Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease

British Journal of Haematology

Volumn 167, Issue 2, 2014, Pages 214-223

  Lin, Thet Thet ^a   Norris, Kevin ^a   Heppel, Nicole H ^a   Pratt, Guy ^b,c   Allan, James M ^d   Allsup, David J ^e   Bailey, James ^e   Cawkwell, Lynn ^e   Hills, Robert ^a   Grimstead, Julia W ^a   Jones, Rhiannon E ^a   Britt Compton, Bethan ^a   Fegan, Chris ^a   Baird, Duncan M ^a   Pepper, Chris ^a  

^a CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^b BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e CASTLE HILL HOSPITAL   (United Kingdom)

Author keywords

Genomic instability; Leukaemia; Neoplasia; Telomere fusion; Telomere length

Indexed keywords

ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CHROMOSOME ANALYSIS; CHRONIC LYMPHATIC LEUKEMIA; CYTOGENETICS; GENE; GENE MUTATION; GENETIC RISK; HAZARD RATIO; HIGH RESOLUTION SINGLE TELOMERE LENGTH ANALYSIS; HUMAN; HUMAN CELL; IGHV GENE; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PREDICTIVE VALUE; PRIORITY JOURNAL; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING; CLINICAL TRIAL; COHORT ANALYSIS; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MULTICENTER STUDY; MUTATION; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; SURVIVAL;

DNA; IMMUNOGLOBULIN VARIABLE REGION;

COHORT STUDIES; DNA, NEOPLASM; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MUTATION; NEOPLASM STAGING; PROGNOSIS; SURVIVAL ANALYSIS; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING;

EID: 84907533463     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13023     Document Type: Article

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