-
1
-
-
0032076542
-
Jak2 is essential for signaling through a variety of cytokine receptors
-
Parganas E, Wang D, Stravopodis D, Topham DJ, Marine JC, Teglund S, et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell 1998; 93: 385-95.
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
Wang, D.2
Stravopodis, D.3
Topham, D.J.4
Marine, J.C.5
Teglund, S.6
-
2
-
-
2942587457
-
Impaired alveologenesis and maintenance of secretory mammary epithelial cells in jak2 conditional knockout mice
-
Wagner KU, Krempler A, Triplett AA, Qi Y, George NM, Zhu J, et al. Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice. Mol Cell Biol 2004; 24: 5510-20.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5510-5520
-
-
Wagner, K.U.1
Krempler, A.2
Triplett, A.A.3
Qi, Y.4
George, N.M.5
Zhu, J.6
-
3
-
-
79959956046
-
The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors
-
Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker SR, et al. The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors. J Clin Invest 2011; 121: 2723-35.
-
(2011)
J Clin Invest
, vol.121
, pp. 2723-2735
-
-
Marotta, L.L.1
Almendro, V.2
Marusyk, A.3
Shipitsin, M.4
Schemme, J.5
Walker, S.R.6
-
4
-
-
84878552107
-
Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8
-
Hartman ZC, Poage GM, den Hollander P, Tsimelzon A, Hill J, Panupinthu N, et al. Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8. Cancer Res 2013; 73: 3470-80.
-
(2013)
Cancer Res
, vol.73
, pp. 3470-3480
-
-
Hartman, Z.C.1
Poage, G.M.2
Den Hollander, P.3
Tsimelzon, A.4
Hill, J.5
Panupinthu, N.6
-
5
-
-
84870825008
-
JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: A rationale for cotargeting these pathways in metastatic breast cancer
-
Britschgi A, Andraos R, Brinkhaus H, Klebba I, Romanet V, Muller U, et al. JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer. Cancer Cell 2012; 22: 796-811.
-
(2012)
Cancer Cell
, vol.22
, pp. 796-811
-
-
Britschgi, A.1
Andraos, R.2
Brinkhaus, H.3
Klebba, I.4
Romanet, V.5
Muller, U.6
-
7
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011; 121: 2750-67.
-
(2011)
J Clin Invest
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
Sanders, M.E.4
Chakravarthy, A.B.5
Shyr, Y.6
-
8
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, et al. Molecular portraits of human breast tumours. Nature 2000; 406: 747-52.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
Van De Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
-
9
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001; 98: 10869-74.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
-
10
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
Paik S, Shak S, Tang G, Kim C, Baker J, Cronin M, et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 2004; 351: 2817-26.
-
(2004)
N Engl J Med
, vol.351
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
Kim, C.4
Baker, J.5
Cronin, M.6
-
11
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, Voskuil DW, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002; 347: 1999-2009.
-
(2002)
N Engl J Med
, vol.347
, pp. 1999-2009
-
-
Van De Vijver, M.J.1
He, Y.D.2
Van'T Veer, L.J.3
Dai, H.4
Hart, A.A.5
Voskuil, D.W.6
-
12
-
-
84877737214
-
Development of a prognostic model for breast cancer survival in an open challenge environment
-
Cheng WY, Ou Yang TH, Anastassiou D. Development of a prognostic model for breast cancer survival in an open challenge environment. Sci Transl Med 2013; 5: 181ra50.
-
(2013)
Sci Transl Med
, vol.5
-
-
Cheng, W.Y.1
Ou Yang, T.H.2
Anastassiou, D.3
-
14
-
-
84861527388
-
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
-
Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 2012; 486: 346-52.
-
(2012)
Nature
, vol.486
, pp. 346-352
-
-
Curtis, C.1
Shah, S.P.2
Chin, S.F.3
Turashvili, G.4
Rueda, O.M.5
Dunning, M.J.6
-
15
-
-
84878228719
-
Prognostic models: Rising to the challenge
-
McCarthy N. Prognostic models: rising to the challenge. Nat Rev Cancer 2013; 13: 378.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 378
-
-
McCarthy, N.1
-
16
-
-
33749655549
-
Optimal full matching and related designs via network flows
-
Hansen BB, Klopfer SO. Optimal full matching and related designs via network flows. J Comput Graphical Stat 2006; 15: 609-27.
-
(2006)
J Comput Graphical Stat
, vol.15
, pp. 609-627
-
-
Hansen, B.B.1
Klopfer, S.O.2
-
17
-
-
84871876293
-
R: A language and environment for statistical computing
-
Team RDC. R: a language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2012. ISBN 3-900051-07-0. Available from: http://www.R-project.org/.
-
(2012)
Vienna, Austria: R Foundation for Statistical Computing;
-
-
-
18
-
-
29844444766
-
The R package geepack for generalized estimating equations
-
Halekoh U. Højsgaard S, Yan J. The R package geepack for generalized estimating equations. J Stat Softw 2006; 15: 1-11.
-
(2006)
J Stat Softw
, vol.15
, pp. 1-11
-
-
Halekoh, U.1
Højsgaard, S.2
Yan, J.3
-
20
-
-
70349313947
-
Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial
-
Miller CP, Lowe KA, Valliant-Saunders K, Kaiser JF, Mattern D, Urban N, et al. Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial. Stem Cells 2009; 27: 2353-61.
-
(2009)
Stem Cells
, vol.27
, pp. 2353-2361
-
-
Miller, C.P.1
Lowe, K.A.2
Valliant-Saunders, K.3
Kaiser, J.F.4
Mattern, D.5
Urban, N.6
-
21
-
-
0031039426
-
A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses
-
Kohlhuber F, Rogers NC, Watling D, Feng J, Guschin D, Briscoe J, et al. A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses. Mol Cell Biol 1997; 17: 695-706.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 695-706
-
-
Kohlhuber, F.1
Rogers, N.C.2
Watling, D.3
Feng, J.4
Guschin, D.5
Briscoe, J.6
-
23
-
-
85043550937
-
-
arXiv:2013;1306.2584v2
-
Cheng W, Ou Yang TH, Shen H, Laird PW, Anastassiou D, and The Cancer Genome Atlas. Multi-cancer molecular signatures and their interrelationships. arXiv: 2013; 1306.2584v2.
-
The Cancer Genome Atlas. Multi-cancer Molecular Signatures and their Interrelationships
-
-
Cheng, W.1
Ou Yang, T.H.2
Shen, H.3
Laird, P.W.4
Anastassiou, D.5
-
24
-
-
67651151400
-
Metastasis-promoting immunity: When T cells turn to the dark side
-
Pardoll D. Metastasis-promoting immunity: when T cells turn to the dark side. Cancer Cell 2009; 16: 81-2.
-
(2009)
Cancer Cell
, vol.16
, pp. 81-82
-
-
Pardoll, D.1
-
25
-
-
79956138117
-
Quantitative comparison of erythropoietin receptor levels in the epithelial versus endothelial fractions of primary breast tumors
-
Miller CP, Urban N, Blau CA. Quantitative comparison of erythropoietin receptor levels in the epithelial versus endothelial fractions of primary breast tumors. Anticancer Res 2011; 31: 1189-95.
-
(2011)
Anticancer Res
, vol.31
, pp. 1189-1195
-
-
Miller, C.P.1
Urban, N.2
Blau, C.A.3
-
26
-
-
0028910222
-
Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: Differential use of janus family tyrosine kinases by IL-2 and IL-12
-
Bacon CM, McVicar DW, Ortaldo JR, Rees RC, O'Shea JJ, Johnston JA. Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12. J Exp Med 1995; 181: 399-404.
-
(1995)
J Exp Med
, vol.181
, pp. 399-404
-
-
Bacon, C.M.1
McVicar, D.W.2
Ortaldo, J.R.3
Rees, R.C.4
O'Shea, J.J.5
Johnston, J.A.6
-
27
-
-
0027914818
-
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway
-
Watling D, Guschin D, Muller M, Silvennoinen O, Witthuhn BA, Quelle FW, et al. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway. Nature 1993; 366: 166-70.
-
(1993)
Nature
, vol.366
, pp. 166-170
-
-
Watling, D.1
Guschin, D.2
Muller, M.3
Silvennoinen, O.4
Witthuhn, B.A.5
Quelle, F.W.6
-
28
-
-
77954531991
-
Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: Preclinical characterization of INCB028050
-
Fridman JS, Scherle PA, Collins R, Burn TC, Li Y, Li J, et al. Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050. J Immunol 2010; 184: 5298-307.
-
(2010)
J Immunol
, vol.184
, pp. 5298-5307
-
-
Fridman, J.S.1
Scherle, P.A.2
Collins, R.3
Burn, T.C.4
Li, Y.5
Li, J.6
-
29
-
-
84868606215
-
IFNγR signaling mediates alloreactive T-cell trafficking and GVHD
-
Choi J, Ziga ED, Ritchey J, Collins L, Prior JL, Cooper ML, et al. IFNγR signaling mediates alloreactive T-cell trafficking and GVHD. Blood 2012; 120: 4093-103.
-
(2012)
Blood
, vol.120
, pp. 4093-4103
-
-
Choi, J.1
Ziga, E.D.2
Ritchey, J.3
Collins, L.4
Prior, J.L.5
Cooper, M.L.6
|