-
1
-
-
0036207969
-
Human cytomegalovirus terminase as a target for antiviral chemotherapy
-
E. Bogner Human cytomegalovirus terminase as a target for antiviral chemotherapy Rev. Med. Virol. 12 2002 115 127
-
(2002)
Rev. Med. Virol.
, vol.12
, pp. 115-127
-
-
Bogner, E.1
-
2
-
-
39749151703
-
The essential human cytomegalovirus gene UL52 is required for cleavage-packaging of the viral genome
-
E.M. Borst, K. Wagner, A. Binz, B. Sodeik, and M. Messerle The essential human cytomegalovirus gene UL52 is required for cleavage-packaging of the viral genome J. Virol. 82 2008 2065 2078
-
(2008)
J. Virol.
, vol.82
, pp. 2065-2078
-
-
Borst, E.M.1
Wagner, K.2
Binz, A.3
Sodeik, B.4
Messerle, M.5
-
3
-
-
84873054290
-
The human cytomegalovirus UL51 protein is essential for viral genome cleavage-packaging and interacts with the terminase subunits pUL56 and pUL89
-
E.M. Borst, J. Kleine-Albers, I. Gabaev, M. Babic, K. Wagner, A. Binz, I. Degenhardt, M. Kalesse, S. Jonjic, R. Bauerfeind, and M. Messerle The human cytomegalovirus UL51 protein is essential for viral genome cleavage-packaging and interacts with the terminase subunits pUL56 and pUL89 J. Virol. 87 2013 1720 1732
-
(2013)
J. Virol.
, vol.87
, pp. 1720-1732
-
-
Borst, E.M.1
Kleine-Albers, J.2
Gabaev, I.3
Babic, M.4
Wagner, K.5
Binz, A.6
Degenhardt, I.7
Kalesse, M.8
Jonjic, S.9
Bauerfeind, R.10
Messerle, M.11
-
4
-
-
58149457329
-
Resistance pattern of cytomegalovirus (CMV) after oral valganciclovir therapy in transplant recipients at high-risk for CMV infection
-
D. Boutolleau, C. Deback, C. Bressollette-Bodin, S. Varnous, N. Dhedin, B. Barrou, J.P. Vernant, I. Gandjbakhch, B.M. Imbert-Marcille, and H. Agut Resistance pattern of cytomegalovirus (CMV) after oral valganciclovir therapy in transplant recipients at high-risk for CMV infection Antiviral Res. 81 2009 174 179
-
(2009)
Antiviral Res.
, vol.81
, pp. 174-179
-
-
Boutolleau, D.1
Deback, C.2
Bressollette-Bodin, C.3
Varnous, S.4
Dhedin, N.5
Barrou, B.6
Vernant, J.P.7
Gandjbakhch, I.8
Imbert-Marcille, B.M.9
Agut, H.10
-
5
-
-
79957504008
-
Genotypic characterization of human cytomegalovirus UL97 phosphotransferase natural polymorphism in the era of ganciclovir and maribavir
-
D. Boutolleau, S. Burrel, and H. Agut Genotypic characterization of human cytomegalovirus UL97 phosphotransferase natural polymorphism in the era of ganciclovir and maribavir Antiviral Res. 91 2011 32 35
-
(2011)
Antiviral Res.
, vol.91
, pp. 32-35
-
-
Boutolleau, D.1
Burrel, S.2
Agut, H.3
-
6
-
-
34147180601
-
New functional domains of human cytomegalovirus pUL89 predicted by sequence analysis and three-dimensional modeling of the catalytic site DEXDc
-
G. Champier, S. Hantz, A. Couvreux, S. Stuppfler, M.C. Mazeron, S. Bouaziz, F. Denis, and S. Alain New functional domains of human cytomegalovirus pUL89 predicted by sequence analysis and three-dimensional modeling of the catalytic site DEXDc Antivir. Ther. 12 2007 217 232
-
(2007)
Antivir. Ther.
, vol.12
, pp. 217-232
-
-
Champier, G.1
Hantz, S.2
Couvreux, A.3
Stuppfler, S.4
Mazeron, M.C.5
Bouaziz, S.6
Denis, F.7
Alain, S.8
-
7
-
-
49949098917
-
Putative functional domains of human cytomegalovirus pUL56 involved in dimerization and benzimidazole D-ribonucleoside activity
-
G. Champier, A. Couvreux, S. Hantz, A. Rametti, M.C. Mazeron, S. Bouaziz, F. Denis, and S. Alain Putative functional domains of human cytomegalovirus pUL56 involved in dimerization and benzimidazole D-ribonucleoside activity Antivir. Ther. 13 2008 643 654
-
(2008)
Antivir. Ther.
, vol.13
, pp. 643-654
-
-
Champier, G.1
Couvreux, A.2
Hantz, S.3
Rametti, A.4
Mazeron, M.C.5
Bouaziz, S.6
Denis, F.7
Alain, S.8
-
8
-
-
84899819902
-
Letermovir for cytomegalovirus prophylaxis in hematopoietic-cell transplantation
-
R.F. Chemaly, A.J. Ullmann, S. Stoelben, M.P. Richard, M. Bornhäuser, C. Groth, H. Einsele, M. Silverman, K.M. Mullane, J. Brown, H. Nowak, K. Kölling, H.P. Stobernack, P. Lischka, H. Zimmermann, H. Rübsamen-Schaeff, R.E. Champlin, G. Ehninger, and AIC246 Study Team Letermovir for cytomegalovirus prophylaxis in hematopoietic-cell transplantation N. Engl. J. Med. 370 2004 1781 1789
-
(2004)
N. Engl. J. Med.
, vol.370
, pp. 1781-1789
-
-
Chemaly, R.F.1
Ullmann, A.J.2
Stoelben, S.3
Richard, M.P.4
Bornhäuser, M.5
Groth, C.6
Einsele, H.7
Silverman, M.8
Mullane, K.M.9
Brown, J.10
Nowak, H.11
Kölling, K.12
Stobernack, H.P.13
Lischka, P.14
Zimmermann, H.15
Rübsamen-Schaeff, H.16
Champlin, R.E.17
Ehninger, G.18
Study Team, A.19
-
9
-
-
0033063981
-
Interstrain variation in the human cytomegalovirus DNA polymerase sequence and its effect on genotypic diagnosis of antiviral drug resistance
-
Aids Trials Group Cmv Laboratories A.
-
S. Chou, N.S. Lurain, A. Weinberg, G.Y. Cai, P.L. Sharma, C.S. Crumpacker, and Adult AIDS Trials Group CMV Laboratories Interstrain variation in the human cytomegalovirus DNA polymerase sequence and its effect on genotypic diagnosis of antiviral drug resistance Antimicrob. Agents Chemother. 43 1999 1500 1502
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 1500-1502
-
-
Chou, S.1
Lurain, N.S.2
Weinberg, A.3
Cai, G.Y.4
Sharma, P.L.5
Crumpacker, C.S.6
-
10
-
-
27744431876
-
Interaction of the putative cytomegalovirus portal protein pUL104 with the large terminase subunit pUL56 and its inhibition by benzimidazole-D-ribonucleosides
-
A. Dittmer, J.C. Drach, L.B. Townsend, A. Fischer, and E. Bogner Interaction of the putative cytomegalovirus portal protein pUL104 with the large terminase subunit pUL56 and its inhibition by benzimidazole-D-ribonucleosides J. Virol. 79 2005 14660 14667
-
(2005)
J. Virol.
, vol.79
, pp. 14660-14667
-
-
Dittmer, A.1
Drach, J.C.2
Townsend, L.B.3
Fischer, A.4
Bogner, E.5
-
11
-
-
11144354380
-
Natural polymorphism of cytomegalovirus DNA polymerase lies in two nonconserved regions located between domains delta-C and II and between III and i
-
A.M. Fillet, L. Auray, S. Alain, S. Gourlain, B.M. Imbert, F. Najioullah, G. Champier, S. Gouarin, J. Carquin, N. Houhou, I. Garrigue, A. Ducancelle, D. Thouvenot, and M.C. Mazeron Natural polymorphism of cytomegalovirus DNA polymerase lies in two nonconserved regions located between domains delta-C and II and between III and I Antimicrob. Agents Chemother. 48 2004 1865 1868
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 1865-1868
-
-
Fillet, A.M.1
Auray, L.2
Alain, S.3
Gourlain, S.4
Imbert, B.M.5
Najioullah, F.6
Champier, G.7
Gouarin, S.8
Carquin, J.9
Houhou, N.10
Garrigue, I.11
Ducancelle, A.12
Thouvenot, D.13
Mazeron, M.C.14
-
12
-
-
80055021608
-
The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase
-
T. Goldner, G. Hewlett, N. Ettischer, H. Ruebsamen-Schaeff, H. Zimmermann, and P. Lischka The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase J. Virol. 85 2011 10884 10893
-
(2011)
J. Virol.
, vol.85
, pp. 10884-10893
-
-
Goldner, T.1
Hewlett, G.2
Ettischer, N.3
Ruebsamen-Schaeff, H.4
Zimmermann, H.5
Lischka, P.6
-
13
-
-
84891504725
-
Geno- and phenotypic characterization of human cytomegalovirus mutants selected in vitro after letermovir (AIC246) exposure
-
T. Goldner, C. Hempel, H. Ruebsamen-Schaeff, H. Zimmermann, and P. Lischka Geno- and phenotypic characterization of human cytomegalovirus mutants selected in vitro after letermovir (AIC246) exposure Antimicrob. Agents Chemother. 58 2014 610 613
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 610-613
-
-
Goldner, T.1
Hempel, C.2
Ruebsamen-Schaeff, H.3
Zimmermann, H.4
Lischka, P.5
-
14
-
-
79955544310
-
First report of successful treatment of multidrug-resistant cytomegalovirus disease with the novel anti-CMV compound AIC246
-
D.R. Kaul, S. Stoelben, E. Cober, T. Ojo, E. Sandusky, P. Lischka, H. Zimmermann, and H. Ruebsamen-Schaeff First report of successful treatment of multidrug-resistant cytomegalovirus disease with the novel anti-CMV compound AIC246 Am. J. Transplant. 11 2001 1079 1084
-
(2001)
Am. J. Transplant.
, vol.11
, pp. 1079-1084
-
-
Kaul, D.R.1
Stoelben, S.2
Cober, E.3
Ojo, T.4
Sandusky, E.5
Lischka, P.6
Zimmermann, H.7
Ruebsamen-Schaeff, H.8
-
15
-
-
0346688644
-
Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides
-
G. Komazin, L.B. Townsend, and J.C. Drach Role of a mutation in human cytomegalovirus gene UL104 in resistance to benzimidazole ribonucleosides J. Virol. 78 2004 710 715
-
(2004)
J. Virol.
, vol.78
, pp. 710-715
-
-
Komazin, G.1
Townsend, L.B.2
Drach, J.C.3
-
16
-
-
0031946070
-
Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56
-
P.M. Krosky, M.R. Underwood, S.R. Turk, K.W. Feng, R.K. Jai, R.G. Ptak, A.C. Westerman, K.K. Biron, L.B. Towsend, and J.C. Drach Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56 J. Virol. 72 1998 4721 4728
-
(1998)
J. Virol.
, vol.72
, pp. 4721-4728
-
-
Krosky, P.M.1
Underwood, M.R.2
Turk, S.R.3
Feng, K.W.4
Jai, R.K.5
Ptak, R.G.6
Westerman, A.C.7
Biron, K.K.8
Towsend, L.B.9
Drach, J.C.10
-
17
-
-
54849431773
-
Antiviral strategies to combat cytomegalovirus infections in transplant recipients
-
P. Lischka, and H. Zimmermann Antiviral strategies to combat cytomegalovirus infections in transplant recipients Curr. Opin. Pharmacol. 8 2008 541 548
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 541-548
-
-
Lischka, P.1
Zimmermann, H.2
-
18
-
-
77149133052
-
In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246
-
P. Lischka, G. Hewlett, T. Wunberg, J. Baumeister, D. Paulsen, T. Goldner, H. Ruebsamen-Schaeff, and H. Zimmermann In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246 Antimicrob. Agents Chemother. 54 2010 1290 1297
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 1290-1297
-
-
Lischka, P.1
Hewlett, G.2
Wunberg, T.3
Baumeister, J.4
Paulsen, D.5
Goldner, T.6
Ruebsamen-Schaeff, H.7
Zimmermann, H.8
-
19
-
-
78049355534
-
Antiviral drug resistance of human cytomegalovirus
-
N.S. Lurain, and S. Chou Antiviral drug resistance of human cytomegalovirus Clin. Microbiol. Rev. 23 2010 689 712
-
(2010)
Clin. Microbiol. Rev.
, vol.23
, pp. 689-712
-
-
Lurain, N.S.1
Chou, S.2
-
20
-
-
84856074080
-
In vitro evaluation of the activities of the novel anticytomegalovirus compound AIC246 (Letermovir) against herpesviruses and other human pathogenic viruses
-
M. Marschall, T. Stamminger, A. Urban, S. Wildum, H. Ruebsamen-Schaeff, H. Zimmermann, and P. Lischka In vitro evaluation of the activities of the novel anticytomegalovirus compound AIC246 (Letermovir) against herpesviruses and other human pathogenic viruses Antimicrob. Agents Chemother. 56 2012 1135 1137
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 1135-1137
-
-
Marschall, M.1
Stamminger, T.2
Urban, A.3
Wildum, S.4
Ruebsamen-Schaeff, H.5
Zimmermann, H.6
Lischka, P.7
-
21
-
-
0035656411
-
Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766): In vitro and in vivo antiviral activity and mechanism of action
-
J. Reefschlaeger, W. Bender, S. Hallenberger, O. Weber, P. Eckenberg, S. Goldmann, M. Haerter, I. Buerger, J. Trappe, J.A. Herrington, D. Haebich, and H. Ruebsamen-Waigmann Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766): in vitro and in vivo antiviral activity and mechanism of action J. Antimicrob. Chemother. 48 2001 757 767
-
(2001)
J. Antimicrob. Chemother.
, vol.48
, pp. 757-767
-
-
Reefschlaeger, J.1
Bender, W.2
Hallenberger, S.3
Weber, O.4
Eckenberg, P.5
Goldmann, S.6
Haerter, M.7
Buerger, I.8
Trappe, J.9
Herrington, J.A.10
Haebich, D.11
Ruebsamen-Waigmann, H.12
-
22
-
-
84896497988
-
Pre-emptive treatment of cytomegalovirus infection in kidney transplant recipients with letermovir: Results of a phase 2a study
-
S. Stoelben, W. Arns, L. Renders, J. Hummel, A. Mühlfeld, M. Stangl, M. Fischereder, W. Gwinner, B. Suwelack, O. Witzke, M. Dürr, D. Beelen, D. Michel, P. Lischka, H. Zimmermann, H. Ruebsamen-Schaeff, and K. Budde Pre-emptive treatment of cytomegalovirus infection in kidney transplant recipients with letermovir: results of a phase 2a study Transpl. Int. 27 2014 77 86
-
(2014)
Transpl. Int.
, vol.27
, pp. 77-86
-
-
Stoelben, S.1
Arns, W.2
Renders, L.3
Hummel, J.4
Mühlfeld, A.5
Stangl, M.6
Fischereder, M.7
Gwinner, W.8
Suwelack, B.9
Witzke, O.10
Dürr, M.11
Beelen, D.12
Michel, D.13
Lischka, P.14
Zimmermann, H.15
Ruebsamen-Schaeff, H.16
Budde, K.17
|