Plasma concentrations of afamin are associated with the prevalence and development of metabolic syndrome

Circulation: Cardiovascular Genetics

Volumn 7, Issue 6, 2014, Pages 822-829

  Kronenberg, Florian ^a   Kollerits, Barbara ^a   Kiechl, Stefan ^a   Lamina, Claudia ^a   Kedenko, Lyudmyla ^b   Meisinger, Christa ^c,d   Willeit, Johann ^a   Huth, Cornelia ^c,d   Wietzorrek, Georg ^a   Altmann, Maria E ^e   Thorand, Barbara ^c,d   Melmer, Andreas ^a   Dähnhardt, Doreen ^a   Santer, Peter ^f   Rathmann, Wolfgang ^g   Paulweber, Bernhard ^b   Koenig, Wolfgang ^h   Peters, Annette ^c,d   Adham, Ibrahim M ^e   Dieplinger, Hans ^a,i  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b PARACELSUS MEDICAL UNIVERSITY   (Austria)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^e UNIVERSITY OF GÖTTINGEN   (Germany)

^f BRUNECK HOSPITAL   (Italy)

^g HEINRICH HEINE UNIVERSITY   (Germany)

^h UNIVERSITY HOSPITAL ULM   (Germany)

ⁱ Vitateq   (Austria)

Author keywords

Afamin protein; Epidemiology; Glucose; Human; Lipoproteins; Metabolic syndrome X; Metabolism; Obesity

Indexed keywords

AFAMIN; GLUCOSE; GLYCOPROTEIN; LIPID; UNCLASSIFIED DRUG; AFM PROTEIN, HUMAN; CARRIER PROTEIN; GLUCOSE BLOOD LEVEL; SERUM ALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; GENE OVEREXPRESSION; GLUCOSE BLOOD LEVEL; HUMAN; LIPID BLOOD LEVEL; METABOLIC SYNDROME X; MOUSE; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; TRANSGENIC MOUSE; WAIST CIRCUMFERENCE; ADULT; AGED; ANALYSIS; ANIMAL; BLOOD; FACTUAL DATABASE; FEMALE; FOLLOW UP; MALE; META ANALYSIS; MIDDLE AGED; PATHOLOGY; PHENOTYPE; RISK; STATISTICAL MODEL;

MUS MUSCULUS;

ADULT; AGED; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CARRIER PROTEINS; DATABASES, FACTUAL; FEMALE; FOLLOW-UP STUDIES; GLYCOPROTEINS; HUMANS; LOGISTIC MODELS; MALE; METABOLIC SYNDROME X; MICE; MICE, TRANSGENIC; MIDDLE AGED; ODDS RATIO; PHENOTYPE; PREVALENCE; SERUM ALBUMIN;

EID: 84907059816     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.113.000654     Document Type: Article

References (22)

1. Lichenstein HS, Lyons DE, Wurfel MM, Johnson DA, McGinley MD, Leidli JC, et al. Afamin is a new member of the albumin, a-fetoprotein, and vitamin D-binding protein gene family. J Biol Chem. 1994;269:18149-18154
2. Araki T, Haupt H, Hermentin P, Schwick HG, Kimura Y, Schmid K, et al. Preparation and partial structural characterization of alpha1T-glycoprotein from normal human plasma. Arch Biochem Biophys. 1998;351:250-256
3. Bélanger L, Roy S, Allard D. New albumin gene 3' adjacent to the alpha 1-fetoprotein locus. J Biol Chem. 1994;269:5481-5484
4. Jerkovic L, Voegele AF, Chwatal S, Kronenberg F, Radcliffe CM, Wormald MR, et al. Afamin is a novel human vitamin e-binding glycoprotein characterization and in vitro expression. J Proteome Res. 2005;4:889-899
5. Voegele AF, Jerkovi L, Wellenzohn B, Eller P, Kronenberg F, Liedl KR, et al. Characterization of the vitamin E-binding properties of human plasma afamin. Biochemistry. 2002;41:14532-14538
6. Taketo M, Schroeder AC, Mobraaten LE, Gunning KB, Hanten G, Fox RR, et al. Fvb/n: an inbred mouse strain preferable for transgenic analyses. Proc Natl Acad Sci U S A. 1991;88:2065-2069
7. Pinkert CA, Ornitz DM, Brinster RL, Palmiter RD. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev. 1987;1:268-276
8. Kronenberg F, Kronenberg MF, Kiechl S, Trenkwalder E, Santer P, Oberhollenzer F, Egger G, et al. Role of lipoprotein(a) and apolipoprotein(a) phenotype in atherogenesis: prospective results from the Bruneck study. Circulation. 1999;100:1154-1160
9. Tsimikas S, Kiechl S, Willeit J, Mayr M, Miller ER, Kronenberg F, Xu Q, et al. Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study. J Am Coll Cardiol. 2006;47:2219-2228
10. Heid IM, Wagner SA, Gohlke H, Iglseder B, Mueller JC, Cip P, Ladurner G, et al. Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians. Diabetes. 2006;55:375-384
11. Löwel H, Döring A, Schneider A, Heier M, Thorand B, Meisinger C; MONICA/ KORA Study Group. The MONICA Augsburg surveys-basis for prospective cohort studies. Gesundheitswesen. 2005;67(suppl 1):S13-S18
12. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112:2735-2752
13. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640-1645
14. Dieplinger B, Egger M, Gabriel C, Poelz W, Morandell E, Seeber B, et al. Analytical characterization and clinical evaluation of an enzyme-linked immunosorbent assay for measurement of afamin in human plasma. Clin Chim Acta. 2013;425:236-241
15. Tall A. Plasma lipid transfer proteins. Annu Rev Biochem. 1995;64:235-257
16. Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes. 2007;56:1010-1013
17. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006;116:1793-1801
18. Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, et al. The nlrp3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med. 2011;17:179-188
19. Duncan BB, Schmidt MI, Pankow JS, Ballantyne CM, Couper D, Vigo A, et al. Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes. 2003;52:1799-1805
20. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA. 2001;286:327-334
21. Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, Tataranni PA. High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes. Diabetes. 2002;51:455-461
22. de Rekeneire N, Peila R, Ding J, Colbert LH, Visser M, Shorr RI, et al. Diabetes, hyperglycemia, and inflammation in older individuals: The health, aging and body composition study. Diabetes Care. 2006;29:1902-1908.