Inhibition of the central melanocortin system decreases brown adipose tissue activity

Journal of Lipid Research

Volumn 55, Issue 10, 2014, Pages 2022-2032

  Kooijman, Sander ^a   Boon, Mariëtte R ^a   Parlevliet, Edwin T ^a,b   Geerling, Janine J ^a   Van De Pol, Vera ^a   Romijn, Johannes A ^b   Havekes, Louis M ^a,c   Meurs, Illiana ^a   Rensen, Patrick C N ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c TNO   (Netherlands)

Author keywords

Energy expenditure; Liver; Triglycerides; Very low density lipoprotein; White adipose tissue

Indexed keywords

APOLIPOPROTEIN E; FAT DROPLET; MELANOCORTIN; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; TRIACYLGLYCEROL; UNCOUPLING PROTEIN 1; VERY LOW DENSITY LIPOPROTEIN; APOLIPOPROTEIN E3; INTERMEDIN; MC3R PROTEIN, MOUSE; MC4R PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY FAT; BROWN ADIPOSE TISSUE; CENTRAL MELANOCORTIN SYSTEM; CONTROLLED STUDY; DYSLIPIDEMIA; ENDOCRINE SYSTEM; ENERGY EXPENDITURE; FAT MASS; FATTY LIVER; FEMALE; FOOD INTAKE; HORMONE INHIBITION; LIPID ANALYSIS; LIPID OXIDATION; LIPID STORAGE; MOUSE; NONHUMAN; OBESITY; SIGNAL TRANSDUCTION; WEIGHT GAIN; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; TRANSGENIC MOUSE;

ADIPOSE TISSUE, BROWN; ANIMALS; APOLIPOPROTEIN E3; FEMALE; MELANOCYTE-STIMULATING HORMONES; MICE; MICE, TRANSGENIC; OXIDATION-REDUCTION; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTOR, MELANOCORTIN, TYPE 4; SIGNAL TRANSDUCTION;

EID: 84907535675     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M045989     Document Type: Article

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