Pack size and paracetamol overdose: 16 years later

Clinical Toxicology

Volumn 52, Issue 8, 2014, Pages 821-823

  Bateman, D Nicholas ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Analgesics; Drug regulation; Pack size; Paracetamol; Pharmaceuticals

Indexed keywords

DEXTROPROPOXYPHENE PLUS PARACETAMOL; NON PRESCRIPTION DRUG; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PARAQUAT; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; ANALGESIC AGENT;

HAZARD; HUMAN; INTOXICATION; MORTALITY; PUBLIC HEALTH; PUBLIC HEALTH PROBLEM; REGULATORY MECHANISM; REVIEW; DRUG PACKAGING; DRUG REGULATION; FEMALE; LEGAL ASPECT; MALE; NOTE; PACK SIZE; PHARMACEUTICALS;

ANALGESICS; DRUG REGULATION; PACK SIZE; PARACETAMOL; PHARMACEUTICALS;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; DRUG PACKAGING; FEMALE; HUMANS; MALE; POISONING;

EID: 84907058864     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2014.952432     Document Type: Review

References (14)

1. Bateman DN. Limiting paracetamol pack size: has it worked in the UK? Clin Toxicol 2009; 47:536-541.
2. FDA. Summary Minutes of the Joint Meeting of the Drug Safety and Risk Management Advisory Committee, Nonprescription Drugs Advisory Committee, and the Anesthetic and Life Support Drugs Advisory Committee June 29 and 30, 2009. 2009. http://www.fda.gov/ad-visorycommittees/calendar/ucm143083.htm (accessed 7 July 2014).
3. Hawton K, Bergen H, Simkin S, Dodd S, Pocock P, Bernal W, et al. Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses. BMJ 2013; 346:f403.
4. Leake I. Liver: Size matters: effects of reduced paracetamol pack sizes in England and Wales. Nat Rev Gastroenterol Hepatol 2013; 10:197.
5. Buckley N, Gunnell D. Does restricting pack size of paracetamol (acetaminophen) reduce suicides? PLoS Med. 2007; 4:e152.
6. Handley SA, Flanagan RJ. Drugs and other chemicals involved in fatal poisoning in England and Wales during 2000-2011. Clin Toxicol 2014; 52:1-12.
7. Morgan OW, Griffths C, Majeed A. Interrupted time-series analysis of regulations to reduce paracetamol (Acetaminophen) poisoning. PLoS Med 2007; 4:e105.
8. PHE. National Poisons Information Service-Annual Report 2012/2013. 2013. http://www.hpa.org.uk/Publications/ChemicalsPoisons National-PoisonsInformationServiceAnnualReports/(accessed 07/07 2014).
9. Pakravan N, Simpson KJ, Waring WS, Bates CM, Bateman DN. Renal injury at first presentation as a predictor for poor outcome in severe paracetamol poisoning referred to a liver transplant unit. Eur J Clin Pharmacol 2009; 65:163-168.
10. Bateman DN, Carroll R, Pettie J, Yamamoto T, Elamin ME, Peart L, et al. Effect of the UK's revised paracetamol poisoning management guidelines on admissions, adverse reactions, and costs of treatment. B J Clin Pharm 2014; doi:10.1111/bcp.12362.
11. Rumack BH, Bateman DN. Acetaminophen and acetylcysteine dose and duration: past, present and future. Clin Toxicol 2012; 50:91-8.
12. Hawton K, Bergen H, Simkin S, Arensman E, Corcoran P, Cooper J, et al. Impact of different pack sizes of paracetamol in the United Kingdom and Ireland on intentional overdoses: a comparative study. BMC Public Health 2011; 11:460.
13. Shah AD, Wood DM, Dargan PI. Internet survey of home storage of paracetamol by individuals in the UK. QJM 2013; 106:253-259.
14. Greene SL, Dargan PI, Lemam P, Jones AL. Paracetamol availability and recent changes in paracetamol poisoning: is the 1998 legislation limiting availability of paracetamol being followed? Postgrad Med J 2006; 82:520-523.