Reduction in incidence of hospitalizations for psychotic episodes through early identification and intervention

Psychiatric Services

Volumn 65, Issue 10, 2014, Pages 1194-1200

  McFarlane, William R ^a   Susser, Ezra ^b   McCleary, Richard ^c   Verdi, Mary ^a   Lynch, Sarah ^a   Williams, Deanna ^a   McKeague, Ian W ^b  

^a Maine Medical Center Research Institute   (United States)

^b Department of Medicine   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE PREDISPOSITION; EARLY DIAGNOSIS; EARLY INTERVENTION; FEMALE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH SERVICE; OUTCOME ASSESSMENT; PATIENT REFERRAL; PREVENTION STUDY; PREVENTIVE HEALTH SERVICE; PROGRAM EFFICACY; PSYCHOSIS; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; UNITED STATES; URBAN AREA; YOUNG ADULT; MAINE; PROCEDURES; PROGRAM EVALUATION; PSYCHOTIC DISORDERS; STATISTICS AND NUMERICAL DATA;

ADOLESCENT; ADULT; CHILD; COMMUNITY MENTAL HEALTH SERVICES; FEMALE; HOSPITALIZATION; HUMANS; INCIDENCE; MAINE; MALE; OUTCOME ASSESSMENT (HEALTH CARE); PROGRAM EVALUATION; PSYCHOTIC DISORDERS; YOUNG ADULT;

EID: 84907611180     PISSN: 10752730     EISSN: 15579700     Source Type: Journal    
DOI: 10.1176/appi.ps.201300336     Document Type: Article

References (35)

1. Murray CJL, Vos T, Lozano R, et al: Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380:2197-2223, 2012
2. Wu EQ, Birnbaum HG, Shi L, et al: The economic burden of schizophrenia in the United States in 2002. Journal of Clinical Psychiatry 66:1122-1129, 2005
3. Lehman AF, Steinwachs DM: Translating research into practice: the Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations. Schizophrenia Bulletin 24:1-10, 1998
4. Fusar-Poli P, Bonoldi I, Yung AR, et al: Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk. Archives of General Psychiatry 69:220-229, 2012
5. Fusar-Poli P, Meneghelli A, Valmaggia L, et al: Duration of untreated prodromal symptoms and 12-month functional outcome of individuals at risk of psychosis. British Journal of Psychiatry 194:181-182, 2009
6. O'Connell ME, Boat T, Warner KE (eds): Preventing Mental, Emotional and Behavioral Disorders Among Young People. Washington, DC, National Academies Press, 2009
7. Ruhrmann S, Schultze-Lutter F, Salokangas RK, et al: Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European prediction of psychosis study. Archives of General Psychiatry 67:241-251, 2010
8. McGlashan TH, Zipursky RB, Perkins D, et al: Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. American Journal of Psychiatry 163:790-799, 2006
9. Morrison AP, French P, Walford L, et al: Cognitive therapy for the prevention of psychosis in people at ultra-high risk: randomised controlled trial. British Journal of Psychiatry 185:291-297, 2004
10. Nordentoft M, Thorup A, Petersen L, et al: Transition rates from schizotypal disorder to psychotic disorder for first-contact patients included in the OPUS trial: a randomized clinical trial of integrated treatment and standard treatment. Schizophrenia Research 83:29-40, 2006
11. Amminger GP, Schäfer MR, Papageorgiou K, et al: Long-chain omega-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial. Archives of General Psychiatry 67:146-154, 2010
12. Bechdolf A, Wagner M, Ruhrmann S, et al: Preventing progression to first-episode psychosis in early initial prodromal states. British Journal of Psychiatry 200:22-29, 2012
13. van der Gaag M, Nieman DH, Rietdijk J, et al: Cognitive behavioral therapy for subjects at ultrahigh risk for developing psychosis: a randomized controlled clinical trial. Schizophrenia Bulletin 38:1180-1188, 2012
14. McGorry PD, Yung AR, Phillips LJ, et al: Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Archives of General Psychiatry 59:921-928, 2002
15. Addington J, Epstein I, Liu L, et al: A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis. Schizophrenia Research 125:54-61, 2011
16. McGorry PD, Nelson B, Phillips LJ, et al: Randomized controlled trial of interventions for young people at ultra-high risk of psychosis: twelve-month outcome. Journal of Clinical Psychiatry 74:349-356, 2013
17. Fusar-Poli P, Borgwardt SJ, Bechdolf A, et al: The psychosis high-risk state: a comprehensive state-of-the-art review. JAMA Psychiatry 70:107-120, 2013
18. Francey SMNB, Nelson B, Thompson A, et al: Who needs antipsychotic medication in the earliest stages of psychosis? A reconsideration of benefits, risks, neurobiology and ethics in the era of early intervention. Schizophrenia Research 119:1-10, 2010
19. Falloon IR: Early intervention for first episodes of schizophrenia: a preliminary exploration. Psychiatry 55:4-15, 1992
20. McFarlane WR, Cook WL, Downing D, et al: Portland identification and early referral: a community-based system for identifying and treating youths at high risk of psychosis. Psychiatric Services 61:512-515, 2010
21. Kirkbride JB, Fearon P, Morgan C, et al: Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study. Archives of General Psychiatry 63:250-258, 2006
22. Joly BM, Pukstas BK, Elbaum WM, et al: Promoting early detection of psychosis: the role of community outreach. Journal of Public Mental Health 11:195-208, 2012
23. McGlashan TH, Miller, T, Woods, S, et al: Structured Interview for Prodromal Syndromes. New Haven, Conn, Yale School of Medicine, 2003
24. McFarlane WR: Family-based treatment in prodromal and first-episode psychosis; in Early Intervention in Psychotic Disorders. Edited by Miller T. Amsterdam, Kluwer Academic, 2001
25. McCleary R, McDowall D: Time series designs; in Handbook of Research Methods in Psychology. Edited by Cooper H. Washington, DC, American Psychological Association, 2012
26. Box GEP, Tiao GC: Intervention analysis with applications to economic and environmental problems. Journal of the American Statistical Association 349:70-79, 1975
27. Liu L-M, Hudak GB, Box GEP, et al: Forecasting and Time Series Analysis Using the SCA Statistical System.Chicago, Scientific Computing Associates Corp, 1997
28. McGlashan TH: Early detection and intervention in schizophrenia: research. Schizophrenia Bulletin 22:327-345, 1996
29. Salokangas RKR, Helminen M, Koivisto A-M, et al: Incidence of hospitalised schizophrenia in Finland since 1980: decreasing and increasing again. Social Psychiatry and Psychiatric Epidemiology 46:343-350, 2011
30. Thorup A, Waltoft BL, Pedersen CB, et al: Young males have a higher risk of developing schizophrenia: a Danish register study. Psychological Medicine 37:479-484, 2007
31. Cannon TD, Cadenhead K, Cornblatt B, et al: Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Archives of General Psychiatry 65:28-37, 2008
32. Cornblatt B, Lencz T, Obuchowski M: The schizophrenia prodrome: treatment and high-risk perspectives. Schizophrenia Research 54:177-186, 2002
33. McFarlane WR, Cook WL, Downing D, et al: Early Detection, Intervention and Prevention of Psychosis Program: rationale, design, and sample description. Adolescent Psychiatry 2:112-124, 2012
34. Nelson B, Yuen HP, Wood SJ, et al: Long-term follow-up of a group at ultra high risk ("prodromal") for psychosis: the PACE 400 study. JAMA Psychiatry 70:793-802, 2013
35. Klosterkötter J, Hellmich M, Steinmeyer EM, et al: Diagnosing schizophrenia in the initial prodromal phase. Archives of General Psychiatry 58:158-164, 2001