Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation

Acta Pharmacologica Sinica

Volumn 35, Issue 9, 2014, Pages 1177-1187

  Baek, Seung Ye ^a   Lee, Jaeseon ^a   Lee, Dong Gun ^a   Park, Mi Kyung ^a   Lee, Jennifer ^a,b   Kwok, Seung Ki ^a,b   Cho, Mi La ^a   Park, Sung Hwan ^a,b  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD19 ANTIGEN; IMMUNOGLOBULIN G; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 21; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN BCL 6; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; URSOLIC ACID; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTHRITIS; ARTICLE; AUTOIMMUNE ARTHRITIS; AUTOIMMUNE DISEASE; B LYMPHOCYTE DIFFERENTIATION; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; DISEASE SEVERITY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE REPRESSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INCIDENCE; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; TH17 CELL; TREATMENT DURATION; ANIMAL; B LYMPHOCYTE; CELL DIFFERENTIATION; DBA MOUSE; EXPERIMENTAL ARTHRITIS; IMMUNOLOGY; MALE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOIMMUNE DISEASES; B-LYMPHOCYTES; CELL DIFFERENTIATION; MALE; MICE; MICE, INBRED DBA; TH17 CELLS; TRITERPENES;

EID: 84906892444     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2014.58     Document Type: Article

References (0)