-
1
-
-
80054800194
-
Common cellular and molecular mechanisms in obesity and drug addiction
-
Kenny PJ. Common cellular and molecular mechanisms in obesity and drug addiction. Nat Rev Neurosci. 2011;12:638-651.
-
(2011)
Nat Rev Neurosci.
, vol.12
, pp. 638-651
-
-
Kenny, P.J.1
-
2
-
-
67649970990
-
Processing of peptide and hormone precursors at the dibasic cleavage sites
-
Rholam M, Fahy C. Processing of peptide and hormone precursors at the dibasic cleavage sites. Cell Mol Life Sci. 2009;66:2075-2091.
-
(2009)
Cell Mol Life Sci.
, vol.66
, pp. 2075-2091
-
-
Rholam, M.1
Fahy, C.2
-
3
-
-
77953311302
-
Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative pep-tidomics
-
Wardman JH, Zhang X, Gagnon S, et al. Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative pep-tidomics. J Neurochem. 2010;114:215-225.
-
(2010)
J Neurochem.
, vol.114
, pp. 215-225
-
-
Wardman, J.H.1
Zhang, X.2
Gagnon, S.3
-
4
-
-
84856523505
-
Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity
-
Creemers JW, Choquet H, Stijnen P, et al. Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity. Diabetes. 2012;61:383-390.
-
(2012)
Diabetes.
, vol.61
, pp. 383-390
-
-
Creemers, J.W.1
Choquet, H.2
Stijnen, P.3
-
5
-
-
48349113289
-
Common nonsynony-mous variants in PCSK1 confer risk of obesity
-
Benzinou M, Creemers JW, Choquet H, et al. Common nonsynony-mous variants in PCSK1 confer risk of obesity. Nat Genet. 2008; 40:943-945.
-
(2008)
Nat Genet.
, vol.40
, pp. 943-945
-
-
Benzinou, M.1
Creemers, J.W.2
Choquet, H.3
-
6
-
-
80052829855
-
The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status
-
Gjesing AP, Vestmar MA, Jorgensen T, et al. The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status. PLoS One. 2011;6:e23907.
-
(2011)
PLoS One.
, vol.6
, pp. e23907
-
-
Gjesing, A.P.1
Vestmar, M.A.2
Jorgensen, T.3
-
7
-
-
33744763342
-
Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice
-
Lloyd DJ, Bohan S, Gekakis N. Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice. Hum Mol Genet. 2006; 15:1884-1893.
-
(2006)
Hum Mol Genet.
, vol.15
, pp. 1884-1893
-
-
Lloyd, D.J.1
Bohan, S.2
Gekakis, N.3
-
8
-
-
84886531614
-
From diarrhea to obesity in prohormone convertase 1/3 deficiency: Age-dependent clinical, pathologic, and enteroendocrine characteristics
-
Bandsma RH, Sokollik C, Chami R, et al. From diarrhea to obesity in prohormone convertase 1/3 deficiency: age-dependent clinical, pathologic, and enteroendocrine characteristics. J Clin Gastroen-terol. 2013;47:834-843.
-
(2013)
J Clin Gastroen-terol.
, vol.47
, pp. 834-843
-
-
Bandsma, R.H.1
Sokollik, C.2
Chami, R.3
-
9
-
-
84879480364
-
Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathiesin apediatric cohort
-
Martin MG, Lindberg I, Solorzano-Vargas RS, et al. Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathiesin apediatric cohort. Gastroenterology. 2013;145:138-148.
-
(2013)
Gastroenterology.
, vol.145
, pp. 138-148
-
-
Martin, M.G.1
Lindberg, I.2
Solorzano-Vargas, R.S.3
-
10
-
-
84866331827
-
Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3
-
Dillon SL, Williamson DM, Elferich J, et al. Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3. J Mol Biol. 2012;423:47-62.
-
(2012)
J Mol Biol.
, vol.423
, pp. 47-62
-
-
Dillon, S.L.1
Williamson, D.M.2
Elferich, J.3
-
11
-
-
0028801027
-
Ionic milieu controls the compartment-specific activation of pro-opiomelanocortin processing in AtT-20 cells
-
Schmidt WK, Moore H-PH. Ionic milieu controls the compartment-specific activation of pro-opiomelanocortin processing in AtT-20 cells. Mol Biol Cell. 1995;6:1271-1285.
-
(1995)
Mol Biol Cell.
, vol.6
, pp. 1271-1285
-
-
Schmidt, W.K.1
Moore, H.-P.H.2
-
12
-
-
0028238009
-
Evidence for cleavageofthe PC1/PC3 pro-segmentinthe endoplasmic reticulum
-
Lindberg I. Evidence for cleavageofthe PC1/PC3 pro-segmentinthe endoplasmic reticulum. Mol Cell Neurosci. 1994;5:263-268.
-
(1994)
Mol Cell Neurosci.
, vol.5
, pp. 263-268
-
-
Lindberg, I.1
-
13
-
-
0028276806
-
Endoproteolytic processing of proopiomelano-cortin and prohormone convertases 1 and 2 in neuroendocrine cells overexpressing prohormone convertases 1 or 2
-
Zhou A, Mains RE. Endoproteolytic processing of proopiomelano-cortin and prohormone convertases 1 and 2 in neuroendocrine cells overexpressing prohormone convertases 1 or 2. J Biol Chem. 1994; 269:17440-17447.
-
(1994)
J Biol Chem.
, vol.269
, pp. 17440-17447
-
-
Zhou, A.1
Mains, R.E.2
-
14
-
-
0028337442
-
Enzymatic properties of carboxyl-terminally truncated prohormone convertase 1 (PC1/SPC3) and evidence for autocatalytic conversion
-
Zhou Y, Lindberg I. Enzymatic properties of carboxyl-terminally truncated prohormone convertase 1 (PC1/SPC3) and evidence for autocatalytic conversion. J Biol Chem. 1994;269:18408-18413.
-
(1994)
J Biol Chem.
, vol.269
, pp. 18408-18413
-
-
Zhou, Y.1
Lindberg, I.2
-
15
-
-
0028808102
-
Mutational analysis of PC1 (SPC3) in PC12 cells. 66-kDa PC1 is fully functional
-
Zhou Y, Rovere C, Kitabgi P, Lindberg I. Mutational analysis of PC1 (SPC3) in PC12 cells. 66-kDa PC1 is fully functional. J Biol Chem. 1995;270:24702-24706.
-
(1995)
J Biol Chem.
, vol.270
, pp. 24702-24706
-
-
Zhou, Y.1
Rovere, C.2
Kitabgi, P.3
Lindberg, I.4
-
16
-
-
0025803098
-
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2 Furin and Kex2: Distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2
-
Seidah NG, Marcinkiewicz M, Benjannet S, et al. Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2. Mol Endocrinol. 1991;5:111-122.
-
(1991)
Mol Endocrinol.
, vol.5
, pp. 111-122
-
-
Seidah, N.G.1
Marcinkiewicz, M.2
Benjannet, S.3
-
17
-
-
0026725984
-
The cDNA sequence of the human pro-hormone and pro-protein convertase PC1
-
Seidah NG, Hamelin J, Gaspar AM, Day R, Chretien M. The cDNA sequence of the human pro-hormone and pro-protein convertase PC1. DNA Cell Biol. 1992;11:283-289.
-
(1992)
DNA Cell Biol.
, vol.11
, pp. 283-289
-
-
Seidah, N.G.1
Hamelin, J.2
Gaspar, A.M.3
Day, R.4
Chretien, M.5
-
19
-
-
0026503049
-
Expression in human lung tumor cells of the proprotein processing enzyme PC1/PC3. Cloning and primary sequence of a 5 kb cDNA
-
Creemers JW, Roebroek AJ, Van de Ven WJ. Expression in human lung tumor cells of the proprotein processing enzyme PC1/PC3. Cloning and primary sequence of a 5 kb cDNA. FEBS Lett. 1992; 300:82-88.
-
(1992)
FEBS Lett.
, vol.300
, pp. 82-88
-
-
Creemers, J.W.1
Roebroek, A.J.2
Van De Ven, W.J.3
-
20
-
-
84873801109
-
Functional consequences of a novel variant of PCSK1
-
Pickett LA, Yourshaw M, Albornoz V, et al. Functional consequences of a novel variant of PCSK1. PLoS One. 2013;8:e55065.
-
(2013)
PLoS One.
, vol.8
, pp. e55065
-
-
Pickett, L.A.1
Yourshaw, M.2
Albornoz, V.3
-
22
-
-
0030949271
-
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
-
Jackson RS, Creemers JW, Ohagi S, et al. Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Nat Genet. 1997;16:303-306.
-
(1997)
Nat Genet.
, vol.16
, pp. 303-306
-
-
Jackson, R.S.1
Creemers, J.W.2
Ohagi, S.3
-
23
-
-
0346096721
-
Small-intestinal dysfunction accompanies the complex endocrinopathy of human pro-protein convertase 1 deficiency
-
Jackson RS, Creemers JW, Farooqi IS, et al. Small-intestinal dysfunction accompanies the complex endocrinopathy of human pro-protein convertase 1 deficiency. J Clin Invest. 2003;112:1550-1560.
-
(2003)
J Clin Invest.
, vol.112
, pp. 1550-1560
-
-
Jackson, R.S.1
Creemers, J.W.2
Farooqi, I.S.3
-
24
-
-
34548765134
-
Hyperphagia and early-onset obesity due to a novel homozygous missense mutation in prohormone convertase 1/3
-
Farooqi IS, Volders K, Stanhope R, et al. Hyperphagia and early-onset obesity due to a novel homozygous missense mutation in prohormone convertase 1/3. J Clin Endocrinol Metab. 2007;92:3369-3373.
-
(2007)
J Clin Endocrinol Metab.
, vol.92
, pp. 3369-3373
-
-
Farooqi, I.S.1
Volders, K.2
Stanhope, R.3
-
25
-
-
84922657340
-
A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity [published online June 3, 2014]
-
Philippe J, Stijnen P, Meyre D, et al. A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity [published online June 3, 2014]. Int J Obes (Lond). doi: 10.1038/ijo.2014.96.
-
Int J Obes (Lond).
-
-
Philippe, J.1
Stijnen, P.2
Meyre, D.3
-
26
-
-
84875115035
-
Anamphipathic a-he-lix in the prodomain of cocaine and amphetamine regulated transcript peptide precursor serves as its sorting signal to the regulated secretory pathway
-
Blanco EH, Lagos CF, Andres ME, Gysling K. Anamphipathic a-he-lix in the prodomain of cocaine and amphetamine regulated transcript peptide precursor serves as its sorting signal to the regulated secretory pathway. PLoS One. 2013;8:e59695.
-
(2013)
PLoS One.
, vol.8
, pp. e59695
-
-
Blanco, E.H.1
Lagos, C.F.2
Andres, M.E.3
Gysling, K.4
-
27
-
-
0026772528
-
Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells
-
Vindrola O, Lindberg I. Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells. Mol Endocrinol. 1992;6:1088-1094.
-
(1992)
Mol Endocrinol.
, vol.6
, pp. 1088-1094
-
-
Vindrola, O.1
Lindberg, I.2
-
28
-
-
0027436437
-
Biosynthesis of the prohormone convertase PC2 in Chinese hamster ovary cells and in rat insulinoma cells
-
Shen FS, Seidah NG, Lindberg I. Biosynthesis of the prohormone convertase PC2 in Chinese hamster ovary cells and in rat insulinoma cells. J Biol Chem. 1993;268:24910-24915.
-
(1993)
J Biol Chem.
, vol.268
, pp. 24910-24915
-
-
Shen, F.S.1
Seidah, N.G.2
Lindberg, I.3
-
29
-
-
0034671486
-
Processing and sorting of the prohormone convertase 2 propeptide
-
Muller L, Cameron A, Fortenberry Y, Apletalina EV, Lindberg I. Processing and sorting of the prohormone convertase 2 propeptide. J Biol Chem. 2000;275:39213-39222.
-
(2000)
J Biol Chem.
, vol.275
, pp. 39213-39222
-
-
Muller, L.1
Cameron, A.2
Fortenberry, Y.3
Apletalina, E.V.4
Lindberg, I.5
-
30
-
-
82755171853
-
Dynamic modulation of PC2-mediated precursor processing by 7B2: Preferential effect on glucagon synthesis
-
Helwig M, Lee SN, Hwang JR, Ozawa A, Medrano JF, Lindberg I. Dynamic modulation of PC2-mediated precursor processing by 7B2: preferential effect on glucagon synthesis. J Biol Chem. 2011; 286:42504-42513.
-
(2011)
J Biol Chem.
, vol.286
, pp. 42504-42513
-
-
Helwig, M.1
Lee, S.N.2
Hwang, J.R.3
Ozawa, A.4
Medrano, J.F.5
Lindberg, I.6
-
32
-
-
34547383713
-
Preparation of iodine-131 labelled human growth hormone of high specific activity
-
Hunter WM, Greenwood FC. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature. 1962;194: 495-496.
-
(1962)
Nature.
, vol.194
, pp. 495-496
-
-
Hunter, W.M.1
Greenwood, F.C.2
-
33
-
-
9644281041
-
Proprotein convertase models based on the crystal structures of furin and kexin: Explanation of their specificity
-
Henrich S, Lindberg I, Bode W, Than ME. Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity. J Mol Biol. 2005;345:211-227.
-
(2005)
J Mol Biol.
, vol.345
, pp. 211-227
-
-
Henrich, S.1
Lindberg, I.2
Bode, W.3
Than, M.E.4
-
34
-
-
0037743535
-
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity
-
Henrich S, Cameron A, Bourenkov GP, et al. The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nat Struct Biol. 2003;10:520-526.
-
(2003)
Nat Struct Biol.
, vol.10
, pp. 520-526
-
-
Henrich, S.1
Cameron, A.2
Bourenkov, G.P.3
-
35
-
-
0032500530
-
Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library
-
Apletalina E, Appel J, Lamango NS, Houghten RA, Lindberg I. Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library. J Biol Chem. 1998;273:26589-26595.
-
(1998)
J Biol Chem.
, vol.273
, pp. 26589-26595
-
-
Apletalina, E.1
Appel, J.2
Lamango, N.S.3
Houghten, R.A.4
Lindberg, I.5
-
36
-
-
0038013621
-
Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1/3
-
Dey A, Xhu X, Carroll R, Turck CW, Stein J, Steiner DF. Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1/3. J Biol Chem. 2003;278:15007-15014.
-
(2003)
J Biol Chem.
, vol.278
, pp. 15007-15014
-
-
Dey, A.1
Xhu, X.2
Carroll, R.3
Turck, C.W.4
Stein, J.5
Steiner, D.F.6
-
37
-
-
0025762119
-
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues
-
Benjannet S, Rondeau N, Day R, Chretien M, Seidah NG. PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues. Proc Natl Acad Sci USA. 1991;88:3564-3568.
-
(1991)
Proc Natl Acad Sci USA.
, vol.88
, pp. 3564-3568
-
-
Benjannet, S.1
Rondeau, N.2
Day, R.3
Chretien, M.4
Seidah, N.G.5
-
38
-
-
82355191718
-
Effects of rs6234/rs6235 and rs6232/rs6234/rs6235 PCSK1 single-nucleotide polymorphism clusters on proprotein convertase 1/3 biosynthesis and activity
-
Mbikay M, Sirois F, Nkongolo KK, Basak A, Chretien M. Effects of rs6234/rs6235 and rs6232/rs6234/rs6235 PCSK1 single-nucleotide polymorphism clusters on proprotein convertase 1/3 biosynthesis and activity. Mol Genet Metab. 2011;104:682-687.
-
(2011)
Mol Genet Metab.
, vol.104
, pp. 682-687
-
-
Mbikay, M.1
Sirois, F.2
Nkongolo, K.K.3
Basak, A.4
Chretien, M.5
-
40
-
-
0028799007
-
Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide
-
Rouille Y, Martin S, Steiner DF. Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide. J Biol Chem. 1995;270:26488-26496.
-
(1995)
J Biol Chem.
, vol.270
, pp. 26488-26496
-
-
Rouille, Y.1
Martin, S.2
Steiner, D.F.3
-
41
-
-
0027460523
-
Purification and characterization of the prohormone convertase PC1(PC3)
-
Zhou Y, Lindberg I. Purification and characterization of the prohormone convertase PC1(PC3). J Biol Chem. 1993;268:5615-5623.
-
(1993)
J Biol Chem.
, vol.268
, pp. 5615-5623
-
-
Zhou, Y.1
Lindberg, I.2
-
42
-
-
0026665952
-
Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1
-
Benjannet S, Reudelhuber T, Mercure C, Rondeau N, Chretien M, Seidah NG. Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1. J Biol Chem. 1992;267:11417-11423.
-
(1992)
J Biol Chem.
, vol.267
, pp. 11417-11423
-
-
Benjannet, S.1
Reudelhuber, T.2
Mercure, C.3
Rondeau, N.4
Chretien, M.5
Seidah, N.G.6
-
43
-
-
80052831946
-
Hysteretic behavior of proprotein convertase 1/3 (PC1/3)
-
Icimoto MY, Barros NM, Ferreira JC, et al. Hysteretic behavior of proprotein convertase 1/3 (PC1/3). PLoS One. 2011;6:e24545.
-
(2011)
PLoS One.
, vol.6
, pp. e24545
-
-
Icimoto, M.Y.1
Barros, N.M.2
Ferreira, J.C.3
-
44
-
-
77956036259
-
Modulation of prohormone convertase 1/3 properties using site-directed mutagenesis
-
Ozawa A, Peinado JR, Lindberg I. Modulation of prohormone convertase 1/3 properties using site-directed mutagenesis. Endocrinology. 2010;151:4437-4445.
-
(2010)
Endocrinology.
, vol.151
, pp. 4437-4445
-
-
Ozawa, A.1
Peinado, J.R.2
Lindberg, I.3
-
45
-
-
0019978195
-
The internal pH and membrane potential of the insulin-secretory granule
-
Hutton JC. The internal pH and membrane potential of the insulin-secretory granule. Biochem J. 1982;204:171-178.
-
(1982)
Biochem J.
, vol.204
, pp. 171-178
-
-
Hutton, J.C.1
-
46
-
-
0022273429
-
Matrix free Ca2+ in isolated chromaffin vesicles
-
Bulenda D, Gratzl M. Matrix free Ca2+ in isolated chromaffin vesicles. Biochemistry. 1985;24:7760-7765.
-
(1985)
Biochemistry.
, vol.24
, pp. 7760-7765
-
-
Bulenda, D.1
Gratzl, M.2
-
47
-
-
0034651077
-
Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing
-
Fricker LD, McKinzie AA, Sun J, et al. Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J Neurosci. 2000;20: 639-648.
-
(2000)
J Neurosci.
, vol.20
, pp. 639-648
-
-
Fricker, L.D.1
McKinzie, A.A.2
Sun, J.3
-
48
-
-
0034640505
-
The SAAS granin exhibits structural and functional homology to 7B2 and contains a highly potent hexapeptide inhibitor of PC1
-
Cameron A, Fortenberry Y, Lindberg I. The SAAS granin exhibits structural and functional homology to 7B2 and contains a highly potent hexapeptide inhibitor of PC1. FEBS Lett. 2000;473:135-138.
-
(2000)
FEBS Lett.
, vol.473
, pp. 135-138
-
-
Cameron, A.1
Fortenberry, Y.2
Lindberg, I.3
-
49
-
-
4444279559
-
Prohormone convertase 1 (PC1) processing and sorting: Effect of PC1 propeptide and proSAAS
-
Lee SN, Prodhomme E, Lindberg I. Prohormone convertase 1 (PC1) processing and sorting: effect of PC1 propeptide and proSAAS. J Endocrinol. 2004;182:353-364.
-
(2004)
J Endocrinol.
, vol.182
, pp. 353-364
-
-
Lee, S.N.1
Prodhomme, E.2
Lindberg, I.3
-
50
-
-
0029147725
-
Structural elements that direct specific processing of different mammalian subtilisin-like prohormone convertases
-
Zhou A, Paquet L, Mains RE. Structural elements that direct specific processing of different mammalian subtilisin-like prohormone convertases. J Biol Chem. 1995;270:21509-21516.
-
(1995)
J Biol Chem.
, vol.270
, pp. 21509-21516
-
-
Zhou, A.1
Paquet, L.2
Mains, R.E.3
-
51
-
-
14244255720
-
Modulation of secretory granule-targeting efficiency by cis and trans compounding of sorting signals
-
Lacombe MJ, Mercure C, Dikeakos JD, Reudelhuber TL. Modulation of secretory granule-targeting efficiency by cis and trans compounding of sorting signals. J Biol Chem. 2005;280:4803-4807.
-
(2005)
J Biol Chem.
, vol.280
, pp. 4803-4807
-
-
Lacombe, M.J.1
Mercure, C.2
Dikeakos, J.D.3
Reudelhuber, T.L.4
-
52
-
-
33847765866
-
A hydrophobic patch in a charged a-helix is sufficient to target proteins to dense core secretory granules
-
Dikeakos JD, Lacombe MJ, Mercure C, Mireuta M, Reudelhuber TL. A hydrophobic patch in a charged a-helix is sufficient to target proteins to dense core secretory granules. J Biol Chem. 2007;282: 1136-1143.
-
(2007)
J Biol Chem.
, vol.282
, pp. 1136-1143
-
-
Dikeakos, J.D.1
Lacombe, M.J.2
Mercure, C.3
Mireuta, M.4
Reudelhuber, T.L.5
-
53
-
-
66149088834
-
Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease
-
Dikeakos JD, Di Lello P, Lacombe MJ, et al. Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease. Proc Natl Acad Sci USA. 2009;106: 7408-7413.
-
(2009)
Proc Natl Acad Sci USA.
, vol.106
, pp. 7408-7413
-
-
Dikeakos, J.D.1
Di Lello, P.2
Lacombe, M.J.3
-
54
-
-
34347380731
-
The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro
-
Rabah N, Gauthier D, Dikeakos JD, Reudelhuber TL, Lazure C. The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro. FEBS J. 2007; 274:3482-3491.
-
(2007)
FEBS J.
, vol.274
, pp. 3482-3491
-
-
Rabah, N.1
Gauthier, D.2
Dikeakos, J.D.3
Reudelhuber, T.L.4
Lazure, C.5
-
55
-
-
0027488373
-
The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing
-
Zhou A, Bloomquist BT, Mains RE. The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing. J Biol Chem. 1993;268:1763-1769.
-
(1993)
J Biol Chem.
, vol.268
, pp. 1763-1769
-
-
Zhou, A.1
Bloomquist, B.T.2
Mains, R.E.3
-
56
-
-
33744954869
-
Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulino-tropic polypeptide precursor
-
Ugleholdt R, Poulsen ML, Holst PJ, et al. Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulino-tropic polypeptide precursor. J Biol Chem. 2006;281:11050-11057.
-
(2006)
J Biol Chem.
, vol.281
, pp. 11050-11057
-
-
Ugleholdt, R.1
Poulsen, M.L.2
Holst, P.J.3
-
57
-
-
0032863468
-
Obesity in the mouse model of pro-opimelanocortin deficiency responds to peripheral melanocortin
-
Yaswen L, Diehl N, Brennan M, Hochgeschwender U. Obesity in the mouse model of pro-opimelanocortin deficiency responds to peripheral melanocortin. Nat Med. 1999;5:1066-1070.
-
(1999)
Nat Med.
, vol.5
, pp. 1066-1070
-
-
Yaswen, L.1
Diehl, N.2
Brennan, M.3
Hochgeschwender, U.4
-
58
-
-
0033112423
-
Immunohis-tochemical expressions of prohormone convertase (PC)1/3 and PC2 in carcinoids of various organs
-
Kajiwara H, Itoh Y, Itoh J, Yasuda M, Osamura RY. Immunohis-tochemical expressions of prohormone convertase (PC)1/3 and PC2 in carcinoids of various organs. Tokai J Exp Clin Med. 1999;24: 13-20.
-
(1999)
Tokai J Exp Clin Med.
, vol.24
, pp. 13-20
-
-
Kajiwara, H.1
Itoh, Y.2
Itoh, J.3
Yasuda, M.4
Osamura, R.Y.5
-
59
-
-
0030909584
-
Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 inhuman lung tumours
-
Mbikay M, Sirois F, Yao J, Seidah NG, Chretien M. Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 inhuman lung tumours. Br J Cancer. 1997;75:1509-1514.
-
(1997)
Br J Cancer.
, vol.75
, pp. 1509-1514
-
-
Mbikay, M.1
Sirois, F.2
Yao, J.3
Seidah, N.G.4
Chretien, M.5
-
60
-
-
0032420313
-
Key peptide processing enzymes are expressed by a variant form of small-cell carcinoma of the lung
-
North WG, Du J. Key peptide processing enzymes are expressed by a variant form of small-cell carcinoma of the lung. Peptides. 1998; 19:1743-1747.
-
(1998)
Peptides.
, vol.19
, pp. 1743-1747
-
-
North, W.G.1
Du, J.2
-
61
-
-
84876535078
-
Ectopic Cushing's syndrome secondary to pulmonary carcinoid tumor
-
Hashemzadeh S, Asvadi Kermani A, Ali-Asgharzadeh A, Halimi M, Soleimani M, Ladan A. Ectopic Cushing's syndrome secondary to pulmonary carcinoid tumor. Ann Thorac Surg. 2013;95:1797-1799.
-
(2013)
Ann Thorac Surg.
, vol.95
, pp. 1797-1799
-
-
Hashemzadeh, S.1
Asvadi Kermani, A.2
Ali-Asgharzadeh, A.3
Halimi, M.4
Soleimani, M.5
Ladan, A.6
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