Prediction of cardiovascular risk using framingham, ASSIGN and QRISK2: How well do they predict individual rather than population risk?

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Van Staa, Tjeerd Pieter ^a,b,c   Gulliford, Martin ^d   Ng, Edmond S W ^b   Goldacre, Ben ^b   Smeeth, Liam ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UTRECHT UNIVERSITY   (Netherlands)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ADULT; AGED; ARTICLE; ASSIGN RISK SCORE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIABETES MELLITUS; ELECTRONIC MEDICAL RECORD; ETHNIC DIFFERENCE; FEMALE; FRAMINGHAM RISK SCORE; HUMAN; INDIVIDUALITY; MAJOR CLINICAL STUDY; MALE; POPULATION RISK; PREDICTION; PRESCRIPTION; QRISK2 RISK SCORE; SCORING SYSTEM; UNITED KINGDOM; CARDIOVASCULAR DISEASES; COMORBIDITY; HEALTH SURVEY; MIDDLE AGED; RISK; RISK ASSESSMENT; RISK FACTOR; STATISTICAL MODEL;

ADULT; AGED; CARDIOVASCULAR DISEASES; COMORBIDITY; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; POPULATION SURVEILLANCE; RISK; RISK ASSESSMENT; RISK FACTORS;

EID: 84907487248     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106455     Document Type: Article

References (27)

1. Taylor F, Ward K, Moore TH, Burke M, Davey Smith G, et al. (2011) Statins for the primary prevention of cardiovascular disease. Cochrane database Syst Rev: CD004816. Available: http://www.ncbi.nlm.nih.gov/pubmed/21249663. Accessed 2013 December 26.
2. Cooper A, Nherera L, Calvert N, O'Flynn N, Turnbull N, et al. (2007) Clinical Guidelines and Evidence Review for Lipid Modification: cardiovascular risk assessment and the primary and secondary prevention of cardiovascular disease. Available: http://www.nice.org.uk/nicemedia/pdf/CG67fullguideline.pdf.
3. JBS 2: Joint British Societies' guidelines on prevention of cardiovascular disease in clinical practice (2005) Heart 91 Suppl 5: v1-52. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1876394&tool=pmcentrez&rendertype=abstract. Accessed 2013 December 16.
4. Matheny M, McPheeters ML, Glasser A, Mercaldo N, Weaver RB, et al. (2011) Systematic review of cardiovascular disease risk assessment tools [Internet]. Rep No 11-05155-EF-1. Available: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list-uids=21796824.
5. Anderson KM, Odell PM, Wilson PWF, Kannel WB, Framingham MPH (n.d.) Cardiovascular disease risk profiles P (T > t) = p (log (;' -F > u}.
6. Woodward M, Brindle P, Tunstall-Pedoe H (2007). Adding social deprivation and family history to cardiovascular risk assessment: the ASSIGN score from the Scottish Heart Health Extended Cohort (SHHEC). Heart 93: 172-176. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1861393&tool=pmcentrez&rendertype=abstract. Accessed 2013 August 22.
7. Hippisley-Cox J, Coupland C, Vinogradova Y, Robson J, May M, et al. (2007) Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort study. BMJ 335: 136. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1925200&tool=pmcentrez&rendertype=abstract. Accessed 2013 August 19.
8. Hippisley-Cox J, Coupland C, Vinogradova Y, Robson J, Minhas R, et al. (2008) Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2. BMJ 336: 1475-1482. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2440904&tool=pmcentrez&rendertype=abstract. Accessed 2013 September 1.
9. Siontis GCM, Tzoulaki I, Ioannidis JPA (2012) Comparisons of established risk prediction models for cardiovascular disease: systematic review. 3318: 1-11. doi: 10.1136/bmj.e3318
10. Davies M, Khunti K, Webb D, Mostafa S, Gholap N, et al. (2012) Updated. The handbook for vascular risk assessment, risk reduction and risk management. Leicester.
11. Rose G (2008) Rose's strategy of preventive medicine. New York: Oxford University Press.
12. Williams T, van Staa TP, Puri S, Eaton S (2012). Recent advances in the utility and use of the General Practice Research Database as an example of a UK Primary Care Data resource. Ther Adv Drug Saf 3: 89-99.
13. Herrett E, Thomas SL, Schoonen WM, Smeeth L, Hall AJ (2010). Validation and validity of diagnoses in the General Practice Research Database: a systematic review. Br J Clin Pharmacol 69: 4-14. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2805870&tool=pmcentrez&rendertype=abstract. Accessed 2013 September 2.
14. Rubin DB (1987) Multiple imputation for nonresponse in surveys. New York: John Wiley.
15. Delaney JAC, Daskalopoulou SS, Brophy JM, Steele RJ, Opatrny L, et al. (2007) Lifestyle variables and the risk of myocardial infarction in the general practice research database. BMC Cardiovasc Disord 7: 38. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2241637&tool=pmcentrez&rendertype=abstract. Accessed 2014 June 20.
16. Cheng SC, Fine JP, Wei LJ (1998). Prediction of cumulative incidence function under the proportional hazards model. Biometrics 54: 219-228. Available: http://www.ncbi.nlm.nih.gov/pubmed/9544517.
17. Wolbers M, Koller MT, Witteman JCM, Steyerberg EW (2009). Prognostic models with competing risks: methods and application to coronary risk prediction. Epidemiology 20: 555-561. Available: http://www.ncbi.nlm.nih.gov/pubmed/19367167. Accessed 2013 August 12.
18. Royston P, Sauerbrei W (2008) Multivariable model-building: A pragmatic approach to regression analysis based on fractional polynomials for modelling continuous variables. Chichester: John Wiley & Sons, Ltd.
19. Altman DG, Vergouwe Y, Royston P, Moons KGM (2009) Prognosis and prognostic research: validating a prognostic model. BMJ 338: b605. Available: http://www.ncbi.nlm.nih.gov/pubmed/19477892. Accessed 2013 December 26.
20. McGraw K, Wong S (1996). Forming inferences about some intraclass correlation coefficients. Psychol Methods 1: 30-46.
21. Smolina K, Wright FL, Rayner M, Goldacre MJ (2012) Determinants of the decline in mortality from acute myocardial infarction in England between 2002 and 2010: linked national database study. BMJ 344: d8059. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3266430&tool=pmcentrez&rendertype=abstract. Accessed 26 December 2013.
22. Collins GS, Altman DG (2012) Predicting the 10 year risk of cardiovascular disease in the United Kingdom: independent and external validation of an updated version of QRISK2. 4181: 1-12. doi: 10.1136/bmj.e4181
23. Collins GS, Altman DG (2010) An independent and external validation of QRISK2 cardiovascular disease risk score: a prospective open cohort study. BMJ 340: c2442. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2869403&tool=pmcentrez&rendertype=abstract. Accessed 2013 December 26.
24. Mihaylova B, Emberson J, Blackwell L, Keech a, Simes J, et al. (2012). The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet 380: 581-590. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3437972&tool=pmcentrez&rendertype=abstract. Accessed 2013 August 9.
25. Ebrahim S, Casas JP (2012) Statins for all by the age of 50 years? Lancet 380: 545-547. Available: http://www.ncbi.nlm.nih.gov/pubmed/22607823. Accessed 2013 September 2.
26. Djulbegovic B, Paul A (2011). From efficacy to effectiveness in the face of uncertainty: indication creep and prevention creep. JAMA 305: 2005-2006. Available: http://www.ncbi.nlm.nih.gov/pubmed/21586716. Accessed 2013 December 26.
27. Gulliford MC, Charlton J, Ashworth M, Rudd AG, Toschke AM (2009) Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care database. PLoS One 4: e7168. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2744876&tool=pmcentrez&rendertype=abstract. Accessed 2013 September 2.