Variability in compounding of oral liquids for pediatric patients: A patient safety concern

Journal of the American Pharmacists Association

Volumn 54, Issue 4, 2014, Pages 383-389

  Rood, Janis M ^a   Engels, Melanie J ^b   Ciarkowski, Scott L ^c   Wagenknecht, Larry D ^d   Dickinson, Chris J ^e   Stevenson, James G ^c,f  

^a Plymouth Pharmacy and Medical Supplies   (United States)

^b UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d Michigan Pharmacists Association   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Current pharmacy practices; Drug compounding; Formulations; Oral liquids; Patient safety; Pediatrics

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; APREPITANT; BACLOFEN; BOSENTAN; BUSULFAN; CALCIFEDIOL; CANDESARTAN; CARBENICILLIN; CARDIOVASCULAR AGENT; CLOTRIMAZOLE; COLESTYRAMINE; DAPSONE; DIPYRIDAMOLE; ENCAINIDE; ETACRYNIC ACID; GASTROINTESTINAL AGENT; LOSARTAN; METRONIDAZOLE; MORPHINE SULFATE; POLYMYXIN; PRAVASTATIN; PROCARBAZINE; PROPAFENONE; PROPYLTHIOURACIL; QUETIAPINE; RIFABUTIN; STEROID; THIAZIDE DIURETIC AGENT; UNINDEXED DRUG; SOLUTION AND SOLUBILITY;

ARTICLE; CAREGIVER; CHILD; CHILD HEALTH CARE; CROSS-SECTIONAL STUDY; DRUG FORMULATION; E-MAIL; HOSPITAL PATIENT; HOSPITAL PHARMACY; HUMAN; INFANT; LIQUID; MEDICATION ERROR; NEWBORN; ONLINE SYSTEM; OUTPATIENT; PATIENT SAFETY; PEDIATRIC HOSPITAL; PHARMACY; PRESCRIPTION; PROFESSIONAL PRACTICE; QUESTIONNAIRE; UNITED STATES; ADVERSE EFFECTS; CHEMISTRY; ORAL DRUG ADMINISTRATION; PEDIATRICS; PHARMACIST; SOLUTION AND SOLUBILITY; THERAPEUTIC USE;

ADMINISTRATION, ORAL; COMMUNITY PHARMACY SERVICES; CROSS-SECTIONAL STUDIES; DRUG COMPOUNDING; HUMANS; MEDICATION ERRORS; MICHIGAN; PATIENT SAFETY; PEDIATRICS; PHARMACEUTICAL SERVICES; PHARMACEUTICAL SOLUTIONS; PHARMACIES; PHARMACISTS;

EID: 84907317399     PISSN: 15443191     EISSN: 15443450     Source Type: Journal    
DOI: 10.1331/JAPhA.2014.13074     Document Type: Article

References (6)

1. The Joint Commission. Sentinel Event Alert, issue 39, April 11, 2008. Preventing pediatric medication errors. www.jointcommission.org/assets/1/18/SEA- 39.pdf. Accessed December 14, 2012.
2. Consumer Healthcare Products Association. OTC industry announces voluntary transition to one concentration of single-ingredient pediatric liquid acetaminophen medicines. www.chpa.org/05-04-11-PedAcet.aspx. Accessed December 14, 2012.
3. Consumer Healthcare Products Association. OTC industry supports FDA advisory committee recommendations on new dosing instructions. www.chpa.org/05-18-11newdosinginstructions.aspx. Accessed December 14, 2012.
4. Thompson KC. Extemporaneous formulations: comparison with labeled pediatric formulations. Am Pharm Rev. 2010;13(2).
5. Engels M, Ciarkowski S, Wagenknecht L, et al. A statewide pediatric safety collaboration to standardize compounded oral liquids. Michigan Pharmacist. 2012;50(1):28-29.
6. Doherty C, McDonnell C. Tenfold medication errors: 5 years' experience at a university-affiliated pediatric hospital. Pediatrics. 2012;129(5):916-924.