Subchronic treatment of donepezil rescues impaired social, hyperactive, and stereotypic behavior in valproic acid-induced animal model of autism

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Kim, Ji Woon ^a   Seung, Hana ^a   Kwon, Kyung Ja ^b   Ko, Mee Jung ^a   Lee, Eun Joo ^a   Oh, Hyun Ah ^a   Choi, Chang Soon ^a   Kim, Ki Chan ^a   Gonzales, Edson Luck ^a   You, Jueng Soo ^a   Choi, Dong Hee ^a   Lee, Jongmin ^a   Han, Seol Heui ^a   Yang, Sung Min ^a   Cheong, Jae Hoon ^c   Shin, Chan Young ^a   Bahn, Geon Ho ^d  

^a Konkuk University School of Medicine   (South Korea)

^b Konkuk University   (South Korea)

^c Sahmyook University   (South Korea)

^d Kyung Hee University Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; DONEPEZIL; HISTONE H3; VALPROIC ACID; HISTONE; INDAN DERIVATIVE; PIPERIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BEHAVIOR DISORDER; CHOLINERGIC NERVE CELL; COMPULSION; CONTROLLED STUDY; DRUG EFFECT; DRUG TARGETING; EMBRYO; FEMALE; HISTONE ACETYLATION; HYPERACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL CULTURE; NEURAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PREFRONTAL CORTEX; PRENATAL DRUG EXPOSURE; PROMOTER REGION; PROTEIN EXPRESSION; RAT; SOCIAL BEHAVIOR; STEREOTYPY; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; AUTISTIC DISORDER; CELL CULTURE; CHEMICALLY INDUCED; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODEL; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PREGNANCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ACETYLCHOLINESTERASE; ANIMALS; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODELS, ANIMAL; FEMALE; HISTONES; IMMUNOHISTOCHEMISTRY; INDANS; MICE, INBRED ICR; PIPERIDINES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEREOTYPED BEHAVIOR; VALPROIC ACID;

EID: 84907261802     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104927     Document Type: Article

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