Effects of tissue-tolerable plasma on psoriasis vulgaris treatment compared to conventional local treatment: A pilot study

Clinical Plasma Medicine

Volumn 2, Issue 1, 2014, Pages 22-27

  Klebes, M ^a   Lademann, J ^a   Philipp, S ^a   Ulrich, C ^a   Patzelt, A ^a   Ulmer, M ^a   Kluschke, F ^a   Kramer, A ^b   Weltmann, K D ^c   Sterry, W ^a   Lange Asschenfeldt, B ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c LEIBNIZ INSTITUTE FOR PLASMA SCIENCE AND TECHNOLOGY   (Germany)

Author keywords

Antiseptic efficacy; Psoriasis; Tissue tolerable plasma (TTP)

Indexed keywords

PHUMASOL; SALICYLIC ACID; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ACUPUNCTURE LIKE SENSATION; ADULT; ARTICLE; BACTERIAL COLONIZATION; BATH; BRINE BATH; CLINICAL ARTICLE; COLONY FORMING UNIT; DERMATOLOGICAL EQUIPMENT; FEMALE; HUMAN; MALE; MEDICAL DEVICE COMPLICATION; PILOT STUDY; PRIORITY JOURNAL; PSORIASIS VULGARIS; RADIATION EQUIPMENT; TISSUE TOLERABLE PLASMA; TREATMENT RESPONSE; ULTRAVIOLET IRRADIATION;

EID: 84906939090     PISSN: 22128166     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cpme.2013.11.002     Document Type: Article

References (40)

1. Heinlin J., Isbary G., Stolz W., Morfill G., Landthaler M., Shimizu T., et al. Plasma applications in medicine with a special focus on dermatology. J Eur Acad Dermatol Venereol 2011, 25:1-11.
2. Lademann OR H., Patzelt A., Alborova A., Humme D., Weltmann K.D., Hartmann B., et al. Application of a plasma-jet for skin antisepsis: analysis of the thermal action of the plasma by laser scanning microscopy. Laser Phys Lett 2010, 7:458-462.
3. Kramer AH N.O., Assadian O., Below H., Bender C., Benkai H., Bröker B., et al. Chances and perspectives of the plasma medicine by use of tissue tolerable plasma (ttp). GMS Krankenhhyg Interdiszip 2009, 4:1216.
4. Lademann J., Richter H., Alborova A., Humme D., Patzelt A., Kramer A., et al. Risk assessment of the application of a plasma jet in dermatology. J Biomed Opt 2009, 14:054025.
5. Lademann O., Kramer A., Richter H., Patzelt A., Meinke M.C., Czaika V., et al. Skin disinfection by plasma-tissue interaction: comparison of the effectivity of tissue-tolerable plasma and a standard antiseptic. Skin Pharmacol Physiol 2011, 24:284-288.
6. Isbary G., Morfill G., Schmidt H.U., Georgi M., Ramrath K., Heinlin J., et al. A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients. Br J Dermatol 2010, 163:78-82.
7. Isbary G., Morfill G., Zimmermann J., Shimizu T., Stolz W. Cold atmospheric plasma: a successful treatment of lesions in Hailey-Hailey disease. Arch Dermatol 2011, 147:388-390.
8. Heinlin J., Isbary G., Stolz W., Zeman F., Landthaler M., Morfill G., et al. A randomized two-sided placebo-controlled study on the efficacy and safety of atmospheric non-thermal argon plasma for pruritus. J Eur Acad Dermatol Venereol 2011.
9. Lademann JU C., Patzelt A., Richter H., Kluschke F., Klebes M., Lademann O., et al. Risk assessment of the application of tissue-tolerable plasma on human skin. Clin Plasma Med 2013, 1:5-10.
10. Hammann A., Huebner N.O., Bender C., Ekkernkamp A., Hartmann B., Hinz P., et al. Antiseptic efficacy and tolerance of tissue-tolerable plasma compared with two wound antiseptics on artificially bacterially contaminated eyes from commercially slaughtered pigs. Skin Pharmacol Physiol 2010, 23:328-332.
11. Lademann J., Richter H., Schanzer S., Patzelt A., Thiede G., Kramer A., et al. Comparison of the antiseptic efficacy of tissue-tolerable plasma and an octenidine hydrochloride-based wound antiseptic on human skin. Skin Pharmacol Physiol 2012, 25:100-106.
12. Haertel B., Hahnel M., Blackert S., Wende K., von Woedtke T., Lindequist U. Surface molecules on hacat keratinocytes after interaction with non-thermal atmospheric pressure plasma. Cell Biol Int 2012, 36:1217-1222.
13. Kalghatgi S., Kelly C.M., Cerchar E., Torabi B., Alekseev O., Fridman A., et al. Effects of non-thermal plasma on mammalian cells. PLoS One 2011, 6:e16270.
14. Hubner N.O., Matthes R., Koban I., Randler C., Muller G., Bender C., et al. Efficacy of chlorhexidine, polihexanide and tissue-tolerable plasma against pseudomonas aeruginosa biofilms grown on polystyrene and silicone materials. Skin Pharmacol Physiol 2010, 23(Suppl.):28-34.
15. Isbary G., Heinlin J., Shimizu T., Zimmermann J.L., Morfill G., Schmidt H.U., et al. Successful and safe use of 2min cold atmospheric argon plasma in chronic wounds: results of a randomized controlled trial. Br J Dermatol 2012, 167:404-410.
16. Daeschlein G., Scholz S., Ahmed R., von Woedtke T., Haase H., Niggemeier M., et al. Skin decontamination by low-temperature atmospheric pressure plasma jet and dielectric barrier discharge plasma. J Hosp Infect 2012, 81:177-183.
17. Arjunan K.P., Friedman G., Fridman A., Clyne A.M. Non-thermal dielectric barrier discharge plasma induces angiogenesis through reactive oxygen species. J R Soc Interface 2012, 9:147-157.
18. Kalghatgi S., Friedman G., Fridman A., Clyne A.M. Endothelial cell proliferation is enhanced by low dose non-thermal plasma through fibroblast growth factor-2 release. Ann Biomed Eng 2010, 38:748-757.
19. Fluhr J.W., Sassning S., Lademann O., Darvin M.E., Schanzer S., Kramer A., et al. In vivo skin treatment with tissue-tolerable plasma influences skin physiology and antioxidant profile in human stratum corneum. Exp Dermatol 2012, 21:130-134.
20. Schafer T. Epidemiology of psoriasis. Review and the German perspective. Dermatology 2006, 212:327-337.
21. Micali G., Lacarrubba F., Musumeci M.L., Massimino D., Nasca M.R. Cutaneous vascular patterns in psoriasis. Int J Dermatol 2010, 49:249-256.
22. Weltmann KB R., von Woedtke T., Ehlbeck J., Foest R., Stieber M., Kindel E. Antimicrobial treatment of heat sensitive products by miniaturized atmospheric pressure plasma jets (appjs). J Phys D Appl Phys 2008, 41:194008.
23. Mattei P.L., Corey K.C., Kimball A.B. Psoriasis area severity index (pasi) and the dermatology life quality index (dlqi): the correlation between disease severity and psychological burden in patients treated with biological therapies. J Eur Acad Dermatol Venereol 2013.
24. Bergboer J.G., Oostveen A.M., de Jager M.E., Zeeuwen P.L., Joosten I., Seyger M.M., et al. Koebner phenomenon in psoriasis is not associated with deletion of late cornified envelope genes lce3b and lce3c. J Invest Dermatol 2012, 132:475-476.
25. Drucker A.M., Baibergenova A., Rosen C.F., Shear N.H. Narrowband UVB as an effective substitute for psoralen plus UVA: Lessons from a psoralen shortage. Photodermatol Photoimmunol Photomed 2012, 28:267-268.
26. Nast A., Boehncke W.H., Mrowietz U., Ockenfels H.M., Philipp S., Reich K., et al. German s3-guidelines on the treatment of psoriasis vulgaris (short version). Arch Dermatol Res 2012, 304:87-113.
27. Feldmeyer L., Shojaati G., Spanaus K.S., Navarini A., Theler B., Donghi D., et al. Phototherapy with UVB narrowband, UVA/UVBnb, and UVA1 differentially impacts serum 25-hydroxyvitamin-d3. J Am Acad Dermatol 2013.
28. Zerbinati N., Portale S., Palmieri B., Rottigni V., Iannitti T. A preliminary study to assess the efficacy of a new UVA1 laser for treatment of psoriasis. Photomed Laser Surg 2012, 30:610-614.
29. Fung M.A., Barr K.L. Current knowledge in inflammatory dermatopathology. Dermatol Clin 2012, 30:667-684.
30. Bussiahn RL N., Gesche R., v Woedke T., Weltmann K.-D. Plasmaquellen für biomedizinische applikationen. Hyg Med 2013, 38:5.
31. Wu A.S., Kalghatgi S., Dobrynin D., Sensenig R., Cerchar E., Podolsky E., et al. Porcine intact and wounded skin responses to atmospheric nonthermal plasma. J Surg Res 2013, 179:e1-e12.
32. Lange-Asschenfeldt B., Marenbach D., Lang C., Patzelt A., Ulrich M., Maltusch A., et al. Distribution of bacteria in the epidermal layers and hair follicles of the human skin. Skin Pharmacol Physiol 2011, 24:305-311.
33. Zhao G., Usui M.L., Underwood R.A., Singh P.K., James G.A., Stewart P.S., et al. Time course study of delayed wound healing in a biofilm-challenged diabetic mouse model. Wound Repair Regen 2012, 20:342-352.
34. Baz K., Cimen M.Y., Kokturk A., Yazici A.C., Eskandari G., Ikizoglu G., et al. Oxidant / antioxidant status in patients with psoriasis. Yonsei Med J 2003, 44:987-990.
35. Trouba K.J., Hamadeh H.K., Amin R.P., Germolec D.R. Oxidative stress and its role in skin disease. Antioxid Redox Signal 2002, 4:665-673.
36. Lima X.T., Kimball A.B. Skin carotenoid levels in adult patients with psoriasis. J Eur Acad Dermatol Venereol 2011, 25:945-949.
37. Camarasa J.M., Ortonne J.P., Dubertret L. Calcitriol shows greater persistence of treatment effect than betamethasone dipropionate in topical psoriasis therapy. J Dermatol Treat 2003, 14:8-13.
38. Monastirli A., Georgiou S., Pasmatzi E., Sakkis T., Badavanis G., Drainas D., et al. Calcipotriol plus short-contact dithranol: a novel topical combination therapy for chronic plaque psoriasis. Skin Pharmacol Appl Skin Physiol 2002, 15:246-251.
39. Zonneveld I.M., Rubins A., Jablonska S., Dobozy A., Ruzicka T., Kind P., et al. Topical tacrolimus is not effective in chronic plaque psoriasis. A pilot study. Arch Dermatol 1998, 134:1101-1102.
40. Lademann O., Richter H., Meinke M.C., Patzelt A., Kramer A., Hinz P., et al. Drug delivery through the skin barrier enhanced by treatment with tissue-tolerable plasma. Exp Dermatol 2011, 20:488-490.