A molecular basis for nicotine as a gateway drug

New England Journal of Medicine

Volumn 371, Issue 10, 2014, Pages 932-943

  Kandel, Eric R ^a,b,c   Kandel, Denise B ^c,d,e  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Kavli Institute for Brain Science   (United States)

^c Columbia University ^*  (United States)

^d College of Physicians ^*  (United States)

^e NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; HISTONE DEACETYLASE; HISTONE H3; HISTONE H4; NICOTINE; TRANSCRIPTION FACTOR FOSB;

ADDICTION; AMYGDALOID NUCLEUS; ARTICLE; BIOLOGICAL ACTIVITY; CORPUS STRIATUM; DEACETYLATION; DRUG USE; ENZYME ACTIVITY; ENZYME INHIBITION; GATEWAY HYPOTHESIS; GENE EXPRESSION; HIPPOCAMPUS; HISTONE ACETYLATION; HUMAN; HYPOTHESIS; LONG TERM MEMORY; LONG TERM POTENTIATION; MOLECULAR BIOLOGY; NERVE CELL PLASTICITY; NONHUMAN; NUCLEUS ACCUMBENS; SHORT TERM MEMORY; ANIMAL; BRAIN; DRUG EFFECT; LEARNING; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; BRAIN; COCAINE; HUMANS; LEARNING; MEMORY, LONG-TERM; MICE; NICOTINE; SUBSTANCE-RELATED DISORDERS;

EID: 84907006877     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMsa1405092     Document Type: Article

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