Antimicrobial treatment of asymptomatic bacteriuria in noncatheterized adults: A systematic review

Pharmacotherapy

Volumn 34, Issue 9, 2014, Pages 941-960

  Dull, Ryan B ^a   Friedman, Stacey K ^a   Risoldi, Zara M ^a   Rice, Eric C ^b   Starlin, Richard C ^c   Destache, Christopher J ^a  

^a CREIGHTON UNIVERSITY   (United States)

^b Alegent Creighton Health   (United States)

^c Infect Dis and Epidemiol Assoc   (United States)

Author keywords

antiinfective agents; antimicrobial stewardship; asymptomatic bacteriuria; evidence based practice; urinary tract infections

Indexed keywords

ANTIINFECTIVE AGENT;

ADULT; BACTERIAL INFECTIONS; BACTERIURIA; EVIDENCE BASED MEDICINE; HUMAN; ORGANIZATION AND MANAGEMENT; PATIENT CARE; PHARMACIST; PRACTICE GUIDELINE; PROFESSIONAL STANDARD;

ADULT; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BACTERIURIA; EVIDENCE-BASED MEDICINE; HUMANS; PATIENT CARE TEAM; PHARMACISTS; PRACTICE GUIDELINES AS TOPIC; PROFESSIONAL ROLE;

EID: 84906887054     PISSN: 02770008     EISSN: 18759114     Source Type: Journal    
DOI: 10.1002/phar.1437     Document Type: Review

References (56)

1. Lin E, Bhusal Y, Horwitz D, Shelburne SA, Trautner BW,. Overtreatment of enterococcal bacteriuria. Arch Intern Med 2012; 172: 33-8.
2. Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM,. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005; 40: 643-54.
3. Siegel SR, Siegel B, Sokoloff BZ, Kanter MH,. Urinary infection in infants and preschool children. Five-year follow-up. Am J Dis Child 1980; 134: 369-72.
4. Akhter AJ, Andrews GR, Caird FJ, Fallon RJ,. Urinary tract infection in the elderly: a population study. Age Ageing 1972; 1: 48-54.
5. Freedman LR,. Natural history of urinary infection in adults. Kidney Int 1975; 8: S96-100.
6. Mims AD, Norman DC, Yamamura RH, Yoshikawa TT,. Clinically inapparent (asymptomatic) bacteriuria in ambulatory elderly men: epidemiological, clinical, and microbiological findings. J Am Geriatr Soc 1990; 38: 1209-14.
7. Nicolle LE,. Asymptomatic bacteriuria: when to screen and when to treat. Infect Dis Clin North Am 2003; 17: 367-94.
8. Stamm WS,. Catheter-associated urinary tract infections: epidemiology, pathogenesis, and prevention. Am J Med 1991; 91 (suppl B): S65-71.
9. Warren JW, Tenney JH, Hoopes JM, Muncie HL, Anthony WC,. A prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters. J Infect Dis 1982; 146: 719-23.
10. Zabarsky TF, Sethi AK, Donskey CJ,. Sustained reduction in inappropriate treatment of asymptomatic bacteriuria in a long-term care facility through an education intervention. Am J Infect Control 2008; 36: 476-80.
11. Loeb M, Brazil K, Lohfeld L, et al. Effect of a multifaceted intervention on number of antimicrobial prescriptions for suspected urinary tract infections in residents of nursing homes: cluster randomized controlled trial. BMJ 2005; 331: 669-73.
12. Linares LA, Thornton DJ, Strymish J, Baker E, Gupta K,. Electronic memorandum decreases unnecessary antimicrobial use for asymptomatic bacteriuria and culture-negative pyuria. Infect Control Hosp Epidemiol 2011; 32: 644-8.
13. Chowdhury F, Sarkar K, Branche A, et al. Preventing the inappropriate treatment of asymptomatic bacteriuria at a community teaching hospital. J Community Hosp Intern Med Perspect 2012; 2: 17814.
14. Kelley D, Aaronson P, Poon E, McCarter YS, Bato B, Jankowski CA,. Evaluation of an antimicrobial stewardship approach to minimize overuse of antibiotics in patients with asymptomatic bacteriuria. Infect Control Hosp Epidemiol 2014; 35: 193-5.
15. Pavese P, Saurel N, Labarere J, et al. Does an educational session with an infectious diseases physician reduce the use of inappropriate antibiotic therapy for inpatients with positive urine culture results? A controlled before and after study. Infect Control Hosp Epidemiol 2009; 30: 596-9.
16. Hooton TM, Bradley SF, Cardenas DD, et al. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 international clinical practice guidelines from the Infectious Diseases Society of America. Clin Infect Dis 2010; 50: 625-63.
17. U.S. National Library of Medicine. Publication characteristics (Publication types)-Scope notes. National Institutes of Health Web site. Available from http://www.nlm.nih.gov/mesh/pubtypes.html. Accessed September 9, 2013.
18. Nicolle LE, Bjornson J, Harding G, MacDonell JA,. Bacteriuria in elderly institutionalized men. N Engl J Med 1983; 309: 1420-5.
19. Nicolle LE, Mayhew WJ, Bryan L,. Prospective randomized comparison of therapy and no therapy for asymptomatic bacteriuria in institutionalized elderly women. Am J Med 1987; 83: 27-33.
20. Nicolle LE, Mayhew JW, Bryan L,. Outcome following antimicrobial therapy for asymptomatic bacteriuria in elderly women resident in an institution. Age Ageing 1998; 17: 187-92.
21. Potts L, Cross S, MacLennan WJ, Watt B,. A double-blind comparative study of norfloxacin versus placebo in hospitalized elderly patients with asymptomatic bacteriuria. Arch Gerontol Geriatr 1996; 23: 153-61.
22. Ouslander JG, Shapira M, Schnelle JF, et al. Does eradicating bacteriuria affect the severity of chronic urinary incontinence in nursing home residents? Ann Intern Med 1995; 122: 749-54.
23. Renneberg J, Paerregaard A,. Single-day treatment with trimethoprim for asymptomatic bacteriuria in the elderly patient. J Urol 1984; 132: 934-5.
24. Abrutyn E, Mossey J, Berlin JA, et al. Does asymptomatic bacteriuria predict mortality and does antimicrobial treatment reduce mortality in elderly ambulatory women? Ann Intern Med 1994; 120: 827-33.
25. Abrutyn E, Berlin J, Mossey J, Pitsakis P, Levison M, Kaye D,. Does treatment of asymptomatic bacteriuria in older ambulatory women reduce subsequent symptoms of urinary tract infection? J Am Geriatr Soc 1996; 44: 293-5.
26. Giamarellou H, Dontas AS, Zorbas P, et al. Asymptomatic bacteriuria in freely voiding elderly subjects: long-term continuous versus pulse treatment with ofloxacin. Clin Drug Invest 1998; 15: 187-95.
27. Giamarellou H, Dontas AS, Petrikkos G, Gnardellis C, Zorbas P, Philippou P,. Survival of elderly bacteriuric subjects following long-term quinolone therapy. J Chemother 2007; 19: 185-92.
28. Boscia JA, Kobasa WD, Knight RA, Abrutyn E, Levison M, Kaye D,. Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. JAMA 1987; 257: 1067-71.
29. Dontas AS, Giamarellou H, Staszewska-Pistoni M, Petrikkos G, Iakovou M, Tzias V,. Short vs long cotrimoxazole in eradicating bacteriuria in the elderly. J Chemother 1992; 4: 114-8.
30. Giamarellou H, Iakovou M, Pistoni M, Petrikkos G, Dontas A, Sfikakis P,. Kinetics and comparative efficacy of ofloxacin versus co-trimoxazole in the asymptomatic bacteriuria of elderly subjects. Chemotherapy 1991; 37 (suppl 1): 19-24.
31. Asscher AW, Sussman M, Waters WE, et al. The clinical significance of asymptomatic bacteriuria in the nonpregnant woman. J Infect Dis 1969; 120: 17-26.
32. Cai T, Mazzoli S, Mondaini N, et al. The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: to treat or not to treat? Clin Infect Dis 2012; 55: 771-7.
33. Harding GK, Zhanel GG, Nicolle LE, Cheang M,. Antimicrobial treatment in diabetic women with asymptomatic bacteriuria. N Engl J Med 2002; 347: 1576-83.
34. Dalal S, Nicolle L, Marrs CF, Zhang L, Harding F, Foxman B,. Long-term Escherichia coli asymptomatic bacteriuria among women with diabetes mellitus. Clin Infect Dis 2009; 49: 491-7.
35. Sourander LB, Kasanen A,. A 5-year follow-up of bacteriuria in the aged. Gerontol Clin 1972; 14: 274-81.
36. Dontas AS, Kasviki-Charvati P, Papnayiotou PC, Marketos SG,. Bacteriuria and survival in old age. N Engl J Med 1981; 304: 939-43.
37. Salvador E, Wagenlehner WF, Kohler CD, et al. Comparison of asymptomatic bacteriuria Escherichia coli isolates from healthy individuals versus those from hospital patients shows that long-term bladder colonization selects for attenuated virulence phenotypes. Infect Immun 2012; 80: 668-78.
38. Midthun S, Paur R, Bruce AW, Midthun P,. Urinary tract infections in the elderly: a survey of physicians and nurses. Geriatr Nurs 2005; 26 (4): 245-51.
39. Wolfe RM, Sharp L, Wang RM,. Family physicians' opinions and attitudes to three clinical practice guidelines. J Am Board Fam Pract 2004; 17: 150-7.
40. Wolff SH, Grol R, Hutchinson A, Eccles M, Grimshaw J,. Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines. BMJ 1999; 318: 527-30.
41. James PA, Cowan TM, Graham RP, Jameroni BA,. Family physicians' attitudes about and use of clinical practice guidelines. Fam Pract 1997; 45: 341-7.
42. Borkowski NM, Allen WR,. Does attribution theory explain physicians' nonacceptance of clinical practice guidelines? Hosp Top 2003; 81: 9-21.
43. Mueller KL, Harris JS, Low P, Koziol-McLain J, Peplowski B,. Acceptance and self-reported use of national occupational medicine practice guidelines. J Occup Environ Med 2000; 42: 362-9.
44. James PA, Cowan TM, Graham RP,. Patient-centered clinical decisions and their impact on physician adherence to clinical guidelines. J Fam Pract 1998; 46: 311-8.
45. Woodford HJ, George J,. Diagnosis and management of urinary tract infection in hospitalized older people. J Am Geriatr Soc 2009; 57: 107-14.
46. Walker S, McGeer A, Simor AE, Armstrong-Evans M, Loeb M,. Why are antibiotics prescribed for asymptomatic bacteriuria in institutionalized elderly people? A qualitative study of physicians' and nurses' perceptions. CMAJ 2000; 163: 273-7.
47. Boscia JA, Kobasa WD, Abrutyn E, Levison ME, Kalpan AM, Kaye D,. Lack of association between bacteriuria and symptoms in the elderly. Am J Med 1986; 81: 979-82.
48. Silver SA, Baille L, Simor AE,. Positive urine cultures: a major cause of inappropriate antimicrobial use in hospitals? Can J Infect Dis Med Microbiol 2009; 20: 107-11.
49. Drekonja DM, Zarmbinski B, Johnson JR,. Preoperative urine cultures at a Veterans Affairs Medical Center. JAMA Intern Med 2013; 173: 71-2.
50. Bekeris LG, Jones BA, Walsh MK, Wagar EA,. Urine culture contamination: a College of American Pathologists Q-Probes study of 127 laboratories. Arch Pathol Lab Med 2008; 132: 913-7.
51. Wachter RM, Flanders SA, Fee C, Pronovost PJ,. Public reporting of antibiotic timing in patients with pneumonia: lessons from a flawed performance measure. Ann Intern Med 2008; 149: 29.
52. Morgan DJ, Meddings J, Saint S, et al. Does nonpayment for hospital-acquired catheter-associated urinary tract infections lead to overtesting and increased antimicrobial prescribing? Clin Infect Dis 2012; 55: 923-9.
53. Society for Healthcare Epidemiology of America; Infectious Diseases Society of America; Pediatric Infectious Diseases Society. Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol 2012; 33: 322-7.
54. Gross PA, Patel B,. Reducing antibiotic overuse: a call for a national performance measure for not treating asymptomatic bacteriuria. Clin Infect Dis 2007; 45: 1335-7.
55. Paige NM, Vazirani SS, Graber CJ,. The top 10 infectious disease pitfalls that hospitalists can avoid. J Hosp Med 2010; 5: 42-5.
56. Dellit TH, Owens RC, McGowan JE, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007; 44: 159-77.