DGKI methylation status modulates the prognostic value of MGMT in glioblastoma patients treated with combined radio-chemotherapy with temozolomide

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Etcheverry, Amandine ^a,b,d   Aubry, Marc ^c,k   Idbaih, Ahmed ^e,l   Vauleon, Elodie ^a,b,f   Marie, Yannick ^e   Menei, Philippe ^g   Boniface, Rachel ^a,b   Figarella Branger, Dominique ^h,i   Karayan Tapon, Lucie ^c,j,k   Quillien, Veronique ^a,b,f   Sanson, Marc ^e,l   De Tayrac, Marie ^a,b,d   Delattre, Jean Yves ^e,l   Mosser, Jean ^a,b,c,d  

^a UNIVERSITÉ DE RENNES 1   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c Plate forme Génomique Santé Biogenouest Biosit ^*  (France)

^d RENNES UNIVERSITY HOSPITAL   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^f CENTRE EUGÈNE MARQUIS   (France)

^g ANGERS UNIVERSITY HOSPITAL   (France)

^h TIMONE HOSPITAL   (France)

ⁱ University of the Mediterranean Aix Marseille II   (France)

^j UNIVERSITÉ DE POITIERS   (France)

^k POITIERS UNIVERSITY HOSPITAL   (France)

^l INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE IOTA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; TEMOZOLOMIDE; UNCLASSIFIED DRUG; ALKYLATING AGENT; DACARBAZINE; DNA METHYLTRANSFERASE; IDH1 PROTEIN, HUMAN; ISOCITRATE DEHYDROGENASE; MGMT PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TUMOR SUPPRESSOR PROTEIN;

ADJUVANT THERAPY; ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER PATIENT; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER SURVIVAL; CHEMORADIOTHERAPY; COHORT ANALYSIS; CONTROLLED STUDY; DGKI GENE; DNA DETERMINATION; DNA METHYLATION; FEMALE; GENE IDENTIFICATION; GLIOBLASTOMA; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MALE; MGMT GENE; NOMOGRAM; POPULATION GENETICS; POPULATION RESEARCH; PREDICTIVE VALUE; PROMOTER REGION; RETROSPECTIVE STUDY; TREATMENT RESPONSE; ANALOGS AND DERIVATIVES; CLINICAL TRIAL; DISEASE FREE SURVIVAL; GENETICS; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS, ALKYLATING; CHEMORADIOTHERAPY; COHORT STUDIES; DACARBAZINE; DIACYLGLYCEROL KINASE; DISEASE-FREE SURVIVAL; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; FEMALE; GLIOBLASTOMA; HUMANS; ISOCITRATE DEHYDROGENASE; MALE; MIDDLE AGED; NOMOGRAMS; PROGNOSIS; PROMOTER REGIONS, GENETIC; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; TUMOR SUPPRESSOR PROTEINS; YOUNG ADULT;

EID: 84907192005     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0104455     Document Type: Article

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