The effects of low-intensity pulsed ultrasound and pulsed electromagnetic fields bone growth stimulation in acute fractures: A systematic review and meta-analysis of randomized controlled trials

Archives of Orthopaedic and Trauma Surgery

Volumn 134, Issue 8, 2014, Pages 1093-1106

  Hannemann, P F W ^a   Mommers, E H H ^a   Schots, J P M ^a   Brink, P R G ^a   Poeze, M ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Fractures; Healing; Low intensity pulsed ultrasound; Nonunion; Pulsed electromagnetic fields

Indexed keywords

PLACEBO;

ARM FRACTURE; ARTICLE; BONE GROWTH; DIAPHYSIS; EVIDENCE BASED MEDICINE; FRACTURE; FRACTURE HEALING; FRACTURE NONUNION; GROWTH STIMULATION; HUMAN; LOW INTENSITY PULSED ULTRASOUND THERAPY; META ANALYSIS; METAPHYSIS; OUTCOME ASSESSMENT; PHYSICAL MEDICINE; PULSED ELECTROMAGNETIC FIELD THERAPY; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYSTEMATIC REVIEW; THERAPY EFFECT; ADULT; COMPARATIVE STUDY; ELECTROMAGNETIC FIELD; ELECTROSTIMULATION THERAPY; MAGNETOTHERAPY; METHODOLOGY; PHYSIOLOGY; REVIEW; TREATMENT OUTCOME; ULTRASOUND THERAPY;

ADULT; ELECTRIC STIMULATION THERAPY; ELECTROMAGNETIC FIELDS; FRACTURE HEALING; FRACTURES, BONE; HUMANS; MAGNETIC FIELD THERAPY; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME; ULTRASONIC THERAPY;

EID: 84907609949     PISSN: 09368051     EISSN: 14343916     Source Type: Journal    
DOI: 10.1007/s00402-014-2014-8     Document Type: Article

References (33)

1. van der Molen AB, Groothoff JW, Visser GJ, Robinson PH, Eisma WH (1999) Time off work due to scaphoid fractures and other carpal injuries in The Netherlands in the period 1990 to 1993 J Hand Surg 24(2):193-198
2. Bonafede M, Espindle D, Bower AG (2013) The direct and indirect costs of long bone fractures in a working age US population. J Med Econ 16(1):169-178
3. Griffin XL, Costello I, Costa ML (2008) The role of low intensity pulsed ultrasound therapy in the management of acute fractures: a systematic review. J Trauma 65(6):1446-1452
4. Walker NA, Denegar CR, Preische J (2007) Low-intensity pulsed ultrasound and pulsed electromagnetic field in the treatment of tibial fractures: a systematic review. J Athl Train 42(4):530-535
5. Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:b2535
6. Higgins J, Altman DG (2008) Assessing risk of bias in included studies. In: Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series. Wiley, pp 187-241
7. Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159-174
8. Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21(11):1539-1558
9. Heckman JD, Ryaby JP, McCabe J, Frey JJ, Kilcoyne RF (1994) Acceleration of tibial fracture-healing by non-invasive, low-intensity pulsed ultrasound. J Bone Joint Surg Am Vol 76(1):26-34
10. Kristiansen TK, Ryaby JP, McCabe J, Frey JJ, Roe LR (1997) Accelerated healing of distal radial fractures with the use of specific, low-intensity ultrasound. A multicenter, prospective, randomized, double-blind, placebo-controlled study. J Bone Joint Surg Am Vol 79(7):961-973
11. Emami A, Petren-Mallmin M, Larsson S (1999) No effect of lowintensity ultrasound on healing time of intramedullary fixed tibial fractures. J Orthop Trauma 13(4):252-257
12. Mayr E, Rudzki MM, Rudzki M, Borchardt B, Hausser H, Ruter A (2000) Does low intensity, pulsed ultrasound speed healing of scaphoid fractures? Handchir Mikrochir Plast Chir 32(2):115-122
13. Leung KS, Lee WS, Tsui HF, Liu PP, Cheung WH (2004) Complex tibial fracture outcomes following treatment with low-intensity pulsed ultrasound. Ultrasound Med Biol 30(3):389-395
14. Handolin L, Kiljunen V, Arnala I, Kiuru MJ, Pajarinen J, Partio EK et al (2005) No long-term effects of ultrasound therapy on bioabsorbable screw-fixed lateral malleolar fracture. Scand J Surg 94(3):239-242
15. Handolin L, Kiljunen V, Arnala I, Kiuru MJ, Pajarinen J, Partio EK et al (2005) Effect of ultrasound therapy on bone healing of lateral malleolar fractures of the ankle joint fixed with bioabsorbable screws. J Orthop Sci 10(4):391-395
16. Handolin L, Kiljunen V, Arnala I, Pajarinen J, Partio EK, Rokkanen P (2005) The effect of low intensity ultrasound and bioabsorbable self-reinforced poly-l-lactide screw fixation on bone in lateral malleolar fractures. Arch Orthop Trauma Surg 125(5):317-321
17. Lubbert PH, van der Rijt RH, Hoorntje LE, van der Werken C (2008) Low-intensity pulsed ultrasound (LIPUS) in fresh clavicle fractures: a multi-centre double blind randomised controlled trial. Injury 39(12):1444-1452
18. Rue JP, Armstrong DW 3rd, Frassica FJ, Deafenbaugh M, Wilckens JH (2004) The effect of pulsed ultrasound in the treatment of tibial stress fractures. Orthopedics 27(11):1192-1195
19. Faldini C, Cadossi M, Deianira L, Betti E, Chiarello E, Giannini S (2010) Electromagnetic bone growth stimulation in patients with femoral neck fractures treated with screws: prospective randomized double-blind study. Curr Orthop Pract 21(3):282-287
20. Adie S, Harris IA, Naylor JM, Rae H, Dao A, Yong S et al (2011) Pulsed electromagnetic field stimulation for acute tibial shaft fractures: a multicenter, double-blind, randomized trial. J Bone Joint Surg Am Vol 93(17):1569-1576
21. Hannemann PF, Gottgens KW, van Wely BJ, Kolkman KA, Werre AJ, Poeze M et al (2012) The clinical and radiological outcome of pulsed electromagnetic field treatment for acute scaphoid fractures: a randomised double-blind placebo-controlled multicentre trial. J Bone Joint Surg Br Vol 94(10):1403-1408
22. Ardan NI Jr, Janes JM, Herrick JF (1954) Changes in bone after exposure to ultrasonic energy. Minn Med 37(6):415-420
23. Borsalino G, Bagnacani M, Bettati E, Fornaciari F, Rocchi R, Uluhogian S et al (1988) Electrical stimulation of human femoral intertrochanteric osteotomies. Double-blind study. Clin Orthop Relat Res 237:256-263
24. Azuma Y, Ito M, Harada Y, Takagi H, Ohta T, Jingushi S (2001) Low-intensity pulsed ultrasound accelerates rat femoral fracture healing by acting on the various cellular reactions in the fracture callus. J Bone Miner Res 16(4):671-680
25. Sharrard WJ (1990) A double-blind trial of pulsed electromagnetic fields for delayed union of tibial fractures. J Bone Joint Surg Br Vol 72(3):347-355
26. Bassett CA, Mitchell SN, Gaston SR (1981) Treatment of ununited tibial diaphyseal fractures with pulsing electromagnetic fields. J Bone Joint Surg Br Vol 63(4):511-523
27. Nolte PA, van der Krans A, Patka P, Janssen IM, Ryaby JP, Albers GH (2001) Low-intensity pulsed ultrasound in the treatment of nonunions. J Trauma 51(4):693-702 discussion-3
28. Schofer MD, Block JE, Aigner J, Schmelz A (2010) Improved healing response in delayed unions of the tibia with low-intensity pulsed ultrasound: results of a randomized sham-controlled trial. BMC Musculoskelet Disord 11:229
29. Bashardoust Tajali S, Houghton P, MacDermid JC, Grewal R (2012) Effects of low-intensity pulsed ultrasound therapy on fracture healing: a systematic review and meta-analysis. Am J Phys Med Rehabilitation Assoc Acad Physiatr 91(4):349-367
30. Poolman RW, Abouali JA, Conter HJ, Bhandari M (2007) Overlapping systematic reviews of anterior cruciate ligament reconstruction comparing hamstring autograft with bone-patellar tendon-bone autograft: why are they different? J Bone Joint Surg Am Vol 89(7):1542-1552
31. Bhandari M, Fong K, Sprague S, Williams D, Petrisor B (2012) Variability in the definition and perceived causes of delayed unions and nonunions: a cross-sectional, multinational survey of orthopaedic surgeons. J Bone Joint Surg Am Vol 94(15):e1091-e1096
32. Corrales LA, Morshed S, Bhandari M, Miclau T 3rd (2008) Variability in the assessment of fracture-healing in orthopaedic trauma studies. J Bone Joint Surg Am Vol 90(9):1862-1868
33. Button ML, Sprague S, Gharsaa O, Latouche S, Bhandari M (2009) Economic evaluation of bone stimulation modalities: a systematic review of the literature. Indian J Orthop 43(2):168-174