Association study of susceptibility loci with specific breast cancer subtypes in Chinese women

Breast Cancer Research and Treatment

Volumn 146, Issue 3, 2014, Pages 503-514

  Zhang, Bo ^a   Li, Yang ^a,b   Li, Longnian ^a,b   Chen, Mengyun ^a   Zhang, Cuicui ^a   Zuo, Xian Bo ^a,b   Zhou, Fu Sheng ^a,b   Liang, Bo ^a,b   Zhu, Jun ^a,b   Li, Pan ^a,b   Huang, Zhong Lian ^a   Xuan, Han ^a   Li, Wei ^a   Chen, Zhen Dong ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Ministry of National Science and Technology   (China)

Author keywords

Association studies; Breast cancer; Chinese women; Single nucleotide polymorphisms (SNPs); Subtypes

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GESTAGEN; ERBB2 PROTEIN, HUMAN; TUMOR PROTEIN;

ADULT; ARTICLE; BREAST CANCER; CANCER CLASSIFICATION; CANCER SUSCEPTIBILITY; CHINESE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; POPULATION RESEARCH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WOMEN'S HEALTH; ASIAN CONTINENTAL ANCESTRY GROUP; BIOSYNTHESIS; BREAST TUMOR; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; PATHOLOGY; RISK FACTOR;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BREAST NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MIDDLE AGED; NEOPLASM PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, ERBB-2; RISK FACTORS;

EID: 84907598501     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-3041-4     Document Type: Article

References (31)

1. Key TJ, Verkasalo PK, Banks E (2001) Epidemiology of breast cancer. Lancet Oncol 2(3):133-140 (Pubitemid 33585924)
2. Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447(7148):1087-1093 (Pubitemid 47014426)
3. Zhang B, Li Y, Zheng X, Zuo X, Zhou F, Liang B, Zhu J, Li P, Ding Y, Huang Z (2013) A common variant in the SIAH2 locus is associated with estrogen receptor-positive breast cancer in the chinese han population. PLoS One 8(11):e79365
4. D B, MR V, C H, Y L, B Z, E S, WD D, XJ Z, F W (2013) Comparison of genetic variation of breast cancer susceptibility genes in Chinese and German populations. Eur J Hum Genet 13(10):38
5. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK (2013) Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 45(4):353-361
6. Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS (2013) Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 45(4):392-398
7. Goldhirsch A, Wood W, Coates A, Gelber R, Thürlimann B, Senn H-J (2011) Strategies for subtypes-dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. Ann Oncol 22(8):1736-1747
8. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, De Bakker PI, Daly MJ (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81(3):559-575 (Pubitemid 47330214)
9. Keyse SM (2008) Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 27(2):253-261
10. Gröschl B, Bettstetter M, Giedl C, Woenckhaus M, Edmonston T, Hofstädter F, Dietmaier W (2013) Expression of the MAP kinase phosphatase DUSP4 is associated with microsatellite instability in colorectal cancer (CRC) and causes increased cell proliferation. Int J Cancer 132(7):1537-1546
11. Teutschbein J, Haydn JM, Samans B, Krause M, Eilers M, Schartl M, Meierjohann S (2010) Gene expression analysis after receptor tyrosine kinase activation reveals new potential melanoma proteins. BMC Cancer 10(1):386
12. Sieben NL, Oosting J, Flanagan AM, Prat J, Roemen GM, Kolkman-Uljee SM, van Eijk R, Cornelisse CJ, Fleuren GJ, van Engeland M (2005) Differential gene expression in ovarian tumors reveals Dusp 4 and Serpina 5 as key regulators for benign behavior of serous borderline tumors. J Clin Oncol 23(29):7257-7264 (Pubitemid 46202340)
13. H-y Wang, Cheng Z, Malbon CC (2003) Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer. Cancer Lett 191(2):229-237 (Pubitemid 36255609)
14. Mochizuki S, Okada Y (2007) ADAMs in cancer cell proliferation and progression. Cancer Sci 98(5):621-628 (Pubitemid 46563436)
15. Shiomi T, Okada Y(2003) MT1-MMP and MMP-7 in invasion and metastasis of human cancers. Cancer Metastasis Rev 22(2-3):145-152 (Pubitemid 36561054)
16. Fq Wang, So J, Reierstad S, Fishman DA (2005) Matrilysin (MMP-7) promotes invasion of ovarian cancer cells by activation of progelatinase. Int J Cancer 114(1):19-31
17. Wei X, Moncada-Pazos A, Cal S, Soria-Valles C, Gartner J, Rudloff U, Lin JC, Rosenberg SA, López-Otín C, Samuels Y (2011) Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma. Hum Mutat 32(6):E2148-E2175
18. Eriksson N, Benton GM, Do CB, Kiefer AK, Mountain JL, Hinds DA, Francke U, Tung JY (2012) Genetic variants associated with breast size also influence breast cancer risk. BMC Med Genet 13(1):53
19. Ikram MS, Neill GW, Regl G, Eichberger T, Frischauf A-M, Aberger F, Quinn A, Philpott M (2004) GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter. J Investig Dermatol 122(6):1503-1509 (Pubitemid 38757234)
20. Kubo M, Nakamura M, Tasaki A, Yamanaka N, Nakashima H, Nomura M, Kuroki S, Katano M (2004) Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer. Cancer Res 64(17):6071-6074 (Pubitemid 39129406)
21. Jin G, Wang L, Chen W, Hu Z, Zhou Y, Tan Y, Wang J, Hua Z, Ding W, Shen J (2007) Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population. Int J Cancer 120(6):1330-1335
22. Biswas S, Trobridge P, Romero-Gallo J, Billheimer D, Myeroff LL, Willson JK, Markowitz SD, Grady WM (2008) Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor b resistant cells. Genes Chromosom Cancer 47(2):95-106
23. Volinia S, Calin GA, Liu C-G, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103(7):2257-2261 (Pubitemid 43271657)
24. Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA (2011) Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Investig 121(7):2750
25. Kaklamani V, Yi N, Sadim M, Siziopikou K, Zhang K, Xu Y, Tofilon S, Agarwal S, Pasche B, Mantzoros C (2011) The role of the fat mass and obesity associated gene (FTO) in breast cancer risk. BMC Med Genet 12(1):52
26. Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA (2000) Molecular portraits of human breast tumours. Nature 406(6797):747-752
27. Cheang MC, Chia SK, Voduc D, Gao D, Leung S, Snider J, Watson M, Davies S, Bernard PS, Parker JS (2009) Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst 101(10):736-750
28. Cornen S, Guille A, Adélaïde J, Addou-Klouche L, Finetti P, Saade M-R, Manai M, Carbuccia N, Bekhouche I, Letessier A (2014) Candidate luminal B breast cancer genes identified by genome, gene expression and dna methylation profiling. PLoS One 9(1):e81843
29. Network CGA (2012) Comprehensive molecular portraits of human breast tumours. Nature 490(7418):61-70
30. Norum J, Andersen K, Sørlie T (2014) Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy. Br J Surg 100:589-598
31. Goldhirsch A, Winer E, Coates A, Gelber R, Piccart-Gebhart M, Thürlimann B, Senn H-J, Albain KS, André F, Bergh J (2013) Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013. Ann Oncol 24(9):2206-2223