Prevalence of CKD and its relationship to eGFR-related genetic loci and clinical risk factors in the SardiNIA study cohort

Journal of the American Society of Nephrology

Volumn 25, Issue 7, 2014, Pages 1533-1544

  Pani, Antonello ^a   Bragg Gresham, Jennifer ^b   Masala, Marco ^c   Piras, Doloretta ^a   Atzeni, Alice ^a   Pilia, Maria G ^d   Ferreli, Liana ^d   Balaci, Lenuta ^d   Curreli, Nicolò ^d   Delitala, Alessandro ^d   Loi, Francesco ^d   Abecasis, Gonçalo R ^b   Schlessinger, David ^e   Cucca, Francesco ^c,f  

^a BROTZU HOSPITAL   (Italy)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Milan Unit   (Italy)

^d CNR   (Italy)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f UNIVERSITY OF SASSARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLELE; ARTICLE; CHRONIC KIDNEY DISEASE; COHORT ANALYSIS; CROSS-SECTIONAL STUDY; ECHOGRAPHY; FEMALE; FOLLOW UP; GENE LOCUS; GENETIC RISK; GENETIC VARIABILITY; GLOMERULUS FILTRATION RATE; GROUPS BY AGE; HEART DISEASE; HUMAN; HYPERTENSION; HYPERURICEMIA; KIDNEY FUNCTION; KIDNEY SIZE; LONGITUDINAL STUDY; MACROALBUMINURIA; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MICROALBUMINURIA; PRACTICE GUIDELINE; PRIORITY JOURNAL; RISK FACTOR; AGED; CHRONIC KIDNEY FAILURE; EPIDEMIOLOGY; ETHNICITY; GENETICS; HUMAN GENETICS; ITALY; MIDDLE AGED; PATHOPHYSIOLOGY; PREVALENCE; RENAL FUNCTION DECLINE; YOUNG ADULT;

CHRONIC KIDNEY DISEASE; CLINICAL EPIDEMIOLOGY; ETHNICITY; GLOMERULAR FILTRATION RATE; HUMAN GENETICS; RENAL FUNCTION DECLINE;

ADULT; AGED; COHORT STUDIES; FEMALE; GENETIC LOCI; GLOMERULAR FILTRATION RATE; HUMANS; ITALY; MALE; MIDDLE AGED; PREVALENCE; RENAL INSUFFICIENCY, CHRONIC; RISK FACTORS; YOUNG ADULT;

EID: 84907196489     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013060591     Document Type: Article

References (35)

1. National Kidney Foundation: K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 39[Suppl 1]: S1-S266, 2002
2. Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, Rossert J, De Zeeuw D, Hostetter TH, Lameire N, Eknoyan G: Definition and classification of chronic kidney disease: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int 67: 2089-2100, 2005
3. Levey AS, Atkins R, Coresh J, Cohen EP, Collins AJ, Eckardt KU, Nahas ME, Jaber BL, Jadoul M, Levin A, Powe NR, Rossert J, Wheeler DC, Lameire N, Eknoyan G: Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from Kidney Disease Improving Global Outcomes. Kidney Int 72: 247-259, 2007
4. Zhang QL, Rothenbacher D: Prevalence of chronic kidney disease in population-based studies: Systematic review. BMC Public Health 8: 117, 2008
5. Zoccali C, Kramer A, Jager KJ: Epidemiology of CKD in Europe: An uncertain scenario. Nephrol Dial Transplant 25: 1731-1733, 2010
6. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS: Prevalence of chronic kidney disease in the United States. JAMA 298: 2038-2047, 2007
7. HalbesmaN, JansenDF, Stolk RP, De Jong PE, Gansevoort RT; PREVEND Study group: Changes in renal risk factors versus renal function outcome during follow-up in a population-based cohort study. Nephrol Dial Transplant 25: 1846-1853, 2010
8. Hallan SI, Coresh J, Astor BC, Asberg A, Powe NR, Romundstad S, Hallan HA, Lydersen S, Holmen J: International comparison of the relationship of chronic kidney disease prevalence and ESRD risk. J Am Soc Nephrol 17: 2275-2284, 2006
9. Gambaro G, Yabarek T, Graziani MS, Gemelli A, Abaterusso C, Frigo AC, Marchionna N, Citron L, Bonfante L, Grigoletto F, Tata S, Ferraro PM, Legnaro A, Meneghel G, Conz P, Rizzotti P, D'Angelo A, Lupo A; INCIPE StudyGroup: Prevalence of CKD in northeastern Italy: Results of the INCIPE study and comparison with NHANES. Clin J Am Soc Nephrol 5: 1946-1953, 2010
10. Cirillo M, Laurenzi M, Mancini M, Zanchetti A, Lombardi C, De Santo NG: Low glomerular filtration in the population: Prevalence, associated disorders, and awareness. Kidney Int 70: 800-806, 2006
11. Zhang L, Zhang P, Wang F, Zuo L, Zhou Y, Shi Y, Li G, Jiao S, Liu Z, Liang W, Wang H: Prevalence and factors associated with CKD: A population study from Beijing. Am J Kidney Dis 51: 373-384, 2008
12. Zhang L, Wang F, Wang L, WangW, Liu B, Liu J, Chen M, He Q, Liao Y, Yu X, Chen N, Zhang JE, Hu Z, Liu F, Hong D, Ma L, Liu H, Zhou X, Chen J, Pan L, ChenW, WangW, Li X, Wang H: Prevalence of chronic kidney disease in China: A cross-sectional survey. Lancet 379: 815-822, 2012
13. Nugent RA, Fathima SF, Feigl AB, Chyung D: The burden of chronic kidney disease on developing nations: A 21st century challenge in global health. Nephron Clin Pract 118: c269-c277, 2011
14. McCullough K, Sharma P, Ali T, Khan I, SmithWC, MacLeod A, Black C: Measuring the population burden of chronic kidney disease: A systematic literature review of the estimated prevalence of impaired kidney function. Nephrol Dial Transplant 27: 1812-1821, 2012
15. Levey AS, Coresh J: Chronic kidney disease. Lancet 379: 165-180, 2012
16. Böger CA, GorskiM, LiM, HoffmannMM, Huang C, YangQ, Teumer A, Krane V, O'Seaghdha CM, Kutalik Z, Wichmann HE, Haak T, Boes E, Coassin S, Coresh J, Kollerits B, Haun M, Paulweber B, Köttgen A, Li G, Shlipak MG, Powe N, Hwang SJ, Dehghan A, Rivadeneira F, Uitterlinden A, Hofman A, Beckmann JS, Krämer BK, Witteman J, BochudM, Siscovick D, Rettig R, Kronenberg F, Wanner C, Thadhani RI, Heid IM, Fox CS, KaoWH; CKDGen Consortium: Association of eGFRrelated loci identified by GWAS with incident CKD and ESRD. PLoS Genet 7: e1002292, 2011
17. Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, Smith AV, Arking DE, Astor BC, Boerwinkle E, Ehret GB, Ruczinski I, Scharpf RB, Chen YD, de Boer IH, Haritunians T, Lumley T, Sarnak M, Siscovick D, Benjamin EJ, Levy D, Upadhyay A, Aulchenko YS, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, Chasman DI, Paré G, Ridker PM, KaoWH, Witteman JC, Coresh J, Shlipak MG, Fox CS: Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 41: 712-717, 2009
18. Lindeman RD, Tobin J, Shock NW: Longitudinal studies on the rate of decline in renal function with age. J Am Geriatr Soc 33: 278-285, 1985
19. Glassock RJ, Winearls C: An epidemic of CKD: Fact or fiction? NDT 23: 1117-1121, 2008
20. Pilia G, ChenWM, Scuteri A, Orrú M, Albai G, DeiM, Lai S, Usala G, Lai M, Loi P, Mameli C, Vacca L, DeianaM, Olla N, Masala M, Cao A, Najjar SS, Terracciano A, Nedorezov T, Sharov A, Zonderman AB, Abecasis GR, Costa P, Lakatta E, Schlessinger D: Heritability of cardiovascular and personality traits in 6, 148 Sardinians. PLoS Genet 2: e132, 2006
21. Kidney Disease; Improving Global Outcomes (KDIGO) CKD Work Group: KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 3: 1-150, 2013
22. Francalacci P, Morelli L, Angius A, Berutti R, Reinier F, Atzeni R, Pilu R, Busonero F, Maschio A, Zara I, Sanna D, Useli A, Urru MF, Marcelli M, Cusano R, Oppo M, Zoledziewska M, Pitzalis M, Deidda F, Porcu E, Poddie F, Kang HM, Lyons R, Tarrier B, Gresham JB, Li B, Tofanelli S, Alonso S, Dei M, Lai S, Mulas A, Whalen MB, Uzzau S, Jones C, Schlessinger D, Abecasis GR, Sanna S, Sidore C, Cucca F: Low-pass DNAsequencing of 1200 Sardinians reconstructs European Y-chromosome phylogeny. Science 341: 565-569, 2013
23. Meguid El Nahas A, Bello AK: Chronic kidney disease: The global challenge. Lancet 365: 331-340, 2005
24. Skali H, Uno H, Levey AS, Inker LA, PfefferMA, Solomon SD: Prognostic assessment of estimated glomerular filtration rate by the new Chronic Kidney Disease Epidemiology Collaboration equation in comparison with the Modification of Diet in Renal Disease Study equation. Am Heart J 162: 548-554, 2011
25. van den Brand JA, van Boekel GA, Willems HL, Kiemeney LA, den HeijerM, Wetzels JF: Introduction of the CKD-EPI equation to estimate glomerular filtration rate in a Caucasian population. Nephrol Dial Transplant 26: 3176-3181, 2011
26. Delanaye P, Cavalier E, Mariat C, Maillard N, Krzesinski JM: MDRD or CKD-EPI study equations for estimating prevalence of stage 3 CKD in epidemiological studies: Which difference? Is this difference relevant? BMC Nephrol 11: 8, 2010
27. Glassock RJ, Winearls C: Ageing and the glomerular filtration rate: Truths and consequences. Trans AmClin Climatol Assoc 120: 419-428, 2009
28. Zoccali C, Kramer A, Jager KJ: Chronic kidney disease and end-stage renal disease - a reviewproduced to contribute to the report 'the status of health in the European union: towards a healthier Europe'. NDT Plus 3: 213-224, 2010
29. Fliser D: Ren sanus in corpore sano: The myth of the inexorable decline of renal function with senescence. Nephrol Dial Transplant 20: 482-485, 2005
30. Eurostat. European Health Interview Survey. Between 8% and 25% of adults are obese across member states. No systematic differences between women and men. News release. November 24, 2011
31. Rule AD, Glassock RJ: GFR estimating equations: Getting closer to the truth? Clin J Am Soc Nephrol 8: 1414-1420, 2013
32. Köttgen A, Yang Q, Shimmin LC, Tin A, Schaeffer C, Coresh J, Liu X, Rampoldi L, Hwang SJ, Boerwinkle E, Hixson JE, Kao WH, Fox CS, Boerwinkle E, Ehret GB, Ruczinski I, Scharpf RB, Chen YD, de Boer IH, Haritunians T, Lumley T, Sarnak M, Siscovick D, Benjamin EJ, Levy D, Upadhyay A, Aulchenko YS, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, Chasman DI, Paré G, Ridker PM, KaoWH, Witteman JC, Coresh J, Shlipak MG, Fox CS: Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing. PLoS ONE 7: e38311, 2012
33. Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, LiM, O'Connell JR, Tanaka T, Peralta CA, Kutalik Z, Luan J, Zhao JH, Hwang SJ, Akylbekova E, Kramer H, van der Harst P, Smith AV, Lohman K, de Andrade M, Hayward C, Kollerits B, Tönjes A, Aspelund T, Ingelsson E, Eiriksdottir G, Launer LJ, Harris TB, Shuldiner AR, Mitchell BD, Arking DE, Franceschini N, Boerwinkle E, Egan J, Hernandez D, ReillyM, Townsend RR, Lumley T, Siscovick DS, Psaty BM, Kestenbaum B, Haritunians T, Bergmann S, Vollenweider P, Waeber G, Mooser V, Waterworth D, Johnson AD, Florez JC, Meigs JB, Lu X, Turner ST, Atkinson EJ, Leak TS, Aasarød K, Skorpen F, Syvänen AC, Illig T, Baumert J, Koenig W, Krämer BK, Devuyst O, Mychaleckyj JC, Minelli C, Bakker SJ, Kedenko L, Paulweber B, Coassin S, Endlich K, Kroemer HK, Biffar R, Stracke S, Völzke H, StumvollM, Mägi R, Campbell H, Vitart V, Hastie ND, Gudnason V, Kardia SL, Liu Y, Polasek O, Curhan G, Kronenberg F, Prokopenko I, Rudan I, Arnlöv J, Hallan S, Navis G, Parsa A, Ferrucci L, Coresh J, Shlipak MG, Bull SB, Paterson NJ, Wichmann HE, Wareham NJ, Loos RJ, Rotter JI, Pramstaller PP, Cupples LA, Beckmann JS, Yang Q, Heid IM, Rettig R, Dreisbach AW, Bochud M, Fox CS, Kao WH; CKDGen Consortium: CUBN is a gene locus for albuminuria. J Am Soc Nephrol 22: 555-570, 2011
34. Selvin E, Manzi J, Stevens LA, Van Lente F, Lacher DA, Levey AS, Coresh J: Calibration of serum creatinine in the National Health and Nutrition Examination Surveys (NHANES) 1988-1994, 1999-2004.AmJ Kidney Dis 50: 918-926, 2007
35. Hallan S, Astor B, Lydersen S: Estimating glomerular filtration rate in the general population: the second Health Survey of Nord- Trondelag (HUNT II). Nephrol Dial Transplant 21: 1525-1533, 2006