-
1
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014; 64: 9-29
-
(2014)
CA Cancer J Clin
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
2
-
-
77951755278
-
Pancreatic cancer
-
Hidalgo M. Pancreatic cancer. New Engl J Med 2010; 362: 1605-1617
-
(2010)
New Engl J Med
, vol.362
, pp. 1605-1617
-
-
Hidalgo, M.1
-
3
-
-
67650924582
-
Pancreatic cancer: Molecular pathogenesis and new therapeutic targets
-
Wong HH, Lemoine NR. Pancreatic cancer: molecular pathogenesis and new therapeutic targets. Nat Rev Gastroenterol Hepatol 2009; 6: 412-422
-
(2009)
Nat Rev Gastroenterol Hepatol
, vol.6
, pp. 412-422
-
-
Wong, H.H.1
Lemoine, N.R.2
-
4
-
-
0028799821
-
Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression
-
Friess H, Yamanaka Y, Kobrin MS, Do DA, Buchler MW, Korc M. Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression. Clin Cancer Res 1995; 1: 1413-1420
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1413-1420
-
-
Friess, H.1
Yamanaka, Y.2
Kobrin, M.S.3
Do, D.A.4
Buchler, M.W.5
Korc, M.6
-
5
-
-
34250647865
-
In vivo therapeutic synergism of anti-epidermal growth factor receptor and anti-HER2 monoclonal antibodies against pancreatic carcinomas
-
Larbouret C, Robert B, Navarro-Teulon I, Thezenas S, Ladjemi MZ, Morisseau S et al. In vivo therapeutic synergism of anti-epidermal growth factor receptor and anti-HER2 monoclonal antibodies against pancreatic carcinomas. Clin Cancer Res 2007; 13: 3356-3362
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3356-3362
-
-
Larbouret, C.1
Robert, B.2
Navarro-Teulon, I.3
Thezenas, S.4
Ladjemi, M.Z.5
Morisseau, S.6
-
6
-
-
24144457548
-
Assessment of HER-2 status in pancreatic adenocarcinoma: Correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival
-
Saxby AJ, Nielsen A, Scarlett CJ, Clarkson A, Morey A, Gill A et al. Assessment of HER-2 status in pancreatic adenocarcinoma: correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival. Am J Surg Pathol 2005; 29: 1125-1134
-
(2005)
Am J Surg Pathol
, vol.29
, pp. 1125-1134
-
-
Saxby, A.J.1
Nielsen, A.2
Scarlett, C.J.3
Clarkson, A.4
Morey, A.5
Gill, A.6
-
7
-
-
4143128359
-
Epidermal growth factor receptor expression in human pancreatic cancer: Significance for liver metastasis
-
Tobita K, Kijima H, Dowaki S, Kashiwagi H, Ohtani Y, Oida Y et al. Epidermal growth factor receptor expression in human pancreatic cancer: Significance for liver metastasis. Int J Mol Med 2003; 11: 305-309
-
(2003)
Int J Mol Med
, vol.11
, pp. 305-309
-
-
Tobita, K.1
Kijima, H.2
Dowaki, S.3
Kashiwagi, H.4
Ohtani, Y.5
Oida, Y.6
-
8
-
-
19944429073
-
Herceptin and gemcitabine for metastatic pancreatic cancers that overexpress HER-2/neu
-
Safran H, Iannitti D, Ramanathan R, Schwartz JD, Steinhoff M, Nauman C et al. Herceptin and gemcitabine for metastatic pancreatic cancers that overexpress HER-2/neu. Cancer Invest 2004; 22: 706-712
-
(2004)
Cancer Invest
, vol.22
, pp. 706-712
-
-
Safran, H.1
Iannitti, D.2
Ramanathan, R.3
Schwartz, J.D.4
Steinhoff, M.5
Nauman, C.6
-
9
-
-
77955914277
-
Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205
-
Philip PA, Benedetti J, Corless CL, Wong R, O'Reilly EM, Flynn PJ et al. Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205. J Clin Oncol 2010; 28: 3605-3610
-
(2010)
J Clin Oncol
, vol.28
, pp. 3605-3610
-
-
Philip, P.A.1
Benedetti, J.2
Corless, C.L.3
Wong, R.4
O'Reilly, E.M.5
Flynn, P.J.6
-
10
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
Moore MJ, Goldstein D, Hamm J, Figer A, Hecht JR, Gallinger S et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007; 25: 1960-1966
-
(2007)
J Clin Oncol
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
Figer, A.4
Hecht, J.R.5
Gallinger, S.6
-
11
-
-
77950628416
-
Mechanisms of resistance to HER family targeting antibodies
-
Kruser TJ, Wheeler DL. Mechanisms of resistance to HER family targeting antibodies. Exp Cell Res 2010; 316: 1083-1100
-
(2010)
Exp Cell Res
, vol.316
, pp. 1083-1100
-
-
Kruser, T.J.1
Wheeler, D.L.2
-
12
-
-
5044221199
-
The efficacy of Herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins
-
Smith BL, Chin D, Maltzman W, Crosby K, Hortobagyi GN, Bacus SS. The efficacy of Herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins. Br J Cancer 2004; 91: 1190-1194
-
(2004)
Br J Cancer
, vol.91
, pp. 1190-1194
-
-
Smith, B.L.1
Chin, D.2
Maltzman, W.3
Crosby, K.4
Hortobagyi, G.N.5
Bacus, S.S.6
-
13
-
-
84864286442
-
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
-
Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature 2012; 487: 505-509
-
(2012)
Nature
, vol.487
, pp. 505-509
-
-
Wilson, T.R.1
Fridlyand, J.2
Yan, Y.3
Penuel, E.4
Burton, L.5
Chan, E.6
-
14
-
-
84864367360
-
The ERBB network: At last, cancer therapy meets systems biology
-
Yarden Y, Pines G. The ERBB network: at last, cancer therapy meets systems biology. Nat Rev Cancer 2012; 12: 553-563
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 553-563
-
-
Yarden, Y.1
Pines, G.2
-
15
-
-
80051596515
-
Targeting ErbB3-mediated stromal-epithelial interactions in pancreatic ductal adenocarcinoma
-
Liles JS, Arnoletti JP, Kossenkov AV, Mikhaylina A, Frost AR, Kulesza P et al. Targeting ErbB3-mediated stromal-epithelial interactions in pancreatic ductal adenocarcinoma. Br J Cancer 2011; 105: 523-533
-
(2011)
Br J Cancer
, vol.105
, pp. 523-533
-
-
Liles, J.S.1
Arnoletti, J.P.2
Kossenkov, A.V.3
Mikhaylina, A.4
Frost, A.R.5
Kulesza, P.6
-
16
-
-
34548251394
-
ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib
-
Frolov A, Schuller K, Tzeng CW, Cannon EE, Ku BC, Howard JH et al. ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib. Cancer Biol Ther 2007; 6: 548-554
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 548-554
-
-
Frolov, A.1
Schuller, K.2
Tzeng, C.W.3
Cannon, E.E.4
Ku, B.C.5
Howard, J.H.6
-
17
-
-
77957128233
-
ErbB3 expression promotes tumorigenesis in pancreatic adenocarcinoma
-
Liles JS, Arnoletti JP, Tzeng CW, Howard JH, Kossenkov AV, Kulesza P et al. ErbB3 expression promotes tumorigenesis in pancreatic adenocarcinoma. Cancer Biol Ther 2010; 10: 555-563
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 555-563
-
-
Liles, J.S.1
Arnoletti, J.P.2
Tzeng, C.W.3
Howard, J.H.4
Kossenkov, A.V.5
Kulesza, P.6
-
18
-
-
33845691807
-
Expression and differential signaling of heregulins in pancreatic cancer cells
-
Kolb A, Kleeff J, Arnold N, Giese NA, Giese T, Korc M et al. Expression and differential signaling of heregulins in pancreatic cancer cells. Int J Cancer 2007; 120: 514-523
-
(2007)
Int J Cancer
, vol.120
, pp. 514-523
-
-
Kolb, A.1
Kleeff, J.2
Arnold, N.3
Giese, N.A.4
Giese, T.5
Korc, M.6
-
19
-
-
77952338791
-
ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation
-
Shi F, Telesco SE, Liu Y, Radhakrishnan R, Lemmon MA. ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation. Proc Natl Acad Sci USA 2010; 107: 7692-7697
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7692-7697
-
-
Shi, F.1
Telesco, S.E.2
Liu, Y.3
Radhakrishnan, R.4
Lemmon, M.A.5
-
20
-
-
0029053716
-
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
-
Alimandi M, Romano A, Curia MC, Muraro R, Fedi P, Aaronson SA et al. Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 1995; 10: 1813-1821
-
(1995)
Oncogene
, vol.10
, pp. 1813-1821
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
Muraro, R.4
Fedi, P.5
Aaronson, S.A.6
-
21
-
-
0037429779
-
The deaf and the dumb: The biology of ErbB-2 and ErbB-3
-
Citri A, Skaria KB, Yarden Y. The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp Cell Res 2003; 284: 54-65
-
(2003)
Exp Cell Res
, vol.284
, pp. 54-65
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
22
-
-
84858006197
-
An ErbB-3 antibody, MP-RM-1, inhibits tumor growth by blocking ligand-dependent and independent activation of ErbB-3/Akt signaling
-
Sala G, Traini S, D'Egidio M, Vianale G, Rossi C, Piccolo E et al. An ErbB-3 antibody, MP-RM-1, inhibits tumor growth by blocking ligand-dependent and independent activation of ErbB-3/Akt signaling. Oncogene 2012; 31: 1275-1286
-
(2012)
Oncogene
, vol.31
, pp. 1275-1286
-
-
Sala, G.1
Traini, S.2
D'Egidio, M.3
Vianale, G.4
Rossi, C.5
Piccolo, E.6
-
23
-
-
84891683320
-
EV20, a novel Anti-ErbB-3 humanized antibody, promotes ErbB-3 down-regulation and inhibits tumor growth in vivo
-
Sala G, Rapposelli IG, Ghasemi R, Piccolo E, Traini S, Capone E et al. EV20, a novel Anti-ErbB-3 humanized antibody, promotes ErbB-3 down-regulation and inhibits tumor growth in vivo. Transl Oncol 2013; 6: 676-684
-
(2013)
Transl Oncol
, vol.6
, pp. 676-684
-
-
Sala, G.1
Rapposelli, I.G.2
Ghasemi, R.3
Piccolo, E.4
Traini, S.5
Capone, E.6
-
24
-
-
80053539103
-
Adjuvant trastuzumab in HER2-positive breast cancer
-
Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M et al. Adjuvant trastuzumab in HER2-positive breast cancer. New Engl J Med 2011; 365: 1273-1283
-
(2011)
New Engl J Med
, vol.365
, pp. 1273-1283
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
Pienkowski, T.4
Martin, M.5
Press, M.6
-
25
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010; 376: 687-697
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
Chung, H.C.4
Shen, L.5
Sawaki, A.6
-
26
-
-
0028949081
-
Heregulin Stimulates Mitogenesis and Phosphatidylinositol 3-Kinase in Mouse Fibroblasts Transfected with erbB2/neu and erbB3
-
Carraway KL, Soltoff SP, Diamonti AJ, Cantley LC. Heregulin Stimulates Mitogenesis and Phosphatidylinositol 3-Kinase in Mouse Fibroblasts Transfected with erbB2/neu and erbB3. J Biol Chem 1995; 270: 7111-7116
-
(1995)
J Biol Chem
, vol.270
, pp. 7111-7116
-
-
Carraway, K.L.1
Soltoff, S.P.2
Diamonti, A.J.3
Cantley, L.C.4
-
27
-
-
62649159075
-
Ligand-induced ErbB receptor dimerization
-
Lemmon MA. Ligand-induced ErbB receptor dimerization. Exp Cell Res 2009; 315: 638-648
-
(2009)
Exp Cell Res
, vol.315
, pp. 638-648
-
-
Lemmon, M.A.1
-
28
-
-
33748361817
-
Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity
-
Buck E, Eyzaguirre A, Haley JD, Gibson NW, Cagnoni P, Iwata KK. Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity. Mol Cancer Ther 2006; 5: 2051-2059
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2051-2059
-
-
Buck, E.1
Eyzaguirre, A.2
Haley, J.D.3
Gibson, N.W.4
Cagnoni, P.5
Iwata, K.K.6
-
29
-
-
67649472398
-
Novel anticancer targets: Revisiting ERBB2 and discovering ERBB3
-
Baselga J, Swain SM. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer 2009; 9: 463-475
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 463-475
-
-
Baselga, J.1
Swain, S.M.2
-
30
-
-
84897743013
-
Role of erbB3 receptors in cancer therapeutic resistance
-
Lee Y, Ma J, Lyu H, Huang J, Kim A, Liu B. Role of erbB3 receptors in cancer therapeutic resistance. Acta Biochim Biophys Sin (Shanghai) 2014; 46: 190-198
-
(2014)
Acta Biochim Biophys Sin (Shanghai)
, vol.46
, pp. 190-198
-
-
Lee, Y.1
Ma, J.2
Lyu, H.3
Huang, J.4
Kim, A.5
Liu, B.6
|