MALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Powers, Thomas W ^a   Neely, Benjamin A ^a   Shao, Yuan ^a   Tang, Huiyuan ^d   Troyer, Dean A ^b   Mehta, Anand S ^c   Haab, Brian B ^d   Drake, Richard R ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d VAN ANDEL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN; GLYCOPEPTIDASE; N LINKED GLYCAN; TUMOR MARKER; UNCLASSIFIED DRUG; FORMALDEHYDE; PARAFFIN; POLYSACCHARIDE;

ADULT; AGED; ANIMAL TISSUE; ANTIGEN RETRIEVAL; ARTICLE; BRAIN CORTEX; CANCER DIAGNOSIS; CARBOHYDRATE ANALYSIS; CLINICAL ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; DIAGNOSTIC IMAGING; FEMALE; FORMALIN FIXED PARAFFIN EMBEDDED TISSUE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KIDNEY; LIVER CELL CARCINOMA; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION IMAGING MASS SPECTROMETRY; MEDULLA OBLONGATA; METHYLATION; MIDDLE AGED; MOUSE; NONHUMAN; OFF TISSUE PERMETHYLATION ANALYSIS; ON TISSUE COLLISION INDUCED FRAGMENTATION; PANCREAS CANCER; PROSTATE CANCER; STRUCTURE ANALYSIS; TISSUE MICROARRAY; TISSUE PRESERVATION; TISSUE SECTION; TISSUE SPECIFICITY; ANATOMY AND HISTOLOGY; ANIMAL; CHEMISTRY; HYDROLYSIS; LIVER TUMOR; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; MOLECULAR GENETICS; PANCREAS TUMOR; PATHOLOGY; PROSTATE TUMOR; TISSUE FIXATION;

ADULT; ANIMALS; CARBOHYDRATE SEQUENCE; CARCINOMA, HEPATOCELLULAR; FEMALE; FORMALDEHYDE; HUMANS; HYDROLYSIS; KIDNEY; LIVER NEOPLASMS; MALE; MICE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PANCREATIC NEOPLASMS; PARAFFIN; PARAFFIN EMBEDDING; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; POLYSACCHARIDES; PROSTATIC NEOPLASMS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TISSUE ARRAY ANALYSIS; TISSUE FIXATION;

EID: 84906965809     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106255     Document Type: Article

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