Failure of high-dose daptomycin for bacteremia caused by daptomycin-susceptible enterococcus faecium harboring liasr substitutions

Clinical Infectious Diseases

Volumn 59, Issue 9, 2014, Pages 1277-1280

  Munita, Jose M ^a,f   Mishra, Nagendra N ^d,e   Alvarez, Danya ^d   Tran, Truc T ^a   Diaz, Lorena ^g   Panesso, Diana ^a,g   Reyes, Jinnethe ^g   Murray, Barbara E ^a,b   Adachi, Javier A ^c   Bayer, Arnold S ^d,e   Arias, Cesar A ^a,b,g  

^a Division of Infectious Diseases   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^f UNIVERSIDAD DEL DESARROLLO   (Chile)

^g UNIVERSIDAD EL BOSQUE   (Colombia)

Author keywords

Daptomycin; Enterococcus faecium; resistance; treatment failure

Indexed keywords

AMPICILLIN; CYTARABINE; DALFOPRISTIN PLUS QUINUPRISTIN; DAPTOMYCIN; FLUDARABINE; GENTAMICIN; GRANULOCYTE COLONY STIMULATING FACTOR; IDARUBICIN; LINEZOLID; TIGECYCLINE; ANTIINFECTIVE AGENT;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BACTERICIDAL ACTIVITY; BLOOD CULTURE; BLOODSTREAM INFECTION; CASE REPORT; CATHETER INFECTION; CATHETER REMOVAL; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG TREATMENT FAILURE; ENTEROCOCCUS FAECIUM; FEBRILE NEUTROPENIA; GENETIC ASSOCIATION; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; LEUKEMIA RELAPSE; MALE; MINIMUM INHIBITORY CONCENTRATION; MONOTHERAPY; PULMONARY CANDIDIASIS; STREPTOCOCCUS INFECTION; YOUNG ADULT; DRUG EFFECTS; FATALITY; GRAM-POSITIVE BACTERIAL INFECTIONS; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; TREATMENT FAILURE;

ADULT; ANTI-BACTERIAL AGENTS; BACTEREMIA; CHEMOTHERAPY-INDUCED FEBRILE NEUTROPENIA; DAPTOMYCIN; ENTEROCOCCUS FAECIUM; FATAL OUTCOME; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TREATMENT FAILURE; YOUNG ADULT;

EID: 84907049035     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciu642     Document Type: Article

References (13)

1. Munita JM, Panesso D, Diaz L, et al. Correlation between mutations in liaFSR of Enterococcus faecium and MIC of daptomycin: revisiting daptomycin breakpoints. Antimicrob Agents Chemother 2012; 56:4354-9.
2. Arias CA, Panesso D, McGrath DM, et al. Genetic basis for in vivo daptomycin resistance in enterococci. N Engl J Med 2011; 365:892-900.
3. Tran TT, Panesso D, Gao H, et al. Whole-genome analysis of a daptomycin-susceptible Enterococcus faecium strain and its daptomycinresistant variant arising during therapy. Antimicrob Agents Chemother 2013; 57:261-8.
4. Miller C, Kong J, Tran TT, Arias CA, Saxer G, Shamoo Y. Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance. Antimicrob Agents Chemother 2013; 57:5373-83.
5. Diaz L, Tran TT, Munita JM, et al. Whole genome analyses of Enterococcus faecium with diverse daptomycin minimal inhibitory concentrations. Antimicrob Agents Chemother 2014; 58:4527-34.
6. Munita JM, Tran TT, Diaz L, et al. A liaF codon deletion abolishes daptomycin bactericidal activity against vancomycin-resistant Enterococcus faecalis. Antimicrob Agents Chemother 2013; 57:2831-3.
7. Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33:2233-9.
8. Tran TT, Panesso D, Mishra NN, et al. Daptomycin-resistant Enterococcus faecalis diverts the antibiotic molecule from the division septum and remodels cell membrane phospholipids. MBio 2013; 4:e00281-13.
9. Mishra NN, Bayer AS, Tran TT, et al. Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content. PLoS One 2012; 7:e43958.
10. Sakoulas G, Rose W, Nonejuie P, et al. Ceftaroline restores daptomycin activity against daptomycin-nonsusceptible vancomycin-resistant Enterococcus faecium. Antimicrob Agents Chemother 2014; 58: 1494-500.
11. Polidori M, Nuccorini A, Tascini C, et al. Vancomycin resistant Enterococcus faecium (VRE) bacteremia in infective endocarditis successfully treated with combination daptomycin and tigecycline. J Chemother 2011; 23:240-1.
12. Jaspan HB, Brothers AW, Campbell AJ, et al. Multidrug resistant Enterococcus faecium meningitis in a toddler: characterization of the organism and successful treatment with intraventricular daptomycin and intravenous tigecycline. Pediatr Infect Dis J 2010; 29:379-81.
13. Schutt AC, Bohm NM. Multidrug-resistant Enterococcus faecium endocarditis treated with combination tigecycline and high-dose daptomycin. Ann Pharmacother 2009; 43:2108-12.