L, Johnson C, Barr DB, et al. 2006. In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American children. Pediatrics 118(1):233–241.
16. Eskenazi B, Marks AR, Bradman A, Harley K, Barr DB, Johnson C, et al. 2007. Organophosphate pesticide exposure and neurodevelopment in young Mexican- American children. Environ Health Perspect 115:792–798; doi:10.1289/ehp.9828.
17. Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, et al. 2005. Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. Neurotoxicology 26(4):651–659.
18. Grandjean P, Harari R, Barr DB, Debes F. 2006. Pesticide exposure and stunting as independent predictors of neurobehavioral deficits in Ecuadorian school children. Pediatrics 117(3):e546–e556.
19. Guillette EA, Meza MM, Aquilar MG, Soto AD, Garcia IE. 1998. An anthropological approach to the evaluation of preschool children exposed to pesticides in Mexico. Environ Health Perspect 106:347–353.
20. Gunier RB, Ward MH, Airola M, Bell EM, Colt J, Nishioka M, et al. 2011. Determinants of agricultural pesticide concentrations in carpet dust. Environ Health Perspect 119:970–976; doi:10.1289/ehp.1002532.
21. Hallmayer J, Cleveland S, Torres A, Phillips J, Cohen B, Torigoe T, et al. 2011. Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry 68(11):1095–1102.
22. Handal AJ, Harlow SD, Breilh J, Lozoff B. 2008. Occupational exposure to pesticides during pregnancy and neurobehavioral development of infants and toddlers. Epidemiology 19(6):851–859.
23. Hertz-Picciotto I, Croen LA, Hansen R, Jones CR, van de Water J, Pessah IN. 2006. The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environ Health Perspect 114:1119–1125; doi:10.1289/ehp.8483.
24. Lassiter TL, MacKillop EA, Ryde IT, Seidler FJ, Slotkin TA. 2009. Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells. Brain Res Bull 78(6):313–322.
25. Le Couteur A, Lord C, Rutter M. 2003. Autism Diagnostic Interview–Revised (ADI-R). Los Angeles:Western Psychological Services.
26. Lee PC, Rhodes SL, Sinsheimer JS, Bronstein J, Ritz B. 2013. Functional paraoxonase 1 variants modify the risk of Parkinson’s disease due to organophosphate exposure. Environ Int 56:42–47.
27. Levin ED, Addy N, Nakajima A, Christopher NC, Seidler FJ, Slotkin TA. 2001. Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats. Brain Res Dev Brain Res 130(1):83–89.
28. Levin ED, Timofeeva OA, Yang L, Petro A, Ryde IT, Wrench N, et al. 2010. Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging. Behav Brain Res 208(2):319–327.
29. Lord C, Pickles A, McLennan J, Rutter M, Bregman J, Folstein S, et al. 1997. Diagnosing autism: analyses of data from the Autism Diagnostic Interview. J Autism Dev Disord 27(5):501–517.
30. Lord C, Rutter M, DiLavore PC, Risi S. 2000. The Autism Diagnostic Observation Schedule (ADOS). Los Angeles:Western Psychological Services.
31. Lord C, Rutter M, DiLavore PC, Risi S. 2003. Autism Diagnostic Observation Schedule Manual. Los Angeles:Western Psychological Services.
32. Lord C, Rutter M, Le Couteur A. 1994. Autism Diagnostic Interview–Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 24(5):659–685.
33. Mendola P, Selevan SG, Gutter S, Rice D. 2002. Environmental factors associated with a spectrum of neurodevelopmental deficits. Ment Retard Dev Disabil Res Rev 8(3):188–197.
34. Mense SM, Sengupta A, Lan C, Zhou M, Bentsman G, Volsky DJ, et al. 2006. The common insecticides cyfluthrin and chlorpyrifos alter the expression of a subset of genes with diverse functions in primary human astrocytes. Toxicol Sci 93(1):125–135.
35. Morgan MK. 2012. Children’s exposures to pyrethroid insecticides at home: a review of data collected in published exposure measurement studies conducted in the United States. Int J Environ Res Public Health 9(8):2964–2985.
36. Mullen EM. 1995. Mullen Scales of Early Learning. Circle Pines, MN:American Guidance Services Inc.
37. Nuckols JR, Gunier RB, Riggs P, Miller R, Reynolds P, Ward MH. 2007. Linkage of the California Pesticide Use Reporting Database with spatial land use data for exposure assessment. Environ Health Perspect 115:684–689; doi:10.1289/ehp.9518.
38. Rauh VA, Garfinkel R, Perera FP, Andrews HF, Hoepner L, Barr DB, et al. 2006. Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first 3 years of life among inner-city children. Pediatrics 118(6):e1845–e1859.
39. Ribas-Fito N, Torrent M, Carrizo D, Munoz-Ortiz L, Julvez J, Grimalt JO, et al. 2006. In utero exposure to background concentrations of DDT and cognitive functioning among preschoolers. Am J Epidemiol 164(10):955–962.
40. Roberts EM, English PB, Grether JK, Windham GC, Somberg L, Wolff C. 2007. Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley. Environ Health Perspect 115:1482–1489; doi:10.1289/ehp.10168.
41. Rull RP, Ritz B. 2003. Historical pesticide exposure in California using pesticide use reports and land-use surveys: an assessment of misclassification error and bias. Environ Health Perspect 111:1582–1589; doi:10.1289/ehp.6118.
42. Rutter M, Bailey A, Berument SK, Lord C, Pickles A. 2003. Social Communication Questionnaire (SCQ). Los Angeles:Western Psychological Services.
43. Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tancredi DJ, et al. 2011. Prenatal vitamins, onecarbon metabolism gene variants, and risk for autism. Epidemiology 22(4):476–485.
44. Shelton JF, Hertz-Picciotto I, Pessah IN. 2012. Tipping the balance of autism risk: potential mechanisms linking pesticides and autism. Environ Health Perspect 120:944–951; doi:10.1289/ehp.1104553.
45. Sparrow S, Balla D, Cicchetti D. 2005. Vineland Adaptive Behavior Scales Interview Edition Expanded Form Manual. Circle Pines, MN:American Guidance Services Inc.
46. Torres-Sánchez L, Rothenberg SJ, Schnaas L, Cebrián ME, Osorio E, del Carmen Hernández M, et al. 2007. In utero p,p’-DDE exposure and infant neurodevelopment: a perinatal cohort in Mexico. Environ Health Perspect 115:435–439; doi:10.1289/ehp.9566.
47. U.S. Department of Agriculture. 2006. Pest Management Practices. Available: http://www.ers.usda.gov/ersDownloadHandler.ashx?file=/media/873656/pestmgt.pdf [accessed 2 June 2014].
48. U.S. Environmental Protection Agency. 2011. Pesticide Industry Sales and Usage: 2006 and 2007 Market Estimates. Available: http://www.epa.gov/opp00001/pestsales/07pestsales/market_estimates2007.pdf [accessed 27 May 2014].
49. Weng HY, Hsueh YH, Messam LL, Hertz-Picciotto I. 2009. Methods of covariate selection: directed acyclic graphs and the change-in-estimate procedure. Am J Epidemiol 169(10):1182–1190.
50. Williams MK, Rundle A, Holmes D, Reyes M, Hoepner LA, Barr DB, et al. 2008. Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000–2001 U.S. Environmental Protection Agency restriction of organophosphates. Environ Health Perspect 116:1681–1688; doi:10.1289/ehp.11367.
51. Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, et al. 2005. Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates. Neurotoxicology 26(2):199–209.