TLR-Mediated inflammatory responses to streptococcus pneumoniae are highly dependent on surface expression of bacterial lipoproteins

Journal of Immunology

Volumn 193, Issue 7, 2014, Pages 3736-3745

  Tomlinson, Gillian ^a   Chimalapati, Suneeta ^a   Pollard, Tracey ^a   Lapp, Thabo ^a,g   Cohen, Jonathan ^a,b   Camberlein, Emilie ^a,h   Stafford, Sian ^a   Periselneris, Jimstan ^a   Aldridge, Christine ^c   Vollmer, Waldemar ^c   Picard, Capucine ^d,e   Casanova, Jean Laurent ^d,f   Noursadeghi, Mahdad ^a   Brown, Jeremy ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d IMAGINE INSTITUTE   (France)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

^f ROCKEFELLER UNIVERSITY   (United States)

^g UNIVERSITY OF FREIBURG   (Germany)

^h UNIVERSITÉ DE NANTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; LIPOPROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK4 PROTEIN, HUMAN; IRAK4 PROTEIN, MOUSE; TLR2 PROTEIN, HUMAN; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; FEMALE; GENE; GENE MUTATION; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE; LIPOPROTEIN DIACYLGLYCERYL TRANSFERASE GENE; MACROPHAGE; MOUSE; NONHUMAN; PNEUMONIA; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; TRANSCRIPTOMICS; ANIMAL; CLINICAL TRIAL; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; IMMUNE DEFICIENCY; IMMUNOLOGY; KNOCKOUT MOUSE; MALE; PATHOLOGY; STREPTOCOCCUS PNEUMONIA;

ANIMALS; BACTERIAL PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; HEK293 CELLS; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPROTEINS; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; NF-KAPPA B; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907195503     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401413     Document Type: Article

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