Incorporating high-pressure electroosmotic pump and a nano-flow gradient generator into a miniaturized liquid chromatographic system for peptide analysis

Analytica Chimica Acta

Volumn 844, Issue , 2014, Pages 90-98

  Chen, Apeng ^a   Lynch, Kyle B ^a   Wang, Xiaochun ^a   Lu, Joann J ^a   Gu, Congying ^a,b   Liu, Shaorong ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

^b Veritas Laboratories LLC   (United States)

Author keywords

Electroosmotic pump; Gradient generator; Nanoflow

Indexed keywords

LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; ORGANIC SOLVENTS; PEPTIDES;

CAPILLARY COLUMNS; CHROMATOGRAPHIC SYSTEMS; ELECTROOSMOTIC PUMPS; ISOCRATIC ELUTION; NANOFLOWS; PEPTIDE SEPARATION; PROTEOMIC ANALYSIS; UV ABSORBANCE DETECTORS;

ELECTROMAGNETIC PUMPS;

CYTOCHROME C; MYOGLOBIN; ORGANIC SOLVENT; PEPTIDE;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ELECTROSPRAY MASS SPECTROMETRY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURRE ELECTROOSMOTIC PUMP; MASS SPECTROMETER; OSMOTIC PUMP; PEPTIDE ANALYSIS; PRESSURE MEASUREMENT; PRIORITY JOURNAL; REPRODUCIBILITY; SEPARATION TECHNIQUE; ULTRAVIOLET SPECTROSCOPY; DEVICES; LIQUID CHROMATOGRAPHY; OSMOSIS; PRESSURE;

CHROMATOGRAPHY, LIQUID; OSMOSIS; PEPTIDES; PRESSURE;

EID: 84906934786     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2014.06.042     Document Type: Article

References (23)

1. Horváth C.G., Preiss B.A., Lipsky S.R. Fast liquid chromatography. Investigation of operating parameters and the separation of nucleotides on pellicular ion exchangers. Anal. Chem. 1967, 39:1422.
2. Horváth C.G., Lipsky S.R. Rapid analysis of ribonucleosides and bases at the picomole level using pellicular cation exchange resin in narrow bore columns. Anal. Chem. 1969, 41:1227.
3. Vissers J.P.C., Claessens H.A., Cramers C.A. Microcolumn liquid chromatography: instrumentation, detection and applications. J. Chromatogr. 1997, 779:1.
4. Vissers J.P.C. Recent developments in microcolumn liquid chromatography. J. Chromatogr. 1999, 856:117.
5. Scott R.P.W. Microbore columns in liquid chromatography. J. Chromatogr. Sci. 1980, 18:49.
6. Cappiello A., Famiglini G., Fiorucci C., Mangani F., Palma P., Siviero A. Variable-gradient generator for micro- and nano-HPLC. Anal. Chem. 2003, 75:1173.
7. Aebersold R., Mann M. Mass spectrometry-based proteomics. Nature 2003, 422:198.
8. Mechref Y., Novotny M.V. Structural investigations of glycoconjugates at high sensitivity. Chem. Rev. 2002, 102:321.
9. He C., Lu J.J., Jia Z., Wang W., Wang X., Dasgupta P.K., Liu S. Flow batteries for microfluidic networks: configuring an electroosmotic pump for nonterminal positions. Anal. Chem. 2011, 83:2430.
10. He C., Zhu Z., Gu C., Lu J., Liu S. Stacking open-capillary electroosmotic pumps in series to boost the pumping pressure to drive high-performance liquid chromatographic separations. J. Chromatogr. A 2012, 1227:253.
11. Gu C., Jia Z., Zhu Z., He C., Wang W., Morgan A., Lu J.J., Liu S. Miniaturized electroosmotic pump capable of generating pressures of more than 1200 bar. Anal. Chem. 2012, 84:9609.
12. Byun C., Wang X., Pu Q., Liu S. Electroosmosis-based nanopipettor. Anal. Chem. 2007, 79:3862.
13. Hirata Y., Novotny M. Techniques of capillary liquid chromatography. J. Chromatogr. 1979, 186:521.
14. Van der Wal S., Yang F.J.J. Gradient elution system for capillary and micro HPLC. High Resolut. Chromatogr. Commun. 1983, 6:216.
15. Takeuchi T., Niwa T., Ishii D. Stepwise gradient elution using switching valves in micro high-performance liquid chromatography. J. Chromatogr. 1987, 405:117.
16. Deguchi K., Ito S., Yoshioka S., Ogata I., Takeda A. Nanoflow gradient generator for capillary high-performance liquid chromatography. Anal. Chem. 2004, 76:1524.
17. Brennen R.A., Yin H., Killeen K.P. Microfluidic gradient formation for nanoflow chip LC. Anal. Chem. 2007, 79:9302.
18. Ishii D., Asai K., Hibi K., Jonokuchi T., Nagaya M. A study of micro-high-performance liquid chromatography: I. Development of technique for miniaturization of high-performance liquid chromatography. J. Chromatogr. 1977, 144:157.
19. Ishii D., Hashimoto Y., Asai H., Watanabe K., Takeuchi T. Solvent gradient elution in micro HPLC. J. High Resolut. Chromatogr. 1985, 8:543.
20. Takeuchi T., Ishii D. Continuous gradient elution in micro high-performance liquid chromatography. J. Chromatogr. 1982, 253:41.
21. Yi J., Heinecke J., Tan H., Ford P.C., Richter-Addo G.B. The distal pocket histidine residue in horse heart myoglobin directs the O-binding mode of nitrite to the heme iron. J. Am. Chem. Soc. 2009, 131:18119.
22. Hendgen-Cotta U.B., Flogel U., Kelm M., Rassaf T. Unmasking the Janus face of myoglobin in health and disease. J. Exp. Biol. 2010, 213:2734.
23. Guillemette J.G., Matsushimahibiya Y., Atkinson T., Smith M. Expression in Escherichia coli of a synthetic gene coding for horse heart myoglobin. Protein Eng. 1991, 4:585.