GLP-1 agonist therapy for advanced heart failure with reduced ejection fraction design and rationale for the functional impact of GLP-1 for heart failure treatment study

Circulation: Heart Failure

Volumn 7, Issue 4, 2014, Pages 673-679

  Margulies, Kenneth B ^a   Anstrom, Kevin J ^b   Hernandez, Adrian F ^b   Redfield, Margaret M ^c   Shah, Monica R ^d   Braunwald, Eugene ^e   Cappola, Thomas P ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c MAYO CLINIC   (United States)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Clinical trial; Glucagon like peptide 1; Heart failure; Insulin resistance

Indexed keywords

C REACTIVE PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; FATTY ACID; FUROSEMIDE; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; GLUCOSE; LIRAGLUTIDE; ANTIDIABETIC AGENT; INSULIN;

ACUTE CORONARY SYNDROME; ACUTE HEART FAILURE; ARTICLE; FATTY ACID OXIDATION; FOLLOW UP; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; GLYCEMIC CONTROL; HEART EJECTION FRACTION; HEART FAILURE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; HEART MUSCLE METABOLISM; HEART VENTRICLE HYPERTROPHY; HOSPITAL PATIENT; HOSPITAL READMISSION; HOSPITALIZATION; HYDROLYSIS; IN VITRO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTENTION TO TREAT ANALYSIS; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZATION; RANK SUM TEST; RESTRICTIVE CARDIOMYOPATHY; SAMPLE SIZE; UNITED STATES; ANIMAL; CLINICAL TRIAL; CLINICAL TRIAL (TOPIC); DRUG EFFECT; DRUG POTENTIATION; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; HUMAN; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; REVIEW; TREATMENT OUTCOME;

CLINICAL TRIAL; GLUCAGON-LIKE PEPTIDE-1; HEART FAILURE; INSULIN RESISTANCE;

ANIMALS; CLINICAL TRIALS AS TOPIC; GLUCAGON-LIKE PEPTIDE 1; HEART FAILURE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; STROKE VOLUME; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT;

EID: 84907420900     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.114.000346     Document Type: Article

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