Effects of low-carbohydrate and low-fat diets: A randomized trial

Annals of Internal Medicine

Volumn 161, Issue 5, 2014, Pages 309-318

  Bazzano, Lydia A ^a   Hu, Tian ^a   Reynolds, Kristi ^b   Yao, Lu ^a   Bunol, Calynn ^a   Liu, Yanxi ^a   Chen, Chung Shiuan ^a   Klag, Michael J ^c   Whelton, Paul K ^a   He, Jiang ^a  

^a TULANE UNIVERSITY   (United States)

^b KAISER PERMANENTE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CREATININE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; INSULIN;

ADULT; AGED; APPETITE; ARTICLE; BODY COMPOSITION; BODY WEIGHT; CALORIC INTAKE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONSTIPATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETES MELLITUS; DIARRHEA; DIETARY INTAKE; FAT MASS; FATIGUE; FEMALE; FLATULENCE; FOLLOW UP; FOOD COMPOSITION; FRAMINGHAM RISK SCORE; HEADACHE; HEARTBURN; HUMAN; LIPOPROTEIN BLOOD LEVEL; LOSS OF APPETITE; LOW CARBOHYDRATE DIET; LOW FAT DIET; MAJOR CLINICAL STUDY; MALE; METABOLIC EQUIVALENT; NAUSEA; NUTRITIONAL COUNSELING; PARALLEL DESIGN; PHYSICAL ACTIVITY; POLYDIPSIA; POLYURIA; RANDOMIZED CONTROLLED TRIAL; RISK REDUCTION; THIRST; TRIACYLGLYCEROL BLOOD LEVEL; VOMITING; WAIST CIRCUMFERENCE; WEIGHT CHANGE; WEIGHT REDUCTION; BLOOD; BLOOD PRESSURE; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; DIET THERAPY; GLUCOSE BLOOD LEVEL; METABOLISM; MIDDLE AGED; OBESITY; RISK FACTOR; YOUNG ADULT;

ADULT; AGED; BLOOD GLUCOSE; BLOOD PRESSURE; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CREATININE; DIET, CARBOHYDRATE-RESTRICTED; DIET, FAT-RESTRICTED; FEMALE; HUMANS; INSULIN; MALE; MIDDLE AGED; OBESITY; RISK FACTORS; TRIGLYCERIDES; WAIST CIRCUMFERENCE; WEIGHT LOSS; YOUNG ADULT;

EID: 84906973574     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/M14-0180     Document Type: Article

References (31)

1. Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, et al American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics - 2013 update: a report from the American Heart Association. Circulation. 2013;127:e6-e245. [PMID: 23239837] doi:10.1161/CIR.0b013e31828124ad
2. Halton TL, Willett WC, Liu S, Manson JE, Albert CM, Rexrode K, et al. Low-carbohydrate-diet score and the risk of coronary heart disease in women. N Engl J Med. 2006;355:1991-2002. [PMID: 17093250]
3. Lagiou P, Sandin S, Lof M, Trichopoulos D, Adami HO, Weiderpass E. Low carbohydrate-high protein diet and incidence of cardiovascular diseases in Swedish women: prospective cohort study. BMJ. 2012;344:e4026. [PMID: 22735105] doi:10.1136/bmj.e4026
4. Stern L, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, et al. The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. Ann Intern Med. 2004;140:778-85. [PMID: 15148064]
5. Davis NJ, Tomuta N, Schechter C, Isasi CR, Segal-Isaacson CJ, Stein D, et al. Comparative study of the effects of a 1-year dietary intervention of a low-carbohydrate diet versus a low-fat diet on weight and glycemic control in type 2 diabetes. Diabetes Care. 2009;32:1147-52. [PMID: 19366978] doi:10.2337/dc08-2108
6. Sacks FM, Bray GA, Carey VJ, Smith SR, Ryan DH, Anton SD, et al. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. N Engl J Med. 2009;360:859-73. [PMID: 19246357] doi:10.1056/NEJMoa0804748
7. Krauss RM, Eckel RH, Howard B, Appel LJ, Daniels SR, Deckelbaum RJ, et al. AHA Dietary Guidelines: revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation. 2000;102:2284-99. [PMID: 11056107]
8. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002;106:3143-421. [PMID: 12485966]
9. Stone NJ, Van Horn L. Therapeutic lifestyle change and Adult Treatment Panel III: evidence then and now. Curr Atheroscler Rep. 2002;4:433-43. [PMID: 12361490]
10. Nutrition Data System for Research. The Minnesota Nutrition Data System. Minneapolis, MN: Univ of Minnesota; 2005.
11. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, et al Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension. 2005;45:142-61. [PMID: 15611362]
12. Allain CC, Poon LS, Chan CS, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem. 1974;20:470-5. [PMID: 4818200]
13. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502. [PMID: 4337382]
14. Samaha FF, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, et al. A low-carbohydrate as compared with a low-fat diet in severe obesity. N Engl J Med. 2003;348:2074-81. [PMID: 12761364]
15. Brehm BJ, Seeley RJ, Daniels SR, D'Alessio DA. A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. J Clin Endocrinol Metab. 2003;88:1617-23. [PMID: 12679447]
16. Seshadri P, Iqbal N, Stern L, Williams M, Chicano KL, Daily DA, et al. A randomized study comparing the effects of a low-carbohydrate diet and a conventional diet on lipoprotein subfractions and C-reactive protein levels in patients with severe obesity. Am J Med. 2004;117:398-405. [PMID: 15380496]
17. Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97:1837-47. [PMID: 9603539]
18. Molenberghs G, Kenward M. Missing Data in Clinical Studies. Hoboken, NJ: J Wiley; 2007.
19. Brinkworth GD, Noakes M, Buckley JD, Keogh JB, Clifton PM. Long-term effects of a very-low-carbohydrate weight loss diet compared with an isocaloric low-fat diet after 12 mo. Am J Clin Nutr. 2009;90:23-32. [PMID: 19439458] doi:10.3945/ajcn.2008.27326
20. Dansinger ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial. JAMA. 2005;293:43-53. [PMID: 15632335]
21. Foster GD, Wyatt HR, Hill JO, Makris AP, Rosenbaum DL, Brill C, et al. Weight and metabolic outcomes after 2 years on a low-carbohydrate versus low-fat diet: a randomized trial. Ann Intern Med. 2010;153:147-57. [PMID: 20679559] doi:10.7326/0003-4819-153-3-201008030-00005
22. Foster GD, Wyatt HR, Hill JO, McGuckin BG, Brill C, Mohammed BS, et al. A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med. 2003;348:2082-90. [PMID: 12761365]
23. Shai I, Schwarzfuchs D, Henkin Y, Shahar DR, Witkow S, Greenberg I, et al Dietary Intervention Randomized Controlled Trial (DIRECT) Group. Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. N Engl J Med. 2008;359:229-41. [PMID: 18635428] doi:10.1056/NEJMoa0708681
24. Gardner CD, Kiazand A, Alhassan S, Kim S, Stafford RS, Balise RR, et al. Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA. 2007;297:969-77. [PMID: 17341711]
25. Hu T, Mills KT, Yao L, Demanelis K, Eloustaz M, Yancy WS Jr, et al. Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol. 2012;176 Suppl 7:S44-54. [PMID: 23035144] doi:10.1093/aje/kws264
26. Ebbeling CB, Swain JF, Feldman HA, Wong WW, Hachey DL, Garcia-Lago E, et al. Effects of dietary composition on energy expenditure during weight-loss maintenance. JAMA. 2012;307:2627-34. [PMID: 22735432] doi:10.1001/jama.2012.6607
27. Gardner CD, Fortmann SP, Krauss RM. Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women. JAMA. 1996;276:875-81. [PMID: 8782636]
28. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med. 1999;340:115-26. [PMID: 9887164]
29. Cardillo S, Seshadri P, Iqbal N. The effects of a low-carbohydrate versus low-fat diet on adipocytokines in severely obese adults: three-year follow-up of a randomized trial. Eur Rev Med Pharmacol Sci. 2006;10:99-106. [PMID: 16875041]
30. U.S. Preventive Services Task Force. Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2009;150:396-404. [PMID: 19293072]
31. Larosa JC, Fry AG, Muesing R, Rosing DR. Effects of high-protein, low-carbohydrate dieting on plasma lipoproteins and body weight. J Am Diet Assoc. 1980;77:264-70. [PMID: 7410754]