Proton beam irradiation for non-AMD CNV: 2-Year results of a randomised clinical trial

British Journal of Ophthalmology

Volumn 98, Issue 9, 2014, Pages 1212-1217

  Chen, Ling ^a,b,c   Kim, Ivana K ^a   Lane, Anne M ^a   Gauthier, Danny ^d   Munzenrider, John E ^e   Gragoudas, Evangelos S ^a   Miller, Joan W ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c FUDAN UNIVERSITY   (China)

^d NOTRE DAME HOSPITAL   (Canada)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN; VERTEPORFIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EYE FUNDUS; EYE PHOTOGRAPHY; FEMALE; FLUORESCENCE ANGIOGRAPHY; HOSPITAL; HUMAN; MALE; OPHTHALMOLOGY; OPTICAL COHERENCE TOMOGRAPHY; PHOTODYNAMIC THERAPY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTON THERAPY; RANDOMIZED CONTROLLED TRIAL; RETINA MACULA AGE RELATED DEGENERATION; SUBRETINAL NEOVASCULARIZATION; UNITED STATES; VASCULAR DISEASE; VISION TEST; VISUAL ACUITY; VISUAL IMPAIRMENT;

CHOROIDAL NEOVASCULARIZATION; CLINICAL TRIAL; MYOPIA; PROTON BEAM IRRADIATION;

ADOLESCENT; ADULT; AGED; CHOROIDAL NEOVASCULARIZATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PATIENT SELECTION; PROSPECTIVE STUDIES; PROTONS; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RETINAL DISEASES; TREATMENT OUTCOME; VISUAL ACUITY; YOUNG ADULT;

EID: 84906937739     PISSN: 00071161     EISSN: 14682079     Source Type: Journal    
DOI: 10.1136/bjophthalmol-2013-304761     Document Type: Article

References (30)

1. Bottoni F, Tilanus M. The natural history of juxtafoveal and subfoveal choroidal neovascularization in high myopia. Int Ophthalmol 2001;24:249-55. (Pubitemid 37168157)
2. Verteporfin in Photodynamic Therapy Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia with verteporfin. 1-year results of a randomized clinical trial - VIP report no. 1. Ophthalmology 2001;108:841-52.
3. Brown J Jr, Folk JC, Reddy CV, et al. Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syndrome. Ophthalmology 1996;103:1100-5. (Pubitemid 26249561)
4. Macular Photocoagulation Study Group. Argon laser photocoagulation for neovascular maculopathy. Five-year results from randomized clinical trials. Arch Ophthalmol 1991;109:1109-14.
5. Arias L, Pujol O, Rubio M, et al. Long-term results of photodynamic therapy for the treatment of choroidal neovascularization secondary to angioid streaks. Graefes Arch Clin Exp Ophthalmol 2006;244:753-7. (Pubitemid 43923200)
6. Parodi MB, Di Crecchio L, Lanzetta P, et al. Photodynamic therapy with verteporfin for subfoveal choroidal neovascularization associated with multifocal choroiditis. Am J Ophthalmol 2004;138:263-9. (Pubitemid 39037431)
7. Browning AC, Chung AK, Ghanchi F, et al. Verteporfin photodynamic therapy of choroidal neovascularization in angioid streaks: one-year results of a prospective case series. Ophthalmology 2005;112:1227-31. (Pubitemid 40916929)
8. Heimann H, Gelisken F, Wachtlin J, et al. Photodynamic therapy with verteporfin for choroidal neovascularization associated with angioid streaks. Graefes Arch Clin Exp Ophthalmol 2005;243:1115-23. (Pubitemid 43124162)
9. Jurklies B, Bornfeld N, Schilling H. Photodynamic therapy using verteporfin for choroidal neovascularization associated with angioid streaks - long-term effects. Ophthalmic Res 2006;38:209-17. (Pubitemid 44213981)
10. Wachtlin J, Heimann H, Behme T, et al. Long-term results after photodynamic therapy with verteporfin for choroidal neovascularizations secondary to inflammatory chorioretinal diseases. Graefes Arch Clin Exp Ophthalmol 2003;241:899-906. (Pubitemid 37527049)
11. Blinder KJ, Blumenkranz MS, Bressler NM, et al. Verteporfin therapy of subfoveal choroidal neovascularization in pathologic myopia: 2-year results of a randomized clinical trial - VIP report no. 3. Ophthalmology 2003;110:667-73. (Pubitemid 36520061)
12. Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006;355:1419-31. (Pubitemid 44511557)
13. Brown DM, Kaiser PK, Michels M, et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 2006;355:1432-44. (Pubitemid 44511558)
14. Zambarakji HJ, Lane AM, Ezra E, et al. Proton beam irradiation for neovascular age-related macular degeneration. Ophthalmology 2006;113:2012-19. (Pubitemid 44635705)
15. Ciulla TA, Danis RP, Klein SB, et al. Proton therapy for exudative age-related macular degeneration: a randomized, sham-controlled clinical trial. Am J Ophthalmol 2002;134:905-6. (Pubitemid 35425461)
16. Flaxel CJ, Friedrichsen EJ, Smith JO, et al. Proton beam irradiation of subfoveal choroidal neovascularisation in age-related macular degeneration. Eye 2000;14(Pt 2):155-64. (Pubitemid 30265161)
17. Avila MP, Farah ME, Santos A, et al. Twelve-month short-term safety and visual-acuity results from a multicentre prospective study of epiretinal strontium-90 brachytherapy with bevacizumab for the treatment of subfoveal choroidal neovascularisation secondary to age-related macular degeneration. Br J Ophthalmol 2009;93:305-9.
18. Kirwan JF, Constable PH, Murdoch IE, et al. Beta irradiation: new uses for an old treatment: a review. Eye 2003;17:207-15. (Pubitemid 36410740)
19. Finger PT, Gelman YP, Berson AM, et al. Palladium-103 plaque radiation therapy for macular degeneration: results of a 7 year study. Br J Ophthalmol 2003;87:1497-503. (Pubitemid 38010556)
20. Yonemoto LT, Slater JD, Friedrichsen EJ, et al. Phase I/II study of proton beam irradiation for the treatment of subfoveal choroidal neovascularization in age-related macular degeneration: treatment techniques and preliminary results. Int J Radiat Oncol Biol Phys 1996;36:867-71. (Pubitemid 27008602)
21. Adams JA, Paiva KL, Munzenrider JE, et al. Proton beam therapy for age-related macular degeneration: development of a standard plan. Med Dosim 1999;24:233-8.
22. Suit H, Goldberg S, Niemierko A, et al. Proton beams to replace photon beams in radical dose treatments. Acta Oncol 2003;42:800-8. (Pubitemid 38091179)
23. Suit HD. Protons to replace photons in external beam radiation therapy? Clin Oncol (R Coll Radiol) 2003;15:S29-31. (Pubitemid 36150162)
24. Gelisken O, Hendrikse F, Deutman AF. A long-term follow-up study of laser coagulation of neovascular membranes in angioid streaks. Am J Ophthalmol 1988;105:299-303. (Pubitemid 18078115)
25. Chan WM, Lai TY, Liu DT, et al. Intravitreal bevacizumab (Avastin) for myopic choroidal neovascularisation: 1-year results of a prospective pilot study. Br J Ophthalmol 2009;93:150-4.
26. Sakaguchi H, Ikuno Y, Gomi F, et al. Intravitreal injection of bevacizumab for choroidal neovascularisation associated with pathological myopia. Br J Ophthalmol 2007;91:161-5. (Pubitemid 46202863)
27. Laud K, Spaide RF, Freund KB, et al. Treatment of choroidal neovascularization in pathologic myopia with intravitreal bevacizumab. Retina 2006;26:960-3. (Pubitemid 44547453)
28. Mandal S, Venkatesh P, Sampangi R, et al. Intravitreal bevacizumab (Avastin) as primary treatment for myopic choroidal neovascularization. Eur J Ophthalmol 2007;17:620-6. (Pubitemid 47605773)
29. Gharbiya M, Allievi F, Mazzeo L, et al. Intravitreal bevacizumab treatment for choroidal neovascularization in pathologic myopia: 12-month results. Am J Ophthalmol 2009;147:84-93 e1.
30. Heier JS, Brown D, Ciulla T, et al. Ranibizumab for choroidal neovascularization secondary to causes other than age-related macular degeneration: a phase I clinical trial. Ophthalmology 2011;118:111-18.